公开(公告)号：US07774064B2

公开(公告)日：2010-08-10

申请号：US10734599

申请日：2003-12-12

申请人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

发明人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

IPC分类号： A61N1/37

CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response; a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

摘要翻译： 用于分类心脏起搏应答的方法和装置包括建立可再触发的心脏反应分类窗口。 在递送起搏脉冲之后建立第一心脏响应分类窗口。 起搏刺激后的心脏信号在第一分类窗口中被感测。 如果在第一分类窗口中检测到触发特性，则可以触发第二心跳响应分类。 如果建立第二分类窗口，则在第二分类窗口中感测到心脏信号。 基于心脏信号的特征确定对起搏刺激的心脏反应。 心脏反应可以被确定为捕获的应答，非捕获的响应之一; 例如，添加到固有节拍的非捕获响应以及融合/假融合节拍。

公开(公告)号：US09993205B2

公开(公告)日：2018-06-12

申请号：US12818066

申请日：2010-06-17

申请人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

发明人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

IPC分类号： A61N1/08 ,  A61B5/00 ,  A61N1/37 ,  A61B5/0452

CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response, a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

公开(公告)号：US20100256703A1

公开(公告)日：2010-10-07

申请号：US12818066

申请日：2010-06-17

申请人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

发明人： Scott A. Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

IPC分类号： A61N1/08 ,  A61N1/362

CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response, a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

摘要翻译： 用于分类心脏起搏应答的方法和装置包括建立可再触发的心脏反应分类窗口。 在递送起搏脉冲之后建立第一心脏响应分类窗口。 起搏刺激后的心脏信号在第一分类窗口中被感测。 如果在第一分类窗口中检测到触发特性，则可以触发第二心跳响应分类。 如果建立第二分类窗口，则在第二分类窗口中感测到心脏信号。 基于心脏信号的特征来确定对起搏刺激的心脏反应。 可以将心脏反应确定为例如捕获的应答，非捕获响应，添加到固有搏动的非捕获响应以及融合/假融合搏动之一。

公开(公告)号：US20050131477A1

公开(公告)日：2005-06-16

申请号：US10734599

申请日：2003-12-12

申请人： Scott Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

发明人： Scott Meyer ,  Yanting Dong ,  Jeremy Maniak ,  Doug Birholz ,  John Voegele

IPC分类号： A61B5/04 ,  A61B5/0452 ,  A61N1/37

CPC分类号： A61B5/7264 ,  A61B5/04525 ,  A61B5/7217 ,  A61N1/371

摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response; a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

摘要翻译： 用于分类心脏起搏应答的方法和装置包括建立可再触发的心脏反应分类窗口。 在递送起搏脉冲之后建立第一心脏响应分类窗口。 起搏刺激后的心脏信号在第一分类窗口中被感测。 如果在第一分类窗口中检测到触发特性，则可以触发第二心跳响应分类。 如果建立第二分类窗口，则在第二分类窗口中感测到心脏信号。 基于心脏信号的特征确定对起搏刺激的心脏反应。 心脏反应可以被确定为捕获的应答，非捕获的响应之一; 例如，添加到固有节拍的非捕获响应以及融合/假融合节拍。

公开(公告)号：US20130013020A1

公开(公告)日：2013-01-10

申请号：US13618486

申请日：2012-09-14

申请人： Kevin John Stalsberg ,  Yanting Dong ,  Scott A. Meyer ,  John Michael Voegele ,  Derek Daniel Bohn ,  Eric Keith Enrooth ,  Clayton Scott Foster ,  David William Yost

发明人： Kevin John Stalsberg ,  Yanting Dong ,  Scott A. Meyer ,  John Michael Voegele ,  Derek Daniel Bohn ,  Eric Keith Enrooth ,  Clayton Scott Foster ,  David William Yost

IPC分类号： A61N1/37

CPC分类号： A61N1/371 ,  A61B5/0452 ,  A61B5/7203 ,  A61B5/7217 ,  A61B5/7264

摘要： Methods and systems for detecting noise in cardiac pacing response classification processes involve determining that a cardiac response classification is possibly erroneous if unexpected signal content is detected. The unexpected signal content may comprise signal peaks that have polarity opposite to the polarity of peaks used to determine the cardiac response to pacing. Fusion/noise management processes include pacing at a relatively high energy level until capture is detected after a fusion, indeterminate, or possibly erroneous pacing response classification is made. The relatively high energy pacing pulses may be delivered until capture is detected or until a predetermined number of paces are delivered.

