摘要:
A method of determining the presence or the absence of a glaucoma risk, including the steps of detecting in vitro an allele and/or a genotype of a single nucleotide polymorphism which is located on a 31st base of a base sequence, in a sample from a subject, wherein the base sequence is at least one base sequence selected from the group consisting of base sequences shown in SEQ ID NOs: 203 to 752 or a complementary sequence thereto (step A), and comparing the allele and/or the genotype detected in the step A with at least one of an allele and/or a genotype, containing a high-risk allele, in the base sequences shown in SEQ ID NOs: 203 to 752 (step B). According to the method of the present invention, the level of a progressive risk of glaucoma in a sample donor can be determined by analyzing an allele or a genotype of a single nucleotide polymorphism in the present invention in the sample, so that the sample donor can take a preventive measure of glaucoma, or can receive appropriate treatments, on the basis of this risk.
摘要翻译:一种确定青光眼风险的存在或不存在的方法,包括以下步骤:在位于碱基序列的第31位的单核苷酸多态性的体外检测等位基因和/或基因型, 其中所述碱基序列是选自SEQ ID NO:203至752所示的碱基序列或其互补序列的至少一种碱基序列(步骤A),并比较检测到的等位基因和/或基因型 在SEQ ID NO:203〜752(步骤B)所示的碱基序列中具有含有高风险等位基因的等位基因和/或基因型中的至少一种的步骤A。 根据本发明的方法,可以通过分析样品中本发明的单核苷酸多态性的等位基因或基因型来确定样品供体中青光眼进行性风险的水平,使得样品供体可以 采取预防措施的青光眼,或者可以根据这种风险接受适当的治疗。
摘要:
A process of manufacturing the spark plug that includes a step in which a receiving die having an insertion hole and a taper portion is used, wherein a thread portion of the spark plug is inserted into the insertion hole and a seat portion of the spark plug is brought into contact with the taper portion, and a pressing force is applied to a rear end portion of a metallic shell of the spark plug so as to bend a rear end opening portion of the metallic shell, and to thereby form a crimped portion, whereby an insulator and the metallic shell are fixed together.
摘要:
A motorcycle includes a body frame having at least a pair of right and left or front and rear frame members with a storage box that is open upward between the pairing frame members. A riding seat covers the opening end of the storage box from above. The storage box includes a box main body arranged between the pair of frame members with a box constituent member that is detachably mounted below the box main body so as to form an electronic component storage chamber in cooperation with the box main body that composes a part of the wall portion of the storage box. The box constituent member is overlapped with at least a part of the frame members of a pair of frame members viewed in a plane with the box constituent member mounted to the box main body. The box constituent member bulges from the box main body.
摘要:
The present invention aims to provide a technique allowing the pictographic characters or the face marks to be converted to, for example, the corresponding, but more expressive and more vivid facial image of high picture quality and thereby to achieve compact but smooth and amusing communication.An system for distribution of images via e-mail constructed so that, when a text accompanied with pictographic characters is transmitted from a user terminal 1 and received by a communication processor 11 of a server 10, a registering station 12 and a image/text processor 15 read out user-registered images corresponding to the ideographic characters from a user database 13, then combine these images with the text and send back such combination to the user terminal 1 via the communication processor 11. According to this system, it is also possible for the image processor 16 to utilize the image database 14 for the purpose of synthesis of a morphing processed image, as a user instruct it, and to distribute the text accompanied with such morphing processed image.
摘要:
There is provided a spark plug wherein an insulator and a metallic shell, when observed in a section made by a plane including an axis of a spark plug, have therebetween a gap of less than 0.45 mm at a more front end side than an engagement position of a packing and a first insulator stepped portion, and the gap is provided axially from a most front end side engagement position of the packing and a first insulator stepped portion as a starting point to a finishing point that is apart from the starting point by 1.2 mm or more toward the front end side while being apart from a front end surface of the metallic shell by 7.9 mm or more toward a rear end side.
摘要:
In a method of manufacturing a sliding member, a granular spraying material is sprayed on at least a part of a surface of a body portion made of a structural material in at least partially fusing condition and in the direction which is parallel to or diagonal to a sliding surface. Then, a sprayed layer is formed by depositing the spraying material in the direction which is perpendicular to the sliding surface. The sliding surface is a section of the deposited spraying material which is obtained by grinding or cutting the sprayed layer in depositional direction. A piston comprises a piston body having a broad groove which is broader than a ring groove, a sprayed layer comprising a lower sprayed layer which is formed by spraying the spraying material in the direction which is diagonal to an outer periphery of the broad groove and which contains higher ratio of spraying particles having low fusion temperature, and an upper sprayed layer which is formed by spraying the spraying material in the direction which is perpendicular to the outer periphery of the broad groove and which contains higher ratio of spraying particles having high fusion temperature, and a ring groove which is formed by grinding or cutting the upper sprayed layer in depositional direction. Therefore, excellent wear resistance and the like can be obtained.
摘要:
An amino acid-enriched feed, industrially produced mixed feed or premix thereof which is obtainable by mixing (a) a feed raw material containing predominantly at least one feed component selected from the group consisting of corn gluten meal powder, corn gluten feed powder and an intermediate product thereof, said intermediate product being one obtained in a corn wet milling step with (b) an amino acid fermentation broth containing 3 to 80% by weight of an amino acid or its treated solution and thereafter drying the resultant mixture or by conducting drying during mixing of the raw materials (a) and (b). It has improved powder characteristics in flowability and homogeneity of the mixing components as compared with the case that crystalline amino acid is used as feed additive.
摘要:
A feed additive comprising granules containing amino acids and other fermentation products and a caking preventive agent. The feed additive has excellent flowability, exhibits less caking following moisture absorption, and is convenient to use. and store.
摘要:
Disclosed is a Zn-based composite-plated metallic material, comprising a plating layer on a metal substrate. The plating layer consists essentially of (1) Zn or as Zn alloy electroplated onto a metallic substrate and (2) the cathodic precipitation reaction product of aluminum, calcium, magnesium, strontium, titanium, zirconium, molybdenum, and/or tungsten. The latter metal constitutes 0.002 to 10% by weight of the plating layer. The cathodic precipitation-reaction product may be hydroxide, hydroxide hydrate or a phosphate.