DEVICE WITH CO-EXTRUDED BODY AND FLEXIBLE INNER BLADDER AND RELATED APPARATUS AND METHOD
    331.
    发明申请
    DEVICE WITH CO-EXTRUDED BODY AND FLEXIBLE INNER BLADDER AND RELATED APPARATUS AND METHOD 有权
    具有共挤出体和柔性内刀片的装置及相关装置和方法

    公开(公告)号:US20100089946A1

    公开(公告)日:2010-04-15

    申请号:US12577126

    申请日:2009-10-09

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.

    Abstract translation: 一种装置包括包含第一聚合物的第一部分和与第一部分相比具有相对柔性的第二部分,并且包括基本上不能与第一聚合物结合的第二聚合物。 该装置的腔室相对于环境气氛可气密地密封,并且由(i)第二部分的内部和/或(ii)形成在第一和第二部分之间的空间限定。 该装置的第三部分包括可与第一和第二聚合物结合的第三聚合物,并将第一和第二部分彼此固定地固定。

    Container and valve assembly for storing and dispensing substances, and related method
    332.
    发明授权
    Container and valve assembly for storing and dispensing substances, and related method 有权
    用于储存和分配物质的容器和阀门组件及相关方法

    公开(公告)号:US07637401B2

    公开(公告)日:2009-12-29

    申请号:US10976349

    申请日:2004-10-28

    Abstract: A container including a nozzle and body depending therefrom. The body is preferably tubular and defines an interior which retains a product to be dispensed. A cap engages the nozzle to prevent inadvertent release of the product. In order to dispense the product, the cap is removed and pressure is applied to the body and the nozzle allows release of the product. The nozzle releases the product without exposing the remaining product to the external atmosphere, thus the sterility of the interior of the body is maintained and the shelf life of the product is increased. The nozzle includes an inner body, coupled to the tubular body, surrounded by a flexible outer cover. A seam between the inner body and flexible outer cover forms a one-way release valve wherein a portion of the seam remains closed during dispensing the product.

    Abstract translation: 一种容器,其包括从其排出的喷嘴和主体。 主体优选地是管状的并且限定保持要分配的产品的内部。 盖子与喷嘴接合以防止产品的意外释放。 为了分配产品,盖被去除并且压力施加到主体上,并且喷嘴允许释放产品。 喷嘴释放产品而不将剩余的产品暴露于外部大气,从而维持身体内部的不整洁性并且提高了产品的保质期。 该喷嘴包括一个连接到管状主体的内部主体,被一个柔性的外盖包围。 内体和柔性外盖之间的接缝形成单向释放阀,其中在分配产品期间,接缝的一部分保持关闭。

    Container and valve assembly for storing and dispensing substances, and related method
    333.
    发明授权
    Container and valve assembly for storing and dispensing substances, and related method 有权
    用于储存和分配物质的容器和阀门组件及相关方法

    公开(公告)号:US07637400B2

    公开(公告)日:2009-12-29

    申请号:US11301659

    申请日:2005-12-12

    CPC classification number: B65D35/46 B65D47/205 B65D47/2056 B65D47/2081

    Abstract: A container and valve assembly for storing and dispensing substances including edible substances. The container is a tubular body that defines a storage chamber for storing the substance and a head portion for supports the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seem between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.

    Abstract translation: 用于储存和分配包括可食用物质的物质的容器和阀组件。 容器是限定用于储存物质的储存室的管状体和用于支撑阀组件的头部。 阀组件包括阀体和由包括阀部分的柔性外盖包围的阀座。 在阀部分和阀座之间似乎形成单向释放阀,其中当物质被分配时,接缝的一部分保持关闭。 为了分配物质,将压力施加到身体,迫使物质进入阀组件,这进而控制物质的流动和释放,而不将剩余物质暴露于外部大气; 因此,保持储存室和剩余物质的不育性,并且物质的保存期限增加。

    Sterile filling machine having needle filling station and conveyor
    334.
    发明授权
    Sterile filling machine having needle filling station and conveyor 有权
    无菌灌装机具有针加料站和输送机

    公开(公告)号:US07556066B2

    公开(公告)日:2009-07-07

    申请号:US11527775

    申请日:2006-09-25

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a heat resealable stopper and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the stopper and chamber for sterilizing the container. The previously sterilized containers are then transported through another sterilizing chamber, such as an e-beam chamber, to sterilize the penetrable surface. A needle is moved into engagement with the stopper to pierce the sterilized penetrable surface of the stopper and inject the substance through the needle and into the chamber of the container. Laser energy is then transmitted onto the penetrated surface of the stopper to fuse the stopper material and hermetically re-seal the stopper.

