公开(公告)号：US20130021605A1

公开(公告)日：2013-01-24

申请号：US13188941

申请日：2011-07-22

Applicant: Wei Yi ,  Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Zhiyong Li

Inventor： Wei Yi ,  Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Zhiyong Li

IPC: G01J3/44 ,  B32B3/10 ,  B23P17/04 ,  B32B5/16 ,  B82Y40/00 ,  B82Y15/00 ,  B82Y20/00

CPC classification number: G01N21/658 ,  B82Y15/00 ,  B82Y20/00 ,  B82Y40/00 ,  Y10T29/49826 ,  Y10T428/24893

Abstract: An apparatus includes a substrate and a plurality of nano-fingers attached at respective first ends to the substrate and freely movable along their lengths, in which a first set of the plurality of nano-fingers comprises a first physical characteristic, wherein a second set of the plurality of nano-fingers comprises a second physical characteristic, and wherein the first physical characteristic differs from the second physical characteristic.

Abstract translation: 一种装置包括：衬底和多个纳米指，其各自的第一端附接到衬底并且可沿其长度自由移动，其中多个纳米指的第一组包括第一物理特性，其中第二组 所述多个纳米指包含第二物理特性，并且其中所述第一物理特性与所述第二物理特性不同。

公开(公告)号：US08279437B2

公开(公告)日：2012-10-02

申请号：US12836097

申请日：2010-07-14

Applicant: Min Hu ,  Alexandre M. Bratkovski ,  Huel Pei Kuo ,  Jingjing Li ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

Inventor： Min Hu ,  Alexandre M. Bratkovski ,  Huel Pei Kuo ,  Jingjing Li ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

IPC: G01J3/44

CPC classification number: G01J3/18 ,  G01J3/44 ,  G01N21/65 ,  G01N2021/651

Abstract: An apparatus for detecting at least one species using Raman light detection includes at least one laser source for illuminating a sample containing the at least one species. The apparatus also includes a modulating element for modulating a spatial relationship between the sample and the light beams to cause relative positions of the sample and the light beams to be oscillated, in which Raman light at differing intensity levels are configured to be emitted from the at least one species based upon the different wavelengths of the light beams illuminating the sample. The apparatus also includes a Raman light detector and a post-signal processing unit configured to detect the at least one species.

Abstract translation: 用于使用拉曼光检测来检测至少一种物质的装置包括用于照亮含有至少一种物质的样品的至少一个激光源。 该装置还包括用于调制样品与光束之间的空间关系的调制元件，以使得样品和光束的相对位置发生振荡，其中以不同强度水平的拉曼光被配置为从at 基于照射样品的光束的不同波长的至少一种物质。 该装置还包括拉曼光检测器和被配置为检测至少一种物种的后信号处理单元。

公开(公告)号：US08269963B2

公开(公告)日：2012-09-18

申请号：US12771779

申请日：2010-04-30

Applicant: Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Zhiyong Li ,  R Stanley Williams

Inventor： Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Zhiyong Li ,  R Stanley Williams

IPC: G01J3/44

CPC classification number: G01N21/658

Abstract: A tunable apparatus for performing Surface Enhanced Raman Spectroscopy (SERS) includes a deformable layer and a plurality of SERS-active nanoparticles disposed at one or more locations on the deformable layer, wherein the one or more locations are configured to be illuminated with light of a pump wavelength to cause Raman excitation light to interact with the nanoparticles and produce enhanced Raman scattered light from molecules located in close proximity to the nanoparticles. In addition, a morphology of the deformable layer is configured to be controllably varied to modify an intensity of the Raman scattered light produced from the molecules.