摘要翻译： 用于检测心脏起搏反应分类过程中的噪声的方法和系统涉及如果检测到意外的信号内容，则确定心脏反应分类可能是错误的。 意想不到的信号内容可以包括具有与用于确定对起搏的心脏反应的峰的极性相反的极性的信号峰。 融合/噪声管理过程包括在相对高的能量级别进行起搏，直到在融合之后检测到捕获，不确定或可能错误的起搏响应分类。 可以递送相对高的能量起搏脉冲，直到检测到捕获或直到传送预定数量的步数。

公开(公告)号：US20120226328A1

公开(公告)日：2012-09-06

申请号：US13466431

申请日：2012-05-08

申请人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

发明人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

IPC分类号： A61N1/365 ,  A61N1/37

CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/3684

摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

摘要翻译： 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

公开(公告)号：US20120165895A1

公开(公告)日：2012-06-28

申请号：US13411852

申请日：2012-03-05

申请人： Yanting Dong ,  Scott A. Meyer ,  Kevin John Stalsberg

发明人： Yanting Dong ,  Scott A. Meyer ,  Kevin John Stalsberg

IPC分类号： A61N1/365 ,  A61N1/37

CPC分类号： A61N1/371 ,  A61B5/04525

摘要： Cardiac devices and methods discriminate non-captured intrinsic beats during evoked response detection and classification by comparing the features of a post-pace cardiac signal with expected features associated with a non-captured response with intrinsic activation. Detection of a non-captured response with intrinsic activation may be based on the peak amplitude and timing of the cardiac signal. The methods may be used to discriminate between a fusion or capture beat and a non-captured intrinsic beat. Discriminating between possible cardiac responses to the pacing pulse may be useful, for example, during automatic capture verification and/or a capture threshold test.

摘要翻译： 心脏装置和方法通过将后期心脏信号的特征与与未捕获的应答相关联的预期特征与内在激活进行比较来区分诱发反应检测和分类期间的非捕获固有搏动。 利用内在激活的非捕获响应的检测可以基于心脏信号的峰值振幅和定时。 该方法可以用于区分融合或捕获节拍和未捕获的固有节拍。 对起搏脉冲的可能的心脏反应之间的区分可能是有用的，例如在自动捕获验证和/或捕获阈值测试期间。

公开(公告)号：US08116870B2

公开(公告)日：2012-02-14

申请号：US12214852

申请日：2008-06-23

申请人： Yanting Dong ,  Scott A. Meyer ,  Kevin John Stahlsberg

发明人： Yanting Dong ,  Scott A. Meyer ,  Kevin John Stahlsberg

IPC分类号： A61N1/368

CPC分类号： A61N1/3712 ,  A61N1/3684

摘要： Multi-chamber pacing may result in capture of one chamber, capture of multiple chambers, fusion, or non-capture. Approaches for detecting various capture conditions during multi-chamber pacing are described. Pacing pulses are delivered to left and right heart chambers during a cardiac cycle. A cardiac electrogram signal is sensed following the delivery of the pacing pulses. Left chamber capture only, right chamber capture only, and bi-chamber capture may be distinguished based on characteristics of the cardiac electrogram signal. Multi-chamber capture detection may be implemented using detection windows having dimensions of time and amplitude. The detection windows are associated with expected features, such as expected signal peaks, under a particular capture condition. The cardiac electrogram signal features are compared to detection windows to determine the capture condition.

摘要翻译： 多腔起搏可能导致一个腔室的捕获，多个腔室的捕获，融合或非捕获。 描述了在多室起搏期间检测各种捕获条件的方法。 在心动周期期间，起搏脉冲被传送到左心室和右心室。 在起搏脉冲输送之后感测心电图信号。 仅左室捕获，右室捕获，双室捕获可以基于心电图信号的特征来区分。 可以使用具有时间和幅度尺寸的检测窗来实现多室捕获检测。 检测窗口与特定捕获条件下的预期特征（例如期望的信号峰值）相关联。 将心电图信号特征与检测窗口进行比较以确定捕获条件。

公开(公告)号：US07979113B2

公开(公告)日：2011-07-12

申请号：US12435896

申请日：2009-05-05

申请人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

发明人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

IPC分类号： A61B5/04

CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/7217 ,  A61B5/7264

摘要： Methods and systems involve classifying the cardiac response to pacing using a multi-channel approach. Multiple cardiac response signals are sensed via multiple sense channels. Each sense channel comprises a distinct combination of electrodes and sensing circuitry. The cardiac response to the pacing pulse is classified based on the morphology of the cardiac response signals. Classifying the cardiac response involves discriminating between capture, fusion, non-capture, and non-capture with intrