公开(公告)号：US12102086B2

公开(公告)日：2024-10-01

申请号：US18454855

申请日：2023-08-24

Applicant: XIAMEN UNIVERSITY

Inventor： Kejian Wang ,  Manyu Jiang ,  Fangyi Chen

IPC: A61K38/17 ,  A01N37/46 ,  A01P1/00 ,  A01P3/00 ,  A23K20/195 ,  A23K50/80 ,  C07K14/435

CPC classification number: A01N37/46 ,  A01P1/00 ,  A01P3/00 ,  A23K20/195 ,  A23K50/80 ,  A61K38/1767 ,  C07K14/43509

Abstract: An antimicrobial peptide Spampcin56-86from Scylla paramamosain is provided. A molecular formula of the antimicrobial peptide Spampcin56-86 is C154H256N54O33S3, and an amino acid sequence of the antimicrobial peptide Spampcin56-86 is shown in SEQ ID NO: 01.

公开(公告)号：US11951138B2

公开(公告)日：2024-04-09

申请号：US14773887

申请日：2014-03-13

Applicant: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)

Inventor： Itzhak Mizrahi ,  Elie Jami

IPC: A61K35/74 ,  A23K10/18 ,  A23K20/195 ,  A23K50/10 ,  A23K50/60 ,  A61K35/66 ,  C12N1/20 ,  C12Q1/6869 ,  C12Q1/689

CPC classification number: A61K35/74 ,  A23K10/18 ,  A23K20/195 ,  A23K50/10 ,  A23K50/60 ,  A61K35/66 ,  C12N1/20 ,  C12Q1/6869 ,  C12Q1/689 ,  C12Q2600/124

Abstract: A method of mimicking a phenotype of a first ruminating animal in a second ruminating animal is disclosed. The method comprises administering to the second ruminating animal a microbial composition comprising a plurality of microbes having a signature which is statistically significantly similar to the microbial signature of a rumen microbiome of the first ruminating animal, wherein the first and the second ruminating animal are of identical species, thereby mimicking the phenotype of the first ruminating animal in the second ruminating animal.

公开(公告)号：US20240058402A1

公开(公告)日：2024-02-22

申请号：US18278878

申请日：2021-06-15

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jong Soo JEON ,  Ji Eun KIM ,  Jun Ok MOON ,  Jong Pyo CHAE ,  Yu Jin KIM ,  Seung Eun LEE

IPC: A61K35/76 ,  A61P31/04 ,  A23K10/16 ,  A23K20/195

CPC classification number: A61K35/76 ,  A61P31/04 ,  A23K10/16 ,  A23K20/195

Abstract: The present application relates to a novel bacteriophage having Clostridium perfringens-specific bactericidal effect and an antibacterial composition comprising same, the novel bacteriophage CJ_CP_20-29 having Clostridium perfringens-specific bactericidal effect, and being superbly acid and heat resistant to allow wide use in antibiotics, feed and additives therefor, beverages and additives therefor, disinfectants, detergents, and the like to prevent or treat infectious diseases caused by Clostridium perfringens.

公开(公告)号：US20230181622A1

公开(公告)日：2023-06-15

申请号：US15991989

申请日：2018-05-29

Applicant: Scott Lowell Crain ,  David Wayne Farnum

Inventor： Scott Lowell Crain ,  David Wayne Farnum

IPC: A61K31/716 ,  A61K38/00 ,  A23K50/30 ,  A23K20/10 ,  A23K20/195 ,  A61K45/06 ,  A61K33/30 ,  A23K50/10 ,  A23K20/20 ,  A23K20/147 ,  A61K31/715

CPC classification number: A61K31/716 ,  A61K38/00 ,  A23K50/30 ,  A23K20/10 ,  A23K20/195 ,  A61K45/06 ,  A61K33/30 ,  A23K50/10 ,  A23K20/30 ,  A23K20/147 ,  A61K31/715

Abstract: Disclosed herein are compositions and methods for modulating a macrolide antimicrobial, modulating an immune function, increasing the effectiveness of an antibiotic, and/or increasing the number and effectiveness of alveolar macrophages in treating a vertebrate animal. The method comprises feeding to the animal a feed composition comprising (1, 3), (1, 6), beta-glucans and optionally mannans to increase the number of alveolar macrophage cells, and administering a macrolide antibiotic to the animal.

公开(公告)号：US20190202896A1

公开(公告)日：2019-07-04

申请号：US16300457

申请日：2017-05-19

Applicant: NOVOBIND LIVESTOCK THERAPEUTICS INC.

