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公开(公告)号：US20180071458A1
公开(公告)日：2018-03-15
申请号：US15560197
申请日：2016-03-30
申请人： Novo Nordisk A/S
发明人： Brian Oestergaard
CPC分类号： A61M5/24 , A61M5/2466 , A61M5/3155 , A61M5/31551 , A61M2005/2407 , A61M2005/2418 , A61M2005/2433 , A61M2005/2485 , A61M2207/00
摘要： A cartridge holder assembly is provided, comprising an enclosed cartridge, a distal portion and a proximal portion. The enclosed cartridge defines a longitudinal axis and comprises a generally cylindrical main portion, a distal outlet portion having a neck portion with a circumferential shoulder portion, and a proximal portion having an opening surrounded by a circumferential rim. The distal portion comprises a distal support structure engaging the cartridge neck portion and being adapted to support the cartridge against movement in the distal direction, and the proximal portion comprises a proximal support structure engaging the cartridge circumferential rim and being adapted to support the cartridge against movement in the proximal direction. The proximal support structure is essentially non-deformed, and the distal support structure engaging the cartridge neck portion is plastically deformed.
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公开(公告)号：US09897980B2
公开(公告)日：2018-02-20
申请号：US14232502
申请日：2012-07-12
CPC分类号： G05B11/00 , A61M5/24 , A61M5/31551 , A61M5/31556 , A61M5/3156 , A61M5/31568 , A61M5/31585 , A61M37/00 , A61M2005/3126 , A61M2205/3306 , A61M2205/50 , A61M2205/8212 , G06M1/22 , G06M1/272 , G07F17/0092
摘要： A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.
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公开(公告)号：US20180028757A1
公开(公告)日：2018-02-01
申请号：US15549097
申请日：2016-02-10
IPC分类号： A61M5/315
CPC分类号： A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/31575 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： The present invention relates to a drive mechanism for an injection device for setting and dispensing of a dose of a medicament, the drive mechanism comprising:—a tubular shaped housing component (12, 45) extending in an axial direction (z) and comprising an inner thread (46),—a tubular shaped display member (80) having an outer thread (81) engaged with the inner thread (46), and—a dose member (90) axially displaceable between a dose setting position (S) and a dose dispensing position relative to the display member (80),—wherein the display member (80) comprises at least one blocking member (87) on its outer circumference to axially engage with a blocking structure (18) on an inside facing sidewall portion (12a) of the housing component (12, 45) to block an axial displacement of the dose member (90) from the dose setting position (S) towards the dose dispensing position.
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公开(公告)号：US20180015228A1
公开(公告)日：2018-01-18
申请号：US15207871
申请日：2016-07-12
申请人： CAREBAY EUROPE LTD.
发明人： Slobodan Stefanov , Thad Miley
CPC分类号： A61M5/31595 , A61M5/20 , A61M5/24 , A61M5/31511 , A61M5/31513 , A61M5/31528 , A61M5/31536 , A61M5/31541 , A61M5/31551 , A61M5/31585 , A61M5/31593 , A61M2205/581 , A61M2205/582
摘要： A multi-dose medicament delivery device is presented having a housing, a medicament container assembly, a dose drum, a plunger rod, and an activation assembly. The dose drum is supported in the housing via a threaded connection, wherein the dose drum is axially movable with respect to the housing in a backward direction from an initial position to at least one dosing position when rotated in a first direction in order to set a dose to be delivered, and axially movable with respect to the housing in a forward direction from said dosing position to the initial position when rotated in a second, opposite direction in order to deliver the dose set. The plunger rod is operationally associated with the stopper and supported in the housing via a threaded connection, wherein the threaded connection is configured to axially guide the plunger rod toward the device front end when the plunger rod is rotated in the second direction.
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公开(公告)号：US09861757B2
公开(公告)日：2018-01-09
申请号：US15241566
申请日：2016-08-19
申请人： Novo Nordisk A/S
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/24 , A61M5/31535 , A61M5/3155 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement.Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension.The injection device is suitable for injecting insulin.
