公开(公告)号：US20060116368A1

公开(公告)日：2006-06-01

申请号：US11288624

申请日：2005-11-29

Applicant: Raul Calvo ,  Wing Cheung ,  Mark Player

Inventor： Raul Calvo ,  Wing Cheung ,  Mark Player

IPC: C07D279/16 ,  C07D265/36 ,  A61K31/5415 ,  A61K31/538

CPC classification number: C07D413/14 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.

Abstract translation: 本发明涉及香草素受体VR1配体。 更具体地，本发明涉及作为VR1的有效调节剂的异异构酰胺，其可用于治疗和预防哺乳动物的疾病状况。

公开(公告)号：US20060014812A1

公开(公告)日：2006-01-19

申请号：US11177716

申请日：2005-07-08

Applicant: Mark Player ,  Richard Pottorf ,  Dionisios Rentzeperis ,  Dibyendu De

Inventor： Mark Player ,  Richard Pottorf ,  Dionisios Rentzeperis ,  Dibyendu De

IPC: A61K31/426 ,  A61K31/42 ,  A61K31/415 ,  A61K31/198 ,  A61K31/277

CPC classification number: A61K31/198 ,  A61K31/085 ,  A61K31/277 ,  A61K31/415 ,  A61K31/4152 ,  A61K31/42 ,  A61K31/426

Abstract: Therapeutic methods of using certain heterocyclic arylidene aryl ether compounds for treating diseases or disorders mediated through modulation of estrogen related receptor alpha are described.

Abstract translation: 描述了使用某些杂环亚芳基芳基醚化合物治疗通过调节雌激素相关受体α介导的疾病或病症的治疗方法。

公开(公告)号：US06912667B1

公开(公告)日：2005-06-28

申请号：US10094247

申请日：2002-03-08

Applicant: Andrew Mark Player ,  Eric Minghorng Su

Inventor： Andrew Mark Player ,  Eric Minghorng Su

IPC: G06F11/10 ,  H04J3/14 ,  H04L1/24

CPC classification number: H04L1/24 ,  H04J3/14 ,  H04J2203/006

Abstract: A system and method are provided for transporting FTFL messages in a G.709 network-connected simplex device. The method comprises: receiving messages from a first source in a digital wrapper frame format with overhead bytes in every frame; recovering FTFL information from the received message overhead bytes; and, selectively supplying modified FTFL information for transmit message overhead bytes to the first source. Recovering FTFL information from the received message overhead bytes includes recovering a 256 byte FTFL message, including a 128-byte forward message and a 128-byte backward message. Selectively supplying modified FTFL information for transmit message overhead bytes to the first source includes the substeps of: examining the received messages to determine errors; generating a backward message to report the determined errors; overwriting the received backward message with the generated backward message to create the modified FTFL information; and, in response to overwriting the received backward message with the generated backward message, sending a FTFL_status_out signal. Then, the method further comprises: transmitting messages to the first source with the modified FTFL information in response to the FTFL_status_out signal.

Abstract translation: 提供了一种在G.709网络连接的单工设备中传送FTFL消息的系统和方法。 该方法包括：以数字包装帧格式接收来自第一源的消息，每帧中开销字节; 从接收的消息开销字节恢复FTFL信息; 并且向第一源选择性地提供用于发送消息开销字节的修改的FTFL信息。 从接收到的消息开销字节恢复FTFL信息包括恢复包括128字节转发消息和128字节反向消息的256字节FTFL消息。 将传输消息开销字节的修改的FTFL信息选择性地提供给第一源包括以下子步骤：检查接收到的消息以确定错误; 产生反向消息来报告确定的错误; 用生成的反向消息覆盖所接收的反向消息以创建修改的FTFL信息; 并且响应于利用生成的反向消息重写所接收的反向消息，发送FTFL_status_out信号。 然后，该方法还包括：响应于FTFL_status_out信号，将具有修改的FTFL信息的消息发送到第一源。