    Abstract translation: 提供了一种无菌灌装机及相关方法,用于无菌填充具有物质的容器。 容器包括可热再封塞的塞子和用于在其中容纳物质的腔室。 密封的空容器经受能够穿过塞子和室的辐射,以对容器进行灭菌。 先前灭菌的容器然后通过另一个灭菌室,如电子束室输送,以对可穿透表面进行消毒。 针头与塞子移动接合以刺穿塞子的消毒的可渗透表面,并将物质通过针头注入容器的腔室。 然后将激光能量传递到塞子的穿透表面上,以使塞子材料熔化并密封地重新密封塞子。

    METHOD FOR FORMULATING AND ASEPTICALLY FILLING LIQUID PRODUCTS
    335.
    发明申请
    METHOD FOR FORMULATING AND ASEPTICALLY FILLING LIQUID PRODUCTS 审中-公开
    用于制备和自由填充液体产品的方法

    公开(公告)号:US20090098250A1

    公开(公告)日:2009-04-16

    申请号:US12245681

    申请日:2008-10-03

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: An apparatus and method are provided for formulating and aseptically filling liquid products. A first liquid source includes at least one first liquid component; a second liquid source includes at least one second liquid component; and a container includes a body defining an empty, sterile storage chamber therein that is sealed with respect to ambient atmosphere. The container is introduced into a sterile filling chamber. A first filling member coupled in fluid communication with the first liquid source is placed in fluid communication with the storage chamber of the container located in the sterile filling chamber, and the first liquid component is aseptically introduced through the first filling member and into the storage chamber. A second filling member coupled in fluid communication with the second liquid source is placed in fluid communication with the storage chamber of the container located in the sterile filling chamber, and the second liquid component is aseptically introduced through the second filling member and into the storage chamber and, in turn, the first and second liquid components are combined into a liquid product formulation within the sterile chamber of the container. The first and second filling members are withdrawn from fluid communication with the storage chamber of the container located within the sterile filling chamber, and the filled storage chamber is sealed with respect to ambient atmosphere to hermetically seal the liquid product formulation within the storage chamber of the container.

    Abstract translation: 提供了用于配制和无菌灌装液体产品的装置和方法。 第一液体源包括至少一个第一液体组分; 第二液体源包括至少一个第二液体组分; 并且容器包括在其中限定相对于环境大气密封的空的无菌储存室的主体。 将容器引入无菌填充室。 与第一液体源流体连通的第一填充构件被放置成与位于无菌填充室中的容器的储存室流体连通,第一液体组分被无菌地通过第一填充构件引入储存室 。 与第二液体源流体连通的第二填充构件被放置成与位于无菌填充室中的容器的储存室流体连通,并且第二液体组分被无菌地通过第二填充构件引入并进入储存室 而又将第一和第二液体组分组合成容器无菌室内的液体产品制剂。 第一和第二填充构件与位于无菌填充室内的容器的储存室流体连通地取出,并且填充的储存室相对于环境大气密封,以将液体产品配制物气密地密封在储存室内 容器。

    Device with needle penetrable and laser resealable portion and related method
    336.
    发明授权
    Device with needle penetrable and laser resealable portion and related method 有权
    带针穿透和激光可重复密封的部件及相关方法

    公开(公告)号:US07500498B2

    公开(公告)日:2009-03-10

    申请号:US11933300

    申请日:2007-10-31

    Applicant: Daniel Py

    Inventor: Daniel Py

    Abstract: A device and method are provided for needle penetrating and filling a chamber with a predetermined substance, and laser resealing a resulting needle hole in the device. A needle penetrable and laser resealable portion of the device is pierceable with a needle to form a needle aperture therethrough to fill the chamber through the needle, and is laser resealable to hermetically seal the needle aperture by applying laser radiation at a predetermined wavelength and power thereto. The needle penetrable and laser resealable portion defines a predetermined wall thickness in an axial direction thereof, and includes a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and laser resealable portion during penetration by and withdrawal of the needle. The thermoplastic includes a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at the predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.

    Abstract translation: 提供了用于针刺穿并用预定物质填充腔室的装置和方法,并且激光将所得到的针孔重新密封在装置中。 装置的针穿透和激光可重新密封部分可用针刺穿以形成穿过其的针孔,以通过针填充腔室,并且可激光重新密封以通过施加预定波长的激光辐射和对其进行动力来气密地密封针孔 。 针穿透和激光可再密封部分在其轴向方向上限定预定的壁厚,并且包括热塑性材料,其基本上防止在针穿透和退出针时从针穿透和激光可再密封部分形成释放到腔室中的颗粒。 热塑性塑料包括预定量的颜料,其允许热塑性塑料基本上吸收预定波长的激光辐射,基本上防止辐射通过其预定壁厚,并将形成在其针穿入区域中的针孔密封在 预定时间段。

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