Inventor： Hamlet ABNOUSI

IPC: C07K16/12 ,  A61K9/00 ,  A61P31/04 ,  A23L33/18 ,  A23K20/147 ,  A23K20/195 ,  A23K50/75

CPC classification number: C07K16/1235 ,  A23K20/147 ,  A23K20/195 ,  A23K50/75 ,  A23L33/18 ,  A23V2002/00 ,  A61K9/0053 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/55 ,  A61K2039/552 ,  A61P31/04 ,  C07K2317/10 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/35 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/569 ,  C07K2317/64 ,  C07K2317/70 ,  C07K2317/94

Abstract: Described herein are methods and antibodies useful for reducing, eliminating, or preventing infection with a bacterial population in domestic animals or humans. Also described herein are antigens useful for targeting by heavy chain antibodies and VHH fragments for reducing a bacterial population in domestic animals or humans.

公开(公告)号：US20180340003A1

公开(公告)日：2018-11-29

申请号：US16054713

申请日：2018-08-03

Applicant: Akeso Biomedical, Inc.

Inventor： Dlawer Ala'Aldeen ,  Jafar Mahdavi ,  Panos Soultanas

IPC: C07F15/02 ,  A61K31/7036 ,  A01N37/44 ,  C09D5/14 ,  G02B1/04 ,  A61K45/06 ,  A61L12/08 ,  A61L2/22 ,  A61L2/18 ,  A61L2/00 ,  A01N37/36 ,  A01N37/10 ,  A61K31/295 ,  A61K31/197 ,  A61L2/16 ,  A01N59/16 ,  A23K50/75 ,  A23K20/195 ,  A23K20/20 ,  A23K50/10 ,  A23K50/30 ,  A23K50/60 ,  A61K31/198 ,  A23L33/10 ,  A23L33/16

CPC classification number: C07F15/025 ,  A01N37/10 ,  A01N37/36 ,  A01N37/44 ,  A01N59/16 ,  A23K20/195 ,  A23K20/30 ,  A23K50/10 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23L33/127 ,  A23L33/16 ,  A23V2002/00 ,  A61K31/197 ,  A61K31/198 ,  A61K31/295 ,  A61K31/7036 ,  A61K45/06 ,  A61L2/0088 ,  A61L2/16 ,  A61L2/18 ,  A61L2/22 ,  A61L12/08 ,  A61L2202/24 ,  C09D5/14 ,  G02B1/043

Abstract: A method of enhancing the growth of an animal, as well as treating or preventing antimicrobial infections is provided. The method includes causing the animal to ingest or absorb an effective amount of one or more Fe III complex compounds, including but not limited to Fe III complexes comprising ligands bound to the iron center such as amino acids or α-hydroxy acids. The compounds are also useful for inhibiting, reducing, or preventing biofilm formation or buildup on a surface; the treatment of, inhibition of growth of, and inhibition of colonization by, bacteria, both in biological and non-biological environments; disinfecting surfaces, potentiating the effects of antibiotics and other anti-microbial agents, and increasing the sensitivity of bacteria and other microorganisms, to anti-microbial agents are also provided.

公开(公告)号：US20180333450A1

公开(公告)日：2018-11-22

申请号：US15978397

申请日：2018-05-14

Applicant: SarTec Corporation

Inventor： Larry C. McNeff ,  Clayton V. McNeff

IPC: A61K36/886 ,  A61K36/8965 ,  A61K36/752 ,  A61K36/48 ,  A61K36/898 ,  A61K36/8964 ,  A61K36/77 ,  A61K31/20 ,  A61K31/215 ,  A61P31/04 ,  A23K20/195 ,  A23K20/158

CPC classification number: A61K36/886 ,  A23K10/30 ,  A23K20/10 ,  A23K20/158 ,  A23K20/195 ,  A23K50/10 ,  A61K31/20 ,  A61K31/215 ,  A61K36/48 ,  A61K36/73 ,  A61K36/752 ,  A61K36/77 ,  A61K36/82 ,  A61K36/88 ,  A61K36/8964 ,  A61K36/8965 ,  A61K36/898 ,  A61P31/04 ,  A61K2300/00

Abstract: Embodiments herein include a composition that can include a saponin composition including saponins and at least one medium chain fatty acid (MCFA) or ester or salt thereof. In an embodiment, the saponins and at least one MCFA present in the composition can work synergistically to prevent methanogenesis by bacteria. In another embodiment, a method of processing animal feed using the compositions herein is included. Other embodiments are also included herein.

