公开(公告)号：US08494619B2

公开(公告)日：2013-07-23

申请号：US12781411

申请日：2010-05-17

申请人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

发明人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

IPC分类号： A61B5/0452

CPC分类号： A61N1/3627 ,  A61B5/04525 ,  A61B5/7264 ,  A61N1/371 ,  G06F19/00

摘要： In an example, a cardiac rhythm management system includes an implantable physiological data monitor, a processor, a memory, and a display. The implantable physiological data monitor can be configured to monitor a plurality of cardiac responses. The processor can be configured to classify the cardiac response into one of at least three classes including pace-dominant, fusion, and pseudo-fusion. The processor can also be configured to calculate statistical information regarding the classified cardiac responses. In this example, the pace-dominant, fusion, and pseudo-fusion classes correspond to a cardiac response resulting from a corresponding electrostimulation. The memory is configured to store the classified cardiac responses and calculated statistical information for future use by the processor or for display. The display is configured to display the statistical information stored in the memory for diagnostic and device programming purposes.

摘要翻译： 在一个示例中，心律管理系统包括可植入的生理数据监视器，处理器，存储器和显示器。 可植入生理数据监视器可被配置为监视多个心脏反应。 该处理器可被配置为将心脏反应分类为至少三个类别中的一个，包括步调主导，融合和伪融合。 处理器还可以被配置为计算关于分类的心脏反应的统计信息。 在这个例子中，脚步显性，融合和伪融合类对应于由相应的电刺激产生的心脏响应。 存储器被配置为存储分类的心脏响应和计算的统计信息以供将来由处理器使用或用于显示。 显示器被配置为显示存储在存储器中用于诊断和设备编程目的的统计信息。

公开(公告)号：US20100305646A1

公开(公告)日：2010-12-02

申请号：US12781411

申请日：2010-05-17

申请人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

发明人： Theodore J. Schulte ,  Yanting Dong ,  Shibaji Shome ,  Abhilash Patangay

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61B5/04525 ,  A61B5/7264 ,  A61N1/371 ,  G06F19/00

摘要： In an example, a cardiac rhythm management system includes an implantable physiological data monitor, a processor, a memory, and a display. The implantable physiological data monitor can be configured to monitor a plurality of cardiac responses. The processor can be configured to classify the cardiac response into one of at least three classes including pace-dominant, fusion, and pseudo-fusion. The processor can also be configured to calculate statistical information regarding the classified cardiac responses. In this example, the pace-dominant, fusion, and pseudo-fusion classes correspond to a cardiac response resulting from a corresponding electrostimulation. The memory is configured to store the classified cardiac responses and calculated statistical information for future use by the processor or for display. The display is configured to display the statistical information stored in the memory for diagnostic and device programming purposes.

摘要翻译： 在一个示例中，心律管理系统包括可植入的生理数据监视器，处理器，存储器和显示器。 可植入生理数据监视器可被配置为监视多个心脏反应。 该处理器可被配置为将心脏反应分类为至少三个类别中的一个，包括步调主导，融合和伪融合。 处理器还可以被配置为计算关于分类的心脏反应的统计信息。 在这个例子中，脚步显性，融合和伪融合类对应于由相应的电刺激产生的心脏响应。 存储器被配置为存储分类的心脏响应和计算的统计信息以供将来由处理器使用或用于显示。 显示器被配置为显示存储在存储器中用于诊断和设备编程目的的统计信息。

公开(公告)号：US08306622B2

公开(公告)日：2012-11-06

申请号：US12892378

申请日：2010-09-28

申请人： Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Yanting Dong

发明人： Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Yanting Dong

IPC分类号： A61N1/00

CPC分类号： A61N1/371 ,  A61N1/3627 ,  A61N1/3684

摘要： A method and device to detect and compare changes in atrial rate and morphology can be used to identify left atrial sense and capture, such as from a quadripolar or other lead located in or around the coronary sinus.

摘要翻译： 用于检测和比较心房率和形态变化的方法和装置可用于鉴定左心房感和捕获，例如来自位于冠状窦内或周围的四极或其他导联。

公开(公告)号：US20110098768A1

公开(公告)日：2011-04-28

申请号：US12892378

申请日：2010-09-28

申请人： Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Yanting Dong

发明人： Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Yanting Dong

IPC分类号： A61N1/365

CPC分类号： A61N1/371 ,  A61N1/3627 ,  A61N1/3684

摘要： A method and device to detect and compare changes in atrial rate and morphology can be used to identify left atrial sense and capture, such as from a quadripolar or other lead located in or around the coronary sinus.

