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    Portable concentrator
    21.
    发明授权
    Portable concentrator 有权
    便携式集中器

    公开(公告)号：US08726744B2

    公开(公告)日：2014-05-20

    申请号：US13028897

    申请日：2011-02-16

    Applicant: David Scott Alburty ,  Andrew Edward Page ,  Alec D. Adolphson ,  Zachary A. Packingham

    Inventor： David Scott Alburty ,  Andrew Edward Page ,  Alec D. Adolphson ,  Zachary A. Packingham

    IPC: G01N1/22 ,  G01N1/00 ,  G01N1/04

    CPC classification number: G01N1/4055 ,  G01N2001/4088

    Abstract: The present disclosure provides devices, systems and methods for concentrating a fluid sample. A portable or hand-held concentrator is used to draw the fluid sample through a filter into an internal chamber, capturing target particles on the filter. An elution cartridge containing an elution fluid is used to recover the captured particles into a reduced fluid volume. The hand-held concentrator includes a tip, which, when opened, allows the hand-held concentrator to draw the fluid sample into the tip and through the filter wall into the internal chamber. The drawing occurs due to a vacuum or wicking source in the internal chamber of the hand-held concentrator. The target particles are captured on the filter. The elution fluid contains a foaming agent and is held under a head pressure of gas soluble in the elution fluid. The target particles are eluted from the filter into the reduced fluid volume using an elution foam that is formed when the elution fluid is released from the elution cartridge. Embodiments of the hand-held concentrator are entirely self-contained and can operate without electrical power.

    Abstract translation: 本公开提供用于浓缩流体样品的装置，系统和方法。 使用便携式或手持式浓缩器将流体样品通过过滤器吸入内部室中，捕获过滤器上的目标颗粒。 使用含有洗脱液的洗脱柱将捕获的颗粒还原成减少的流体体积。 手持式集中器包括一个尖端，当打开时，该端头允许手持式集中器将流体样品吸入顶端并通过过滤器壁进入内部室。 由于在手持式集中器的内部腔室中有真空或芯吸源，因此出现了这种情况。 目标颗粒被捕获在过滤器上。 洗脱液含有发泡剂，并保持在可溶于洗脱液的气体的头部压力下。 使用在洗脱液体从洗脱药筒释放洗脱液时形成的洗脱泡沫，将目标颗粒从过滤器洗脱成减少的流体体积。 手持式集中器的实施例是完全独立的并且可以在没有电力的情况下工作。

    Aerosol collector
    24.
    外观设计
    Aerosol collector 有权

    公开(公告)号：USD1014779S1

    公开(公告)日：2024-02-13

    申请号：US29794875

    申请日：2021-06-15

    Applicant: Boehringer Ingelheim Vetmedica GmbH ,  INNOVAPREP LLC

    Designer： Zachary A. Packingham ,  Steven D. Graham

    Abstract: FIG. 1 is a front perspective view of an aerosol collector showing our new design;
    FIG. 2 is a front elevational view thereof;
    FIG. 3 is a back elevational view thereof;
    FIG. 4 is a right side elevational view thereof;
    FIG. 5 is a left side elevational view thereof;
    FIG. 6 is a top plan view thereof;
    FIG. 7 is a bottom plan view thereof; and,
    FIG. 8 is a bottom perspective view thereof.
    The broken lines in the drawings depict portions of the aerosol collector that form no part of the claimed design.

    Liquid to liquid biological particle concentrator with disposable fluid path
    28.
    发明授权
    Liquid to liquid biological particle concentrator with disposable fluid path 有权
    液体与液体生物颗粒浓缩器与一次性流体路径

    公开(公告)号：US09593359B2

    公开(公告)日：2017-03-14

    申请号：US14084385

    申请日：2013-11-19

    Applicant: InnovaPrep LLC

    Inventor： Andrew Edward Page ,  Zachary A. Packingham ,  David Scott Alburty ,  Alec D. Adolphson

    IPC: C12Q1/24 ,  G01N1/40

    CPC classification number: G01N1/4077 ,  B01L3/0275 ,  B01L2200/026 ,  B01L2200/0631 ,  B01L2300/0681 ,  B01L2300/161 ,  C12Q1/24 ,  G01N2001/4088

    Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.

    Abstract translation: 公开了高效和快速的基于过滤的浓缩装置，系统和方法，其具有样品流体管线和封装在一次性尖端中的过滤器，其将从液体悬浮的稀释进料悬浮液中的生物颗粒进行浓缩。 保留样品浓缩物或滞留物悬浮液，同时在单独的流动流中除去分离的流体。 然后将浓缩物从一次性尖端中以一定体积的洗脱液分配。 悬浮的生物颗粒包括尺寸范围为约0.001微米至20微米直径的蛋白质/毒素，病毒，DNA和/或细菌等材料。 这些颗粒的浓度对于在稀释悬浮液中检测目标颗粒是有利的，因为将它们浓缩成小体积使得它们更易于检测。 将一次性尖端附接到仪器的所有导管组合成尖端上端的单个连接点。

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