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公开(公告)号:US20150211078A1
公开(公告)日:2015-07-30
申请号:US14593436
申请日:2015-01-09
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Jessica Richman
CPC classification number: C12Q1/689 , C12Q1/6869 , C12Q1/6888 , G06F19/22
Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.
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公开(公告)号:US10410749B2
公开(公告)日:2019-09-10
申请号:US15098153
申请日:2016-04-13
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号:US10357157B2
公开(公告)日:2019-07-23
申请号:US15098110
申请日:2016-04-13
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
IPC: G01N33/48 , A61B5/00 , C12Q1/689 , G06F19/00 , G16B40/00 , G16B50/00 , G16H50/20 , G16H50/80 , G06G7/58
Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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24.
公开(公告)号:US10346592B2
公开(公告)日:2019-07-09
申请号:US15203589
申请日:2016-07-06
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Daniel Almonacid , Jessica Richman , Siavosh Rezvan Behbahani
IPC: G01N33/48 , G06F19/00 , A61K35/741 , A61K35/742 , A61K35/744 , A61K35/745 , A61K35/747 , A61K45/06 , G16H50/70 , G16H50/20 , G16H10/40 , G16B20/00 , G16B30/00 , G16B50/00 , G06G7/58
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号:US10294532B2
公开(公告)日:2019-05-21
申请号:US15606709
申请日:2017-05-26
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Jessica Richman , Daniel Almonacid
IPC: G01N33/48 , C12Q1/689 , C12Q1/6869 , G16B30/00 , C12Q1/6888 , G06G7/58
Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.
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26.
公开(公告)号:US10290375B2
公开(公告)日:2019-05-14
申请号:US15645076
申请日:2017-07-10
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Jessica Richman , Daniel Almonacid
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号:US10287637B2
公开(公告)日:2019-05-14
申请号:US14593436
申请日:2015-01-09
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Jessica Richman
IPC: G01N33/48 , C12Q1/689 , C12Q1/6869 , G16B30/00 , C12Q1/6888 , G06G7/58
Abstract: A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.
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公开(公告)号:US20190136298A1
公开(公告)日:2019-05-09
申请号:US16084964
申请日:2016-09-09
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Jessica Richman , Daniel Almonacid , Siavosh Rezvan Behbahani
IPC: C12Q1/689 , C12Q1/6883 , G16B30/00 , G16H50/20 , G16H20/10
Abstract: Methods, compositions, and systems are provided for detecting one or more an eczema issues by characterizing the microbiome of an individual, monitoring such effects, and/or determining, displaying, or promoting a therapy for the eczema issue. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and/or functional diversity datasets. Methods, compositions, and systems are also provided for generating a characterization model and/or therapy model for eczema.
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29.
公开(公告)号:US10282520B2
公开(公告)日:2019-05-07
申请号:US15621378
申请日:2017-06-13
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号:US10169541B2
公开(公告)日:2019-01-01
申请号:US15497072
申请日:2017-04-25
Applicant: uBiome, Inc.
Inventor: Zachary Apte , Jessica Richman , Catalina Valdivia , Daniel Almonacid
Abstract: Embodiments of a method and system for characterizing a skin-related condition in relation to a user can include one or more of: a handling network operable to collect containers comprising material from a set of users, the handling network comprising a sequencing system operable to determine microorganism sequences from sequencing the material; a microbiome characterization system operable to: determine at least one of microbiome composition data and microbiome functional diversity data based on the microorganism sequences, collect supplementary data associated with the skin-related condition for the set of users, and transform the supplementary data and the at least one of the microbiome composition data and the microbiome functional diversity data into a characterization model; and a therapy system operable to promote a treatment to the user for the skin-related condition based on characterizing the user with the characterization model in relation to the skin-related condition.
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