-
21.发明申请公开(公告)号：US20080262229A1
公开(公告)日：2008-10-23
申请号：US11816656
申请日：2006-02-24
申请人： William Brown , Andrew Griffin , Andrea Penwell
发明人： William Brown , Andrew Griffin , Andrea Penwell
IPC分类号： C07D241/04 , A61K31/4965 , A61P25/24
CPC分类号： C07D295/135 , C07D213/38
摘要： Compounds of formula: wherein R1 and R2 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 其中R 1和R 2如本说明书中所定义的化合物及其盐，对映异构体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
22.发明授权4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders 失效4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途公开(公告)号：US07241764B2
公开(公告)日：2007-07-10
申请号：US10533764
申请日：2003-11-05
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： C07D241/04 , A61K31/495 , A61P25/04
CPC分类号： C07D333/20 , C07D213/38 , C07D215/12 , C07D233/54 , C07D277/28 , C07D295/155 , C07D307/52
摘要： Compounds of general formula:[Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain
摘要翻译： 化合物通式：[化学式应在此插入。 请参阅纸质文件]其中R 1，R 2，R 3和R 3 3如本说明书中所定义，以及其盐，对映异构体 并制备包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛
-
23.发明申请Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开二芳基亚甲基哌啶衍生物，其制备方法及用途公开(公告)号：US20070066652A1
公开(公告)日：2007-03-22
申请号：US10557067
申请日：2004-05-13
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/453 , A61K31/452 , A61K31/445 , C07D211/22 , C07D409/02 , C07D405/02
CPC分类号： C07D405/06 , C07D211/70 , C07D411/06
摘要： Compounds of general formula: Formula (I) wherein R1, R2, R3 and A are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 通式为其中R 1，R 2，R 3和A的式（I）的化合物如说明书中所定义 作为其盐，对映体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
24.发明申请Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开二芳基亚甲基哌啶衍生物，其制备方法及用途公开(公告)号：US20060079555A1
公开(公告)日：2006-04-13
申请号：US10550661
申请日：2004-04-01
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： C07D211/32 , A61K31/445
CPC分类号： C07D417/12 , C07D211/70
摘要： Compounds of general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, m and n are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 制备其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，m和n如本说明书中所定义的通式（I）的化合物及其盐，对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
25.发明申请Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开二芳基亚甲基哌啶衍生物，其制备方法及用途公开(公告)号：US20070066653A1
公开(公告)日：2007-03-22
申请号：US10557068
申请日：2004-05-13
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/445 , C07D211/26
CPC分类号： C07D211/70
摘要： Compounds of general formula: Formula (I) wherein R1, R2, R3 and R4 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 通式为其中R 1，R 2，R 3和R 4的通式（I）的化合物是 如本说明书中所定义，以及其盐，对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
26.发明申请公开(公告)号：US20070293502A1
公开(公告)日：2007-12-20
申请号：US10596851
申请日：2005-01-05
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： C07D295/155 , A61K31/495 , A61P25/04 , A61P25/22
CPC分类号： C07D295/155
摘要： Compounds of formula: wherein R1, R2 and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 其中R 1，R 2和R 3的化合物如说明书中所定义，以及其盐，对映体和药物 制备包括这些化合物的组合物。 它们可用于治疗，特别是治疗疼痛。
-
27.发明申请Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开二芳基亚甲基哌啶衍生物，其制备方法及用途公开(公告)号：US20070099957A1
公开(公告)日：2007-05-03
申请号：US10555980
申请日：2004-05-13
申请人： William Brown , Andrew Griffin , Shujuan Jin
发明人： William Brown , Andrew Griffin , Shujuan Jin
IPC分类号： A61K31/454 , A61K31/445 , C07D211/26 , C07D401/02
CPC分类号： C07D211/70 , C07D401/06 , C07D417/06
摘要： Compounds of formula: (I) wherein R1, R2, R3, R4 and R7 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 式（I）的化合物，其中R 1，R 2，R 3，R 4和R 4， 本说明书中定义的，以及其盐，对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
28.发明申请Diarylmethylidene piperidine derivatives and their use as delta opiod receptor agonists 审中-公开二芳基亚甲基哌啶衍生物及其作为δ阿片受体激动剂的用途公开(公告)号：US20070066655A1
公开(公告)日：2007-03-22
申请号：US10555981
申请日：2004-05-13
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/453 , A61K31/452 , C07D409/02 , C07D405/02
CPC分类号： C07D211/70 , C07D401/06 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula: (Formula (I)) wherein R1, R2, R3, R4 and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain and anxiety.
摘要翻译： 通式为（式（I））的化合物，其中R 1，R 2，R 3，R 4， >和R 5如本说明书中所定义，以及其盐，对映体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛和焦虑症。
-
29.发明申请Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof as opoid receptors ligands 审中-公开二芳基亚甲基哌啶衍生物，其制备方法及其用作opoid受体配体公开(公告)号：US20060287361A1
公开(公告)日：2006-12-21
申请号：US10557069
申请日：2004-05-13
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/452 , C07D405/02 , C07D211/26 , A61K31/445
CPC分类号： C07D405/06 , C07D211/70 , C07D411/06
摘要： Compounds of general formula: (I) wherein R1, R2, R3 and A are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatment of pain and anxiety.
摘要翻译： 通式（I）的化合物，其中R 1，R 2，R 3和A如说明书中所定义，以及 盐，其对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛和焦虑症。
-
30.发明申请4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders 失效4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途公开(公告)号：US20060142296A1
公开(公告)日：2006-06-29
申请号：US10533764
申请日：2003-11-05
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/495 , A61K31/496
CPC分类号： C07D333/20 , C07D213/38 , C07D215/12 , C07D233/54 , C07D277/28 , C07D295/155 , C07D307/52
摘要： Compounds of general formula:[Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 化合物通式：[化学式应在此插入。 请参阅纸质文件]其中R 1，R 2，R 3和R 3 3如本说明书中所定义，以及其盐，对映异构体 并制备包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
-
-
-
-
-
-
-
-
搜索结果
47 条记录 (耗时 0.045 秒)
