公开(公告)号：US06187732B1

公开(公告)日：2001-02-13

申请号：US09146770

申请日：1998-09-03

申请人： Timothy Fowler ,  Colin Mitchinson

发明人： Timothy Fowler ,  Colin Mitchinson

IPC分类号： C11D3386

CPC分类号： C12N9/2437 ,  C12Y302/01004

摘要： The present invention relates to variant EGIII cellulases which have improved stability and/or performance. The variant cellulases have replacements at sensitive residues to improve stability and/or performance.

摘要翻译： 本发明涉及具有改善的稳定性和/或性能的变体EGIII纤维素酶。 变体纤维素酶在敏感残基中具有替代物以改善稳定性和/或性能。

公开(公告)号：US5874276A

公开(公告)日：1999-02-23

申请号：US448873

申请日：1995-05-24

申请人： Timothy Fowler ,  Kathleen A. Clarkson ,  Michael Ward ,  Katherine D. Collier ,  Edmund Larenas

发明人： Timothy Fowler ,  Kathleen A. Clarkson ,  Michael Ward ,  Katherine D. Collier ,  Edmund Larenas

IPC分类号： C12N15/09 ,  A23K1/165 ,  C12N1/15 ,  C12N9/42 ,  C12N15/31 ,  C12N15/80 ,  C12R1/885

CPC分类号： C12Y302/01004 ,  A23K20/189 ,  C12N15/80 ,  C12N9/2437 ,  C12Y302/01021 ,  C12Y302/01091

摘要： The present invention relates to the cloning and high level expression of novel truncated cellulase proteins or derivatives thereof in the filamentous fungus Trichoderma longibrachiatum. Further aspects of the present invention relate to fungal transformants that express the novel truncated cellulases and derivatives, and expression vectors comprising the DNA gene fragments or variants thereof that code for the truncated cellulases derived from Trichoderma longibrachiatum using genetic engineering techniques.