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公开(公告)号：US20050137699A1
公开(公告)日：2005-06-23
申请号：US10982692
申请日：2004-11-05
申请人： Amr Salahieh , Hans Valencia , Brian Brandt , Claudio Argento , Ulrich Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight Morejohn , Tom Saul
发明人： Amr Salahieh , Hans Valencia , Brian Brandt , Claudio Argento , Ulrich Haug , Jean-Pierre Dueri , Daniel Hildebrand , Dwight Morejohn , Tom Saul
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/005 , A61F2220/0058 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a sheath to a vicinity of the heart valve; deploying the anchor from the sheath; expanding the anchor with a deployment tool comprising a plurality of actuation elements to contact tissue at an anchor site; and retrieving the anchor into the sheath. Another aspect of the invention provides apparatus including a sheath; a deployment tool comprising a plurality of anchor actuation elements; a replacement valve configured to be disposed within the sheath for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the sheath for delivery to the vicinity of the heart valve, to be deployed from the sheath, to be expanded by the deployment tool to contact tissue at an anchor site and to be retrieved back into the sheath after having been expanded.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以下步骤：血管内递送替代瓣膜和可膨胀锚固件，所述替换瓣膜和可扩张锚固件处于护套内的未膨胀构型至心脏瓣膜附近; 从护套部署锚; 使用包括多个致动元件的展开工具来扩展锚，以在锚定位置处接触组织; 并将锚固件收回到护套中。 本发明的另一方面提供了一种包括护套的装置; 包括多个锚致动元件的展开工具; 配置成设置在所述护套内用于输送到所述心脏瓣膜附近的置换瓣膜; 以及被构造成设置在所述护套内以用于输送到所述心脏瓣膜附近的可扩张锚，以从所述鞘部署，以由所述展开工具扩张以在锚定位置处接触组织并被回收到所述鞘中 在扩大后。
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32.发明申请公开(公告)号：US20050137693A1
公开(公告)日：2005-06-23
申请号：US10893143
申请日：2004-07-15
申请人： Ulrich Haug , Hans Valencia , Robert Geshlider , Tom Saul , Amr Salahieh , Dwight Morejohn
发明人： Ulrich Haug , Hans Valencia , Robert Geshlider , Tom Saul , Amr Salahieh , Dwight Morejohn
CPC分类号： A61F2/2415 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2230/0054 , A61F2250/0039
摘要： The present invention relates to methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an anchor to a vicinity of the heart valve, the anchor having a braid, and expanding the braid to a deployed configuration against the patient's tissue. The braid may be fabricated from a single strand of wire and/or may comprise at least one turn feature.
摘要翻译： 本发明涉及血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和锚固件血管内输送到心脏瓣膜附近，锚具具有编织物，并且将编织物扩展到针对患者组织的展开构型。 编织物可以由单股线制成和/或可以包括至少一个匝特征。
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公开(公告)号：US20050137692A1
公开(公告)日：2005-06-23
申请号：US10893131
申请日：2004-07-15
申请人： Ulrich Haug , Hans Valencia , Robert Geshlider , Tom Saul , Amr Salahieh , Dwight Morejohn
发明人： Ulrich Haug , Hans Valencia , Robert Geshlider , Tom Saul , Amr Salahieh , Dwight Morejohn
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2415 , A61F2/2427 , A61F2/2436 , A61F2210/0014 , A61F2230/0054 , A61F2230/0078 , A61F2250/0039
摘要： The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.
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公开(公告)号：US20050137689A1
公开(公告)日：2005-06-23
申请号：US10746285
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： A method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a catheter to a vicinity of the heart valve; deploying the anchor from the catheter; expanding the anchor to contact tissue at an anchor site; and retrieving the anchor into the catheter. The invention also includes an apparatus for endovascularly replacing a heart valve, including: a catheter; a replacement valve configured to be disposed within the catheter for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the catheter for delivery to a vicinity of the heart valve, to be deployed from the catheter, to be expanded to contact tissue at an anchor site and to be retrieved back into the catheter after having been expanded.
摘要翻译： 一种用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将导管内的未膨胀构造的置换瓣膜和可扩张锚固件输送到心脏瓣膜附近; 从导管部署锚杆; 扩大锚点以在锚点处接触组织; 并将锚固件取回到导管中。 本发明还包括用于血管内置换心脏瓣膜的装置，包括：导管; 配置成设置在所述导管内用于输送到所述心脏瓣膜附近的置换瓣膜; 以及被构造成设置在所述导管内用于输送到所述心脏瓣膜附近以从所述导管展开的可扩张锚，以被扩张以在锚固部位接触组织并且在扩张后被回收回到所述导管中 。
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公开(公告)号：US20050137687A1
公开(公告)日：2005-06-23
申请号：US10746240
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： Apparatus for endovascularly replacing a patient's heart valve. In some embodiments the apparatus includes an expandable anchor with a lip region and a skirt region; and a replacement valve, wherein the lip region and skirt region are configured for percutaneous expansion to engage leaflets of the heart valve. The invention is also a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of endovascularly delivering apparatus including an anchor having lip and skirt regions, and a replacement valve coupled to the anchor, to a vicinity of the heart valve in a collapsed delivery configuration; and expanding the apparatus such that leaflets of the heart valve are captured between the lip and skirt regions of the anchor.
摘要翻译： 用于血管内置换患者心脏瓣膜的装置。 在一些实施例中，该装置包括具有唇部区域和裙部区域的可扩张锚固件; 以及替换阀，其中所述唇部区域和裙部区域构造成用于经皮膨胀以接合所述心脏瓣膜的小叶。 本发明也是用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以折叠的输送配置将血管内递送设备包括具有唇缘和裙部区域的锚定器和连接到锚固器的置换瓣膜到心脏瓣膜附近的步骤; 并且扩张设备，使得心脏瓣膜的小叶被捕获在锚的唇缘和裙部区域之间。
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