公开(公告)号：US20180199573A1

公开(公告)日：2018-07-19

申请号：US15742606

申请日：2016-06-29

Applicant: VIRBAC CORPORATION

Inventor： Dan Coleman ,  Steve Standley

IPC: A01N43/90 ,  A61K47/46 ,  A23K20/163 ,  A23K20/195 ,  A23K50/40 ,  A23K50/42 ,  A23K20/158 ,  A61K47/44 ,  A61K47/38 ,  A61K47/26 ,  A61K47/10 ,  A61K31/7048 ,  A61K31/506 ,  A61K31/4985 ,  A61K9/00 ,  A23L29/00 ,  A23L29/30 ,  A23L27/30 ,  A23L27/26 ,  A23K20/121 ,  A23K20/105 ,  A61K9/14 ,  A61K9/20

CPC classification number: A01N43/90 ,  A23K10/20 ,  A23K20/105 ,  A23K20/121 ,  A23K20/158 ,  A23K20/163 ,  A23K20/195 ,  A23K40/25 ,  A23K50/40 ,  A23K50/42 ,  A23L27/26 ,  A23L27/30 ,  A23L29/03 ,  A23L29/04 ,  A23L29/30 ,  A23V2002/00 ,  A61K9/0056 ,  A61K9/146 ,  A61K9/2013 ,  A61K9/2054 ,  A61K31/4985 ,  A61K31/506 ,  A61K31/7048 ,  A61K47/10 ,  A61K47/26 ,  A61K47/38 ,  A61K47/44 ,  A61K47/46 ,  A61K2300/00

Abstract: A chewable composition, comprising:—at least one pharmaceutically active ingredient component;—solid components including:—at least one flavor;—at least one disintegrant including at least one non-starch disintegrant;—flowable components including:—a flowable oil;—at least one wetting agent other than water.

公开(公告)号：US20180147158A1

公开(公告)日：2018-05-31

申请号：US15879475

申请日：2018-01-25

Applicant: ADNANE REMMAL

Inventor： AHMED REDA CHAMI

IPC: A61K31/05 ,  A61K47/02 ,  A23K20/195 ,  A61K9/14 ,  A01N35/02 ,  A01N31/16 ,  A01N31/08 ,  A01N31/06 ,  A01N25/12 ,  A01N25/08 ,  A23K20/111 ,  A23K20/10 ,  A23K50/90 ,  A23K50/80 ,  A23K50/75 ,  A23K50/50 ,  A23K50/30 ,  A23K50/20 ,  A23K50/10 ,  A23K20/28 ,  A61K31/045

CPC classification number: A61K31/05 ,  A01N25/08 ,  A01N25/12 ,  A23K20/10 ,  A23K20/111 ,  A23K20/195 ,  A23K20/28 ,  A23K50/10 ,  A23K50/20 ,  A23K50/30 ,  A23K50/50 ,  A23K50/75 ,  A23K50/80 ,  A23K50/90 ,  A61K9/143 ,  A61K31/045 ,  A61K47/02 ,  Y02A40/818 ,  A01N31/06 ,  A01N31/08 ,  A01N31/16 ,  A01N35/02

Abstract: The invention relates to a food additive which includes at least one clay interspersed with volatile antimicrobial agents. Such an additive can be added to the feed of certain animals, in particular poultry and ruminants, in order to act as a growth promoter and to reduce the risks of infection, as well as the risks of intoxication by mycotoxins.

公开(公告)号：US09950018B2

公开(公告)日：2018-04-24

申请号：US15304489

申请日：2015-03-13

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Eun Mi Shin ,  Gi Duk Bae ,  Jae Won Kim

IPC: C12N7/00 ,  A61K35/76 ,  A23K20/195 ,  A23K20/10 ,  A01N63/00 ,  A23L2/52 ,  A61K9/00 ,  C11D3/38 ,  C11D3/48

CPC classification number: A61K35/76 ,  A01N63/00 ,  A23K20/10 ,  A23K20/195 ,  A23L2/52 ,  A23V2002/00 ,  A61K9/0053 ,  C11D3/381 ,  C11D3/48 ,  C12N7/00 ,  C12N2795/00021

Abstract: The present invention relates to a novel bacteriophage ΦCJ27 (KCCM11465P) and a composition containing the same as an active ingredient. Further, the present invention relates to a method for preventing and/or treating infective diseases caused by enterotoxic Escherichia coli (ETEC) of non-human animals using the ΦCJ27 (KCCM11465P) and the composition.