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31.发明申请公开(公告)号：US20210361314A1
公开(公告)日：2021-11-25
申请号：US17391874
申请日：2021-08-02
Applicant: Penumbra, Inc.
Inventor： Scott Teigen , Steven Loisel , Stephen Pons , Ben Tompkins
IPC: A61B17/3203 , A61B17/22 , A61B17/34 , A61M1/00
Abstract: An aspiration thrombectomy system, comprising a vacuum source comprising a controllable vacuum valve, a pressure source comprising a controllable pressure valve, an aspiration catheter having a proximal end and a distal end, wherein the proximal end of the aspiration catheter comprises connection tubing having a lumen configured to accommodate fluid, and wherein the connection tubing acts as a common conduit for fluid communication between the aspiration catheter and the vacuum and pressure sources via the vacuum and pressure valves, respectively, and a controller configured to open and close the vacuum and vent valves in a predetermined cycle to change a level of vacuum at the distal end of the aspiration catheter and control flow in and out from the distal end of the catheter.
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32.发明申请公开(公告)号：US20210308358A1
公开(公告)日：2021-10-07
申请号：US17352596
申请日：2021-06-21
Applicant: PENUMBRA, INC.
Inventor： Karthik Raman , Colin Yee , Chia-Hung Sze , Arthur John Lockhart , David Barry
Abstract: Doxorubicin is extracted from blood using anionic material, such as a resin comprising sulfonated polystyrene divinylbenzene beads, and polyethersulfone membrane, or both. After exposing the resin and/or membrane to blood in order to remove doxorubicin therefrom, the doxorubicin maybe extracted from the resin and/or membrane by exposing the material to an extraction solution, sonicating the extraction solution to enhance release of the doxorubicin, and repeating the exposure and sonication in order to remove substantially all of doxorubicin from the resin.
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公开(公告)号：US10716590B2
公开(公告)日：2020-07-21
申请号：US15926357
申请日：2018-03-20
Applicant: Penumbra, Inc.
Inventor： Steven Loisel
Abstract: A system for intracranial access that includes a support assembly is described. The system includes a tubular probe shaft that may be advanced through a hole in the patient's skull. The tubular probe shaft houses a rotating element that cuts clot, and is connected to a vacuum source to aspirate clot fragments and blood from the site. The rotating element may have a bident shape.
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公开(公告)号：US20200214786A1
公开(公告)日：2020-07-09
申请号：US16823103
申请日：2020-03-18
Applicant: Penumbra, Inc.
Inventor： Steven Loisel
Abstract: A system for intracranial access that includes a support assembly is described. The support assembly has a hub and lobes surrounding a central aperture for introducing a sheathed core that can accommodate an endoscope and/or other devices. Some embodiments include a collar and a ring, each of which can be tightened to secure the sheathed core in place. An accessory device for use during intracranial aspiration procedures is described.
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公开(公告)号：US10588656B2
公开(公告)日：2020-03-17
申请号：US16006747
申请日：2018-06-12
Applicant: Penumbra, Inc.
Inventor： Nicole Trosper , Holly Sit , Kathleen Lockhart , Stephany Lai
IPC: A61B17/3207 , A61B17/00
Abstract: A target substance, such as a thrombus, is removed from a patient's body via minimally invasive technique. A catheter is maneuvered and positioned near the target substance. The catheter may have a soft, atraumatic tip constructed from a metallic backbone covered by a polymer. Target substances are drawn into the catheter via an aspiration source. Near the catheter's distal end, a blade and opposing surface are housed within the catheter, and the blade moves relative to the opposing surface within the catheter lumen in order to fragment the target substance. The substances are fragmented within the catheter into discreet and relatively uniform particles. The aspiration source, which helps ensnare target substances, also serves to evacuate the substance fragments from the patient's body.
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Patent Agency Ranking
公开(公告)号：US20180263646A1
公开(公告)日：2018-09-20
申请号：US15926357
申请日：2018-03-20
Applicant: Penumbra, Inc.
Inventor： Steven Loisel
Abstract: A system for intracranial access that includes a support assembly is described. The system includes a tubular probe shaft that may be advanced through a hole in the patient's skull. The tubular probe shaft houses a rotating element that cuts clot, and is connected to a vacuum source to aspirate clot fragments and blood from the site. The rotating element may have a bident shape.
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公开(公告)号：US09943321B2
公开(公告)日：2018-04-17
申请号：US14682893
申请日：2015-04-09
Applicant: Penumbra Inc.
Inventor： Henry Nita
IPC: A61B17/22 , A61B17/3207 , A61M25/10 , A61B18/14 , A61B18/00
CPC classification number: A61B17/22 , A61B17/320758 , A61B18/1492 , A61B2017/22001 , A61B2017/22067 , A61B2017/22078 , A61B2017/22079 , A61B2017/320775 , A61B2018/00208 , A61B2217/005 , A61B2218/007 , A61M25/104
Abstract: Methods and devices to remove thromboembolic material from the human body using rotational energy and aspiration are disclosed. A thromboembolic removal system includes an extraction device and drive unit. The extraction device is introduced to the treatment area and activated by the drive unit to separate, break apart, loosen or soften thromboembolic material and to facilitate its aspiration outside the patient.
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公开(公告)号：US20170360450A1
公开(公告)日：2017-12-21
申请号：US15691579
申请日：2017-08-30
Applicant: Penumbra, Inc.
Inventor： Ben Tompkins , Arani Bose , Delilah Hui , David Barry , Stephen Pons , Aleksander Leynov
CPC classification number: A61B17/12154 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12181 , A61B2017/00871 , A61B2017/12054 , A61B2017/1209
Abstract: Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.
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公开(公告)号：US09775621B2
公开(公告)日：2017-10-03
申请号：US15383241
申请日：2016-12-19
Applicant: Penumbra, Inc.
Inventor： Ben Tompkins , Arani Bose , Delilah Hui , David Barry , Stephen Pons , Aleksander Leynov
CPC classification number: A61B17/12154 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12181 , A61B2017/00871 , A61B2017/12054 , A61B2017/1209
Abstract: Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.
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公开(公告)号：US20170215902A1
公开(公告)日：2017-08-03
申请号：US15488349
申请日：2017-04-14
Applicant: Penumbra, Inc.
Inventor： Aleksander Leynov , David Barry , Vikas Gupta , Arani Bose
IPC: A61B17/221
CPC classification number: A61B17/221 , A61B17/22 , A61B2017/00526 , A61B2017/22034 , A61B2017/22044 , A61B2017/2215 , A61B2217/005 , A61F2/013 , A61M2025/1052 , Y10T29/49826
Abstract: A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, a delivery and aspiration catheter, an aspiration pump, a thromboembolic receiver, and a thromboembolic separator.
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