公开(公告)号：US4578468A

公开(公告)日：1986-03-25

申请号：US593159

申请日：1984-03-26

Applicant: Guy T. Carter ,  Donald B. Borders ,  Joseph J. Goodman ,  David P. Labeda

Inventor： Guy T. Carter ,  Donald B. Borders ,  Joseph J. Goodman ,  David P. Labeda

IPC: A23K20/195 ,  A61K31/47 ,  A61P33/00 ,  A61P33/02 ,  C07D319/00 ,  C07D491/16 ,  C12P17/18 ,  C12R1/03 ,  C07D498/12

CPC classification number: C07D491/16 ,  A23K20/195 ,  C12P17/188 ,  C12R1/03

Abstract: Antibiotic LL-D42067.beta. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.

Abstract translation: 抗生素LL-D42067通过有氧发酵得到的微生物Actinomadura madurae亚种simaoensis NRRL 15734，可用作抗菌和抗寄生虫剂。

公开(公告)号：US4499075A

公开(公告)日：1985-02-12

申请号：US362002

申请日：1982-03-25

Applicant: May D. Lee ,  John H. Martin ,  Donald B. Borders ,  Raymond C. Yao ,  Raymond T. Testa

Inventor： May D. Lee ,  John H. Martin ,  Donald B. Borders ,  Raymond C. Yao ,  Raymond T. Testa

IPC: C12P1/06 ,  A61K35/00

CPC classification number: C12P1/06

Abstract: This invention relates to new polypeptide antibiotics designated LL-BO2964.alpha., LL-BO2964.beta., LL-BO2964.gamma., and a mixture thereof designated LL-BO2964, produced during microbiological fermentation, under controlled conditions, using a new strain of Streptomyces coeruleorubidus subspecies rubidus or a mutant thereof. The new antibiotics are active against a variety of microorganisms and are also useful in treating tuberculosis.