Abstract translation: 用于进行表面增强拉曼光谱（SERS）的可调谐装置包括可变形层和设置在可变形层上的一个或多个位置处的多个SERS活性纳米颗粒，其中所述一个或多个位置被配置为用 泵浦波长以使拉曼激发光与纳米颗粒相互作用，并从靠近纳米颗粒的分子产生增强的拉曼散射光。 此外，可变形层的形态被配置为可控地改变以改变由分子产生的拉曼散射光的强度。

公开(公告)号：US20110267610A1

公开(公告)日：2011-11-03

申请号：US12772063

申请日：2010-04-30

Applicant: Min HU ,  Wei Wu ,  Fung Suong Ou ,  Zhen Peng ,  Zhiyong Li ,  R. Stanley Williams

Inventor： Min HU ,  Wei Wu ,  Fung Suong Ou ,  Zhen Peng ,  Zhiyong Li ,  R. Stanley Williams

IPC: G01J3/44

CPC classification number: G01N21/658 ,  G01N21/7746

Abstract: A compact sensor system comprising: an analysis cell configured for photon-matter interaction, where photons are received from a light source; and an integrated-optical spectral analyzer configured for identifying a set of frequencies, the integrated-optical spectral analyzer comprising: a waveguide coupled with the analysis cell, the waveguide configured for propagating a set of frequencies through the waveguide; one or more ring resonators coupled with the waveguide, the one or more ring resonators comprising a predetermined bandwidth and configured for capturing the set of frequencies corresponding to frequencies within the predetermined bandwidth; and one or more frequency detectors coupled with the one or more tunable ring resonators, the one or more frequency detectors configured for generating electrical signals that identify each of the set of frequencies.

Abstract translation: 一种紧凑的传感器系统，包括：配置用于光子 - 物质相互作用的分析单元，其中从光源接收光子; 所述集成光谱分析仪包括：与所述分析单元耦合的波导，所述波导被配置为通过所述波导传播一组频率;以及波导，其被配置为用于识别一组频率。 一个或多个与所述波导耦合的环形谐振器，所述一个或多个环形谐振器包括预定带宽并被配置用于捕获与所述预定带宽内的频率相对应的频率集合; 以及与所述一个或多个可调环形谐振器耦合的一个或多个频率检测器，所述一个或多个频率检测器被配置用于产生标识所述一组频率中的每一个的电信号。

公开(公告)号：US20110188035A1

公开(公告)日：2011-08-04

申请号：US12697156

申请日：2010-01-29

Applicant: Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

Inventor： Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

IPC: G01J3/44

CPC classification number: G01J3/44

Abstract: A vibrating tip surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a nano-needle configured to vibrate. The apparatus includes the nano-needle with a substantially sharp tip at a free end opposite an end attached to a substrate. The tip is configured to adsorb an analyte. The apparatus further includes a vibration source configured to provide an alternating current (AC) electric field that induces a vibration of the free end and the tip of the nano-needle. Vibration of the nano-needle under the influence of the AC electric field facilitates detection of a Raman scattering signal from the analyte adsorbed on the nano-needle tip. The system further includes a synchronous detector configured to be gated cooperatively with the vibration of the nano-needle. The method includes inducing the vibration, illuminating the vibrating tip to produce a Raman signal, and detecting the Raman signal using the detector.

Abstract translation: 振动尖端表面增强拉曼光谱（SERS）装置，系统和方法采用配置为振动的纳米针。 该装置包括在与连接到基底的端相对的自由端处具有基本尖锐的尖端的纳米针。 尖端构造成吸附分析物。 该装置还包括一个被配置为提供交流（AC）电场的振动源，其引起自由端和纳米针的尖端的振动。 在AC电场的影响下，纳米针的振动有助于检测吸附在纳米针尖上的分析物的拉曼散射信号。 该系统还包括配置为与纳米针的振动协同地选通的同步检测器。 该方法包括引起振动，照亮振动尖端以产生拉曼信号，并使用检测器检测拉曼信号。

