公开(公告)号：US20150126269A1

公开(公告)日：2015-05-07

申请号：US14089255

申请日：2013-11-25

Applicant: John Linden ,  Trey Watkins ,  Mark Rubin ,  Brian Bright

Inventor： John Linden ,  Trey Watkins ,  Mark Rubin ,  Brian Bright

IPC: A63F13/00

CPC classification number: A63F13/30 ,  A63F13/46 ,  A63F13/88

Abstract: A videogame playable on a traditional gaming platform has an associated metagame playable on a handheld “second screen” device. In some embodiments, a player's performance in the videogame affects the player's performance in the metagame.

Abstract translation: 在传统游戏平台上播放的视频游戏具有在手持式“第二屏幕”设备上可播放的相关联的元标记。 在一些实施例中，玩家在视频游戏中的表现影响玩家在元游戏中的表现。

公开(公告)号：US20140296088A1

公开(公告)日：2014-10-02

申请号：US14115327

申请日：2013-04-23

Applicant: Francesca Demichelis ,  Karl Garsha ,  Phillip C. Miller ,  Ray B. Nagle ,  Michael Otter ,  Gary Anthony Pestano ,  Mark Rubin

Inventor： Francesca Demichelis ,  Karl Garsha ,  Phillip C. Miller ,  Ray B. Nagle ,  Michael Otter ,  Gary Anthony Pestano ,  Mark Rubin

IPC: C12Q1/68 ,  G06F19/18

CPC classification number: C12Q1/6886 ,  C12Q1/6841 ,  C12Q2600/156 ,  G01N33/57407 ,  G16B20/00 ,  H01H35/146 ,  H01M2/34 ,  H01M2/345 ,  H01M2/347 ,  H01M2/348 ,  H01M2220/20

Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.

Abstract translation: 一般来说，目前公开的技术涉及癌症亚型的鉴定。 更具体地，该技术涉及使用多变量图像数据确定癌症和/或进展的分子驱动因素的方法，以及怀疑患有b癌症的生物样品的相同细胞中的原位分子标记物和形态特征的统计分析。 这种分析是在单次采集后并行获得分子和解剖形态数据进行的。 该分析将特定的形态学和分子标记与展示癌症的特定遗传驱动因子的已知样品进行比较。 该方法提供统计信息，可以增加对癌症特异性分子驱动因子的识别的信心。

公开(公告)号：US20090204455A1

公开(公告)日：2009-08-13

申请号：US12322211

申请日：2009-01-30

Applicant: Mark Rubin

Inventor： Mark Rubin

IPC: G06Q10/00

CPC classification number: G06Q10/06 ,  G06Q10/04 ,  G06Q10/06393 ,  G06Q40/00

Abstract: Systems and methods for providing an automated system for directly connecting people, jobs, and/or departments within a business with business operational elements for establishing performance-based compensation to align compensation with activities that improve business efficiencies and profitability, including identifying areas of a business for implementing changes in processes, human resources, metrics, and systems, wherein the identification is provided based upon generating a visual representation of a business based on the energy and information systems of the business, and by making those changes to improve the operating efficiency of the business.

Abstract translation: 提供一个自动化系统和方法，用于直接连接业务中的人员，工作和/或部门的业务运营要素，用于建立基于绩效的薪酬，以使薪酬与提高业务效率和盈利能力的活动相一致，包括确定业务领域 用于实施流程，人力资源，指标和系统的改变，其中基于基于业务的能量和信息系统生成业务的视觉表示来提供所述标识，并且通过进行这些改变来提高业务的操作效率 这生意。

公开(公告)号：US20090069865A1

公开(公告)日：2009-03-12

申请号：US12299043

申请日：2007-05-01

Applicant: Eyal Lasko ,  Shmuel Springer ,  Mark Rubin ,  Amit Dar

Inventor： Eyal Lasko ,  Shmuel Springer ,  Mark Rubin ,  Amit Dar

IPC: A61N1/36

CPC classification number: A61N1/36003 ,  A61B5/1038 ,  A61H3/00 ,  A61N1/0452 ,  A61N1/0484 ,  A61N1/36014 ,  G01L1/20 ,  H01H3/14 ,  H03K17/9625

Abstract: A gait modulation system including: (a) a sensor device including a sensor adapted for associating with at least one lower limb of the patient, the sensor for transducing at least one parameter related to a gait of the patient, so as to obtain gait data related to the gait, and (b) a muscle stimulator including: (i) an electrical stimulation circuit, the circuit adapted to supply an electrical stimulation output to an electrode array for performing functional electrical stimulation of at least one muscle of the lower limb, and (ii) a microprocessor, operatively connected to the at least one sensor, the microprocessor adapted for: receiving a stream of gait information based on the gait data; processing the gait information, and controlling the stimulation output based on the processing of the gait information, and wherein the microprocessor is further adapted to identify a failure in the stream of gait information, and to consequently control the electrical stimulation circuit to deliver a fail-safe stimulation output over a portion of a duration of the failure.

Abstract translation: 一种步态调制系统，包括：（a）传感器装置，其包括适于与患者的至少一个下肢相关联的传感器，所述传感器用于转导与患者的步态相关的至少一个参数，以便获得步态数据 和（b）肌肉刺激器，其包括：（i）电刺激电路，所述电路适于向电极阵列提供电刺激输出，用于对下肢的至少一个肌肉进行功能性电刺激， 以及（ii）可操作地连接到所述至少一个传感器的微处理器，所述微处理器适于：基于所述步态数据接收步态信息流; 处理步态信息，以及基于步态信息的处理来控制刺激输出，并且其中所述微处理器还适于识别所述步态信息流中的故障，并且因此控制所述电刺激电路以递送故障信息， 在故障持续时间的一部分时间内产生安全刺激输出。