摘要翻译： 用于检测和比较心房率和形态变化的方法和装置可用于鉴定左心房感和捕获，例如来自位于冠状窦内或周围的四极或其他导联。

公开(公告)号：US09993205B2

公开(公告)日：2018-06-12

申请号：US12818066

申请日：2010-06-17

申请人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

发明人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

IPC分类号： A61N1/08 ,  A61B5/00 ,  A61N1/37 ,  A61B5/0452

CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response, a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

公开(公告)号：US20120226328A1

公开(公告)日：2012-09-06

申请号：US13466431

申请日：2012-05-08

申请人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

发明人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

IPC分类号： A61N1/365 ,  A61N1/37

CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/3684

摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

摘要翻译： 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

公开(公告)号：US08116870B2

公开(公告)日：2012-02-14

申请号：US12214852

申请日：2008-06-23

申请人： Yanting Dong ,  Scott A. Meyer ,  Kevin John Stahlsberg

发明人： Yanting Dong ,  Scott A. Meyer ,  Kevin John Stahlsberg

IPC分类号： A61N1/368

CPC分类号： A61N1/3712 ,  A61N1/3684

摘要： Multi-chamber pacing may result in capture of one chamber, capture of multiple chambers, fusion, or non-capture. Approaches for detecting various capture conditions during multi-chamber pacing are described. Pacing pulses are delivered to left and right heart chambers during a cardiac cycle. A cardiac electrogram signal is sensed following the delivery of the pacing pulses. Left chamber capture only, right chamber capture only, and bi-chamber capture may be distinguished based on characteristics of the cardiac electrogram signal. Multi-chamber capture detection may be implemented using detection windows having dimensions of time and amplitude. The detection windows are associated with expected features, such as expected signal peaks, under a particular capture condition. The cardiac electrogram signal features are compared to detection windows to determine the capture condition.

摘要翻译： 多腔起搏可能导致一个腔室的捕获，多个腔室的捕获，融合或非捕获。 描述了在多室起搏期间检测各种捕获条件的方法。 在心动周期期间，起搏脉冲被传送到左心室和右心室。 在起搏脉冲输送之后感测心电图信号。 仅左室捕获，右室捕获，双室捕获可以基于心电图信号的特征来区分。 可以使用具有时间和幅度尺寸的检测窗来实现多室捕获检测。 检测窗口与特定捕获条件下的预期特征（例如期望的信号峰值）相关联。 将心电图信号特征与检测窗口进行比较以确定捕获条件。

公开(公告)号：US07979113B2

公开(公告)日：2011-07-12

申请号：US12435896

申请日：2009-05-05

申请人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

发明人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

IPC分类号： A61B5/04

CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/7217 ,  A61B5/7264

摘要： Methods and systems involve classifying the cardiac response to pacing using a multi-channel approach. Multiple cardiac response signals are sensed via multiple sense channels. Each sense channel comprises a distinct combination of electrodes and sensing circuitry. The cardiac response to the pacing pulse is classified based on the morphology of the cardiac response signals. Classifying the cardiac response involves discriminating between capture, fusion, non-capture, and non-capture with intrinsic activity.

摘要翻译： 方法和系统包括使用多通道方法对心脏起搏应答进行分类。 通过多个感测通道感测多个心脏反应信号。 每个感测通道包括电极和感测电路的不同组合。 基于心脏反应信号的形态对起搏脉搏的心脏反应进行分类。 分类心脏反应包括区分捕获，融合，非捕获和非捕获与内在活动。

公开(公告)号：US20090240301A1

公开(公告)日：2009-09-24

申请号：US12435896

申请日：2009-05-05

申请人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

发明人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

IPC分类号： A61N1/08

CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/7217 ,  A61B5/7264

摘要： Methods and systems involve classifying the cardiac response to pacing using a multi-channel approach. Multiple cardiac response signals are sensed via multiple sense channels. Each sense channel comprises a distinct combination of electrodes and sensing circuitry. The cardiac response to the pacing pulse is classified based on the morphology of the cardiac response signals. Classifying the cardiac response involves discriminating between capture, fusion, non-capture, and non-capture with intrinsic activity.

摘要翻译： 方法和系统包括使用多通道方法对心脏起搏应答进行分类。 通过多个感测通道感测多个心脏反应信号。 每个感测通道包括电极和感测电路的不同组合。 基于心脏反应信号的形态对起搏脉搏的心脏反应进行分类。 分类心脏反应包括区分捕获，融合，非捕获和非捕获与内在活动。

公开(公告)号：US20100256703A1

公开(公告)日：2010-10-07

申请号：US12818066

申请日：2010-06-17

申请人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

发明人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

IPC分类号： A61N1/08 ,  A61N1/362

CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response, a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

摘要翻译： 用于分类心脏起搏应答的方法和装置包括建立可再触发的心脏反应分类窗口。 在递送起搏脉冲之后建立第一心脏响应分类窗口。 起搏刺激后的心脏信号在第一分类窗口中被感测。 如果在第一分类窗口中检测到触发特性，则可以触发第二心跳响应分类。 如果建立第二分类窗口，则在第二分类窗口中感测到心脏信号。 基于心脏信号的特征来确定对起搏刺激的心脏反应。 可以将心脏反应确定为例如捕获的应答，非捕获响应，添加到固有搏动的非捕获响应以及融合/假融合搏动之一。