公开(公告)号：US09244015B2

公开(公告)日：2016-01-26

申请号：US13636784

申请日：2010-04-20

Applicant: Zhiyong Li ,  Min Hu ,  Fung Suong Ou ,  Wei Wu

Inventor： Zhiyong Li ,  Min Hu ,  Fung Suong Ou ,  Wei Wu

IPC: G01J3/44 ,  B05D5/06 ,  B44C1/22 ,  C23C16/48 ,  C25D5/02 ,  G02B5/08 ,  G01N21/65

CPC classification number: G01N21/658 ,  G01N21/648

Abstract: A self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence. The self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence includes a substrate 110, and a plurality 120 of flexible columnar structures. A flexible columnar structure 120-1 of the plurality 120 includes a flexible column 120-1A, and a metallic cap 120-1B coupled to the apex 120-1 C of the flexible column 120-1A. At least the flexible columnar structure 120-1 and a second flexible columnar structure 120-2 are configured to self-arrange into a close-packed configuration with at least one molecule 220-1 disposed between at least the metallic cap 120-1B and a second metallic cap 120-2B of respective flexible columnar structure 120-1 and second flexible columnar structure 120-2.

Abstract translation: 用于表面增强发光的自配置发光增强装置101。 用于表面增强发光的自配置发光增强装置101包括基板110和多个120个柔性柱状结构。 多个120的柔性柱状结构120-1包括柔性柱120-1A以及耦合到柔性柱120-1A的顶点120-1C的金属盖120-1B。 至少柔性柱状结构120-1和第二柔性柱状结构120-2构造成自配置成紧密堆积构造，其中至少一个分子220-1设置在至少金属盖120-1B和 各个柔性柱状结构120-1的第二金属盖120-2B和第二柔性柱状结构120-2。

公开(公告)号：US08665432B2

公开(公告)日：2014-03-04

申请号：US12915148

申请日：2010-10-29

Applicant: Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

Inventor： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

IPC: G01N21/65

CPC classification number: G01J3/44 ,  G01N21/658

Abstract: An apparatus for performing surface enhanced Raman spectroscopy (SERS) includes a substrate and a plurality of nano-pillars, each of the plurality of nano-pillars having a first end attached to the substrate, a second end located distally from the substrate, and a body portion extending between the first end and the second end, in which the plurality of nano-pillars are arranged in an array on the substrate, and in which each of the plurality of nano-pillars is formed of a polymer material that is functionalized to expand in the presence of a fluid to cause gaps between the plurality of nano-pillars to shrink when the fluid is supplied onto the nano-pillars.

Abstract translation: 用于进行表面增强拉曼光谱（SERS）的设备包括基底和多个纳米柱，多个纳米柱中的每一个具有连接到基底的第一端，位于远离基底的第二端，以及 主体部分在所述第一端和所述第二端之间延伸，其中所述多个纳米柱以阵列布置在所述基底上，并且所述多个纳米柱中的每一个由聚合物材料形成，所述聚合物材料被官能化为 在存在流体的情况下膨胀，以便当将流体供应到纳米支柱上时，使多个纳米柱之间的间隙收缩。

公开(公告)号：US08559003B2

公开(公告)日：2013-10-15

申请号：US13384456

申请日：2009-09-17

Applicant: Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexandre M. Bratkovski

Inventor： Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexandre M. Bratkovski

IPC: G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00 ,  B82Y30/00

Abstract: An electrically driven device for surface enhanced Raman spectroscopy includes a first electrode, a substrate positioned proximate to the first electrode, a plurality of cone shaped protrusions formed integrally with or on a substrate surface, a Raman signal-enhancing material coated on each protrusion, and a second electrode positioned relative to the first electrode at a predetermined distance. Each of the protrusions has a tip with a radius of curvature ranging from about 0.1 nm to about 100 nm. The second electrode is positioned relative to the first electrode such that the electrodes together produce an electric field when a voltage bias is applied therebetween. The electric field has a field distribution that creates a stronger field gradient at a region proximate to the tips than at other portions of the substrate.