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公开(公告)号：US09861755B2
公开(公告)日：2018-01-09
申请号：US14435845
申请日：2013-10-14
申请人： Novo Nordisk A/S
CPC分类号： A61M5/31551 , A61M5/20 , A61M5/3146 , A61M5/315 , A61M5/31515 , A61M5/31553 , A61M5/31583 , A61M5/31593 , A61M2005/2013 , F04C2270/0421
摘要： The present invention relates to a torsion spring driven injection device for delivering multiple set doses of a liquid drug from a cartridge by moving a plunger forward inside the cartridge. The torsion spring (134) applies a rotational torque onto a drive member (120) engaging a piston rod (115) which is then driven forward by this rotation. The piston rod driver can be coupled and de-coupled from the torsion spring mechanism. In the de-coupled position, the piston rod driver is freely rotatable and can thus rotate if the piston rod is moved axially. A further torsion arrangement (124) is preferably provided such that a torque is build up between the piston rod driver and the housing whenever the piston rod is moved backwards. This torsion arrangement urges the piston rod driver to rotate in a direction bringing the piston rod forward into abutment with the plunger.
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公开(公告)号：US20180001031A1
公开(公告)日：2018-01-04
申请号：US15675428
申请日：2017-08-11
申请人： HASELMEIER AG
发明人： Joachim Keitel
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/31558 , A61M5/3156 , A61M5/3158 , A61M2005/2026 , A61M2205/581 , A61M2205/582
摘要： An injection device includes a housing; a receptacle for injection fluid; a dosing piston to press out the injection fluid; a feed part connected to the dosing piston via a first threaded connection; a slide having a thread of a second threaded connection; and, a setting part having a thread of a third threaded connection and configured to set an amount of injection fluid to be dispensed. The setting part moves in the distal direction by virtue of the third threaded connection when the amount of injection fluid to be dispensed is being set. The setting part can move in the proximal direction when the injection fluid is pressed out. A latching unit defines a latching position of the setting part and acts between the setting part and housing. Each latching position has an unequivocal rotational position of the setting part in relation to the housing assigned thereto.
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公开(公告)号：US09855391B2
公开(公告)日：2018-01-02
申请号：US13762623
申请日：2013-02-08
申请人： Novo Nordisk A/S
CPC分类号： A61M5/31545 , A61M5/24 , A61M5/31528 , A61M5/31535 , A61M5/31541 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31558 , A61M5/31585 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a housing having an interior thread formed as an outwardly pointing thread carried on an upstanding tower centrally located in the injection device. The outwardly pointing thread forms a first thread connection with an interior thread of a rotatable scale drum. The injection device further comprises a driver for moving a piston rod forward when moved axially. The driver operates the piston rod through a second thread connection having a pitch different than the first thread connection.
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公开(公告)号：US09849244B2
公开(公告)日：2017-12-26
申请号：US13320639
申请日：2010-05-28
申请人： David Plumptre , James Davies , Christopher Jones , Robert Veasey
发明人： David Plumptre , James Davies , Christopher Jones , Robert Veasey
CPC分类号： A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31543 , A61M5/31551 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492
摘要： A drug delivery device is provided comprising a dose setting mechanism having a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism.
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公开(公告)号：US20170340831A1
公开(公告)日：2017-11-30
申请号：US15673207
申请日：2017-08-09
申请人： SHL GROUP AB
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31561 , A61M5/3158 , A61M5/31595 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A dose setting mechanism for a medicament delivery device is presented having a locking assembly that reliably and consistently unlocks a dose injection button and concurrently a lead screw when the dose setting mechanism is transitioned from a non-activated state to an activated state. This locking assembly uses a rotating plate having a locking protrusion that engages a radial projecting tab on a rotationally fixed plunger rod nut. An alignment member is also presented that prevents rotational drift of a dosing member.
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