公开(公告)号：US10410749B2

公开(公告)日：2019-09-10

申请号：US15098153

申请日：2016-04-13

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

IPC: G01N33/48 ,  G16H50/20 ,  G06F19/00 ,  C12Q1/6874 ,  G16B40/00 ,  G16B50/00 ,  G16H10/40 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10357157B2

公开(公告)日：2019-07-23

申请号：US15098110

申请日：2016-04-13

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

IPC: G01N33/48 ,  A61B5/00 ,  C12Q1/689 ,  G06F19/00 ,  G16B40/00 ,  G16B50/00 ,  G16H50/20 ,  G16H50/80 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10346592B2

公开(公告)日：2019-07-09

申请号：US15203589

申请日：2016-07-06

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

IPC: G01N33/48 ,  G06F19/00 ,  A61K35/741 ,  A61K35/742 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747 ,  A61K45/06 ,  G16H50/70 ,  G16H50/20 ,  G16H10/40 ,  G16B20/00 ,  G16B30/00 ,  G16B50/00 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10294532B2

公开(公告)日：2019-05-21

申请号：US15606709

申请日：2017-05-26

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

IPC: G01N33/48 ,  C12Q1/689 ,  C12Q1/6869 ,  G16B30/00 ,  C12Q1/6888 ,  G06G7/58

Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.

公开(公告)号：US10290375B2

公开(公告)日：2019-05-14

申请号：US15645076

申请日：2017-07-10

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

IPC: G01N33/48 ,  G16H50/20 ,  G06F19/00 ,  G16B35/00 ,  G16B40/00 ,  G16B50/00 ,  G16C20/60 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US20190136298A1

公开(公告)日：2019-05-09

申请号：US16084964

申请日：2016-09-09

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid ,  Siavosh Rezvan Behbahani

IPC: C12Q1/689 ,  C12Q1/6883 ,  G16B30/00 ,  G16H50/20 ,  G16H20/10

Abstract: Methods, compositions, and systems are provided for detecting one or more an eczema issues by characterizing the microbiome of an individual, monitoring such effects, and/or determining, displaying, or promoting a therapy for the eczema issue. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and/or functional diversity datasets. Methods, compositions, and systems are also provided for generating a characterization model and/or therapy model for eczema.

公开(公告)号：US10282520B2

公开(公告)日：2019-05-07

申请号：US15621378

申请日：2017-06-13

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G01N33/48 ,  G06F19/00 ,  G16B35/00 ,  G16B40/00 ,  G16B50/00 ,  G16C20/60 ,  G16H50/20 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10169541B2

公开(公告)日：2019-01-01

申请号：US15497072

申请日：2017-04-25

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Catalina Valdivia ,  Daniel Almonacid

IPC: G01N33/48 ,  G06F19/00 ,  G06F19/24 ,  G06F19/28 ,  C12Q1/6874 ,  G16H50/20 ,  G06G7/58

Abstract: Embodiments of a method and system for characterizing a skin-related condition in relation to a user can include one or more of: a handling network operable to collect containers comprising material from a set of users, the handling network comprising a sequencing system operable to determine microorganism sequences from sequencing the material; a microbiome characterization system operable to: determine at least one of microbiome composition data and microbiome functional diversity data based on the microorganism sequences, collect supplementary data associated with the skin-related condition for the set of users, and transform the supplementary data and the at least one of the microbiome composition data and the microbiome functional diversity data into a characterization model; and a therapy system operable to promote a treatment to the user for the skin-related condition based on characterizing the user with the characterization model in relation to the skin-related condition.

公开(公告)号：US20180286520A1

公开(公告)日：2018-10-04

申请号：US15997654

申请日：2018-06-04

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid ,  Inti Pedroso ,  Catalina Valdivia ,  Rodrigo Ortiz ,  Paz Tapia

IPC: G16H50/70 ,  G16H10/40 ,  G06F19/28

CPC classification number: G16H50/70 ,  G16B20/00 ,  G16B50/00 ,  G16H10/40 ,  G16H50/20 ,  Y02A90/26

Abstract: Embodiments of a method and/or system for characterizing one or more sleep-related conditions can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process associated with the one or more sleep-related conditions, based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a sleep-related characterization process for the one or more sleep-related conditions, and/or determining one or more therapies S140.

公开(公告)号：US20180122513A1

公开(公告)日：2018-05-03

申请号：US15849041

申请日：2017-12-20

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G06F19/28 ,  G06F19/24

CPC classification number: G16H50/20 ,  C12Q1/6874 ,  G06F19/3418 ,  G16B40/00 ,  G16B50/00 ,  G16H10/40 ,  G16H40/67 ,  Y02A90/26

Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.