Biccyclic compounds as GATA modulators
    2.
    发明授权
    Biccyclic compounds as GATA modulators 失效
    双环化合物作为GATA调节剂

    公开(公告)号:US07989463B2

    公开(公告)日:2011-08-02

    申请号:US12553694

    申请日:2009-09-03

    IPC分类号: A61K31/517

    摘要: Novel bicyclic compounds of the formula (I), stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. Additionally, methods of forming novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided: wherein R1, R2, m, and n are defined herein.

    摘要翻译: 提供式(I)的新型双环化合物,新型双环化合物的立体异构体和/或药学上可接受的盐,和/或新型双环化合物的立体异构体的药学上可接受的盐。 另外,提供了形成新型双环化合物的新型双环化合物,立体异构体和/或药学上可接受的盐的方法,和/或新型双环化合物的立体异构体的药学上可接受的盐:其中R1,R2,m和n为 本文定义。

    Melt-spun polysulfone semipermeable membranes and methods for making the same
    4.
    发明授权
    Melt-spun polysulfone semipermeable membranes and methods for making the same 失效
    熔融聚砜半透膜及其制备方法

    公开(公告)号:US07144505B2

    公开(公告)日:2006-12-05

    申请号:US10327564

    申请日:2002-12-20

    IPC分类号: B01D39/00 B01D39/14 B01D33/21

    摘要: The present invention provides, inter alia, a composition useful for producing a homogeneous, semipermeable membrane, the composition comprising a polysulfone semipermeable membrane, the polysulfone semipermeable membrane comprising a mixture of: an ultra-high-molecular-weight hydrophilic polymer, a polysulfone compound and a solvent for the polysulfone compound, and the polysulfone semipermeable membrane having a homogeneous structure such that the polysulfone semipermeable membrane has a substantially uniform structure. Another aspect of this invention discloses methods for fabricating semipermeable membranes by homogeneously mixing the composition, melting the composition, and melt-spinning the molten composition. Another aspect of the present invention includes homogeneous, melt-spun, semipermeable membranes useful for liquid separation processes, such as, but not limited to, microfiltration, ultrafiltration, dialysis, and reverse osmosis.

    摘要翻译: 本发明尤其提供了一种用于制备均匀的半透膜的组合物,该组合物包含聚砜半透膜,聚砜半透膜包含以下混合物:超高分子量亲水聚合物,聚砜化合物 和聚砜化合物的溶剂,聚砜半透膜具有均匀的结构,使得聚砜半透膜具有基本均匀的结构。 本发明的另一方面公开了通过均匀混合组合物,熔融组合物和熔融组合物熔融纺制制造半透膜的方法。 本发明的另一方面包括用于液体分离过程的均匀的熔纺的半透膜,例如但不限于微滤,超滤,透析和反渗透。