公开(公告)号：US20240103300A1

公开(公告)日：2024-03-28

申请号：US18508894

申请日：2023-11-14

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI ,  Pascal LOSER ,  Ben CROOK ,  Massimo PINAZZA ,  Jim NIEBANCK ,  James PHILLIPS ,  Stefan BAUER

IPC: G02C7/08 ,  G02C5/14 ,  G02C11/00

CPC classification number: G02C7/083 ,  G02C5/146 ,  G02C11/10 ,  G02C2200/08

Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.

公开(公告)号：US20230270700A1

公开(公告)日：2023-08-31

申请号：US17934945

申请日：2022-09-23

Applicant: Acucela Inc.

Inventor： Ryo KUBOTA ,  Nancy BOMAN ,  Claes BAVIK ,  Ian L. SCOTT

IPC: A61K31/166 ,  A61K31/137 ,  A61K31/135 ,  A61K9/00 ,  A61K9/50 ,  A61K31/19 ,  A61K31/195

CPC classification number: A61K31/166 ,  A61K31/137 ,  A61K31/135 ,  A61K9/0048 ,  A61K9/5078 ,  A61K31/19 ,  A61K31/195

Abstract: Described herein are methods for the treatment of an ophthalmic disease or disorder comprising the administration of non-retinoid visual cycle modulators.

公开(公告)号：US20230241410A1

公开(公告)日：2023-08-03

申请号：US18163376

申请日：2023-02-02

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Benjamin CROOK ,  Stefan BAUER ,  Philip M. BUSCEMI ,  Amitava GUPTA ,  Jonas GERMANN

IPC: A61N5/06

CPC classification number: A61N5/0622 ,  A61N2005/0648 ,  A61N2005/0651

Abstract: A wearer adjustable apparatus is configured for a wearer to view an object and adjust stimuli projected into the eye by adjusting the location of the projection optics, for example with movement of the projection optics relative to one or more components of a support such as an eyeglass frame. In some embodiments, the projection system comprises an adjustable retainer for the wearer to adjust first active projection elements coupled to a first support in front of a first eye in relation to second projection optics coupled to a second support in front of a second eye of the wearer. In some embodiments, the apparatus comprises oculars comprising the projection optics and corrective lenses configured for the wearer to adjust positions of the lenses and projection optics in front of the wearer's eyes in order to project therapeutic spots onto a desired location relative to the wearer's retinas.

公开(公告)号：US20230110912A1

公开(公告)日：2023-04-13

申请号：US18064422

申请日：2022-12-12

Applicant: ACUCELA INC.

Inventor： Christian OGGENFUSS ,  Karim HAROUD ,  Lukas SCHEIBLER ,  Matthias PFISTER ,  Urban SCHNELL ,  Stefan TROLLER ,  Ryo KUBOTA ,  Philip BUSCEMI

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/13

Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

公开(公告)号：US20230089006A1

公开(公告)日：2023-03-23

申请号：US18051804

申请日：2022-11-01

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Gordon Frederick MACCABEE ,  Ferry WIDJAJA ,  Amitava GUPTA

IPC: G02C11/00 ,  G02C7/04

Abstract: A contact lens may include a body of contact lens material extending between a first surface and a second surface. An electromechanical component may be supported in the contact lens material between the first surface and the second surface. A support comprising a plurality of pillars may be formed of the contact lens material and may extend from at least one of the first surface and the second surface to the electromechanical component.

公开(公告)号：US20230026753A1

公开(公告)日：2023-01-26

申请号：US17936263

申请日：2022-09-28

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI ,  Matthias PFISTER ,  Stephan WYDER ,  Amitava GUPTA

IPC: A61B3/10 ,  G01B9/02091

Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).

公开(公告)号：US20230020468A1

公开(公告)日：2023-01-19

申请号：US17757748

申请日：2020-09-02

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/12

Abstract: Improved optical coherence tomography systems and methods to measure retinal data are presented. The systems may be compact, provide in-home monitoring, and have automation to allow the patient to measure himself or herself.

公开(公告)号：US20220404638A1

公开(公告)日：2022-12-22

申请号：US17820738

申请日：2022-08-18

Applicant: ACUCELA INC.

Inventor： Philip M. BUSCEMI ,  Ryo KUBOTA

IPC: G02C7/04 ,  G02B27/01 ,  G02C7/14

Abstract: Systems, devices, apparatuses and methods for an active projection system that may be incorporated into spectacles, contact lenses or provided as an add-on layer to existing spectacles or lenses. The active projection system operates to generate a stimulus or stimuli for viewing by a person's eye. The stimulus or stimuli creates an image that is defocused in front of the person's retina and can assist in slowing or stopping the progression of myopia or other refractive errors in the person.

公开(公告)号：US20220304573A1

公开(公告)日：2022-09-29

申请号：US17647585

申请日：2022-01-10

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI ,  Matthias PFISTER ,  Stephan WYDER ,  Amitava GUPTA

IPC: A61B3/10 ,  G01B9/02091

Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).

公开(公告)号：US20220214564A1

公开(公告)日：2022-07-07

申请号：US17655496

申请日：2022-03-18

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Philip M. BUSCEMI ,  Amitava GUPTA ,  Stefan BAUER ,  Benjamin CROOK ,  Julien SAUVET

IPC: G02C7/08 ,  G02C7/06 ,  G02C7/14 ,  G02C7/10 ,  G02C7/02

Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.