Abstract translation: 用于表面增强拉曼光谱的电驱动装置包括第一电极，靠近第一电极定位的基板，与基底表面一体地形成的多个锥形突起，涂覆在每个突起上的拉曼信号增强材料，以及 相对于第一电极以预定距离定位的第二电极。 每个突起具有具有约0.1nm至约100nm范围的曲率半径的尖端。 第二电极相对于第一电极定位，使得当在其之间施加电压偏置时，电极一起产生电场。 电场具有场分布，其在靠近尖端的区域处产生比在衬底的其它部分更强的场梯度。

公开(公告)号：US20130194570A1

公开(公告)日：2013-08-01

申请号：US13363006

申请日：2012-01-31

Applicant: Wei WU ,  Michael Josef Stuke ,  Zhiyong Li ,  James Elmer Abbott, JR. ,  Min Hu ,  Ansoon Kim

Inventor： Wei WU ,  Michael Josef Stuke ,  Zhiyong Li ,  James Elmer Abbott, JR. ,  Min Hu ,  Ansoon Kim

IPC: G01J3/44 ,  G01J3/28

CPC classification number: G01J3/44 ,  G01J3/0205 ,  G01J3/26

Abstract: An apparatus for performing spectroscopy includes an optical waveguide comprising a fluidic channel to receive a fluid sample, in which the optical waveguide is to propagate lightwaves at a set of frequencies. The apparatus also includes a wavelength selective device coupled to the optical waveguide, in which the wavelength selective device comprises a predetermined bandwidth and is to capture frequencies of light within the predetermined bandwidth. The apparatus further includes a detector coupled to the wavelength selective device to generate signals that identify the frequencies captured by the wavelength selective device.

Abstract translation: 用于执行光谱学的装置包括光波导，其包括用于接收流体样品的流体通道，其中光波导将以一组频率传播光波。 该装置还包括耦合到光波导的波长选择装置，其中波长选择装置包括预定带宽并且捕获预定带宽内的光的频率。 该装置还包括耦合到波长选择装置的检测器，以产生识别由波长选择装置捕获的频率的信号。

公开(公告)号：US20130027698A1

公开(公告)日：2013-01-31

申请号：US13636784

申请日：2010-04-20

Applicant: Zhiyong Li ,  Min Hu ,  Fung Suong Ou ,  Wei Wu

Inventor： Zhiyong Li ,  Min Hu ,  Fung Suong Ou ,  Wei Wu

IPC: G01J3/44 ,  C25D5/02 ,  C23C16/48 ,  B44C1/22 ,  G02B5/08 ,  B05D5/06

CPC classification number: G01N21/658 ,  G01N21/648

Abstract: A self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence. The self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence includes a substrate 110, and a plurality 120 of flexible columnar structures. A flexible columnar structure 120-1 of the plurality 120 includes a flexible column 120-1A, and a metallic cap 120-1B coupled to the apex 120-1 C of the flexible column 120-1A. At least the flexible columnar structure 120-1 and a second flexible columnar structure 120-2 are configured to self-arrange into a close-packed configuration with at least one molecule 220-1 disposed between at least the metallic cap 120-1B and a second metallic cap 120-2B of respective flexible columnar structure 120-1 and second flexible columnar structure 120-2.

Abstract translation: 用于表面增强发光的自配置发光增强装置101。 用于表面增强发光的自配置发光增强装置101包括基板110和多个120个柔性柱状结构。 多个120的柔性柱状结构120-1包括柔性柱120-1A以及耦合到柔性柱120-1A的顶点120-1C的金属盖120-1B。 至少柔性柱状结构120-1和第二柔性柱状结构120-2构造成自配置成紧密堆积构造，其中至少一个分子220-1设置在至少金属盖120-1B和 各个柔性柱状结构120-1的第二金属盖120-2B和第二柔性柱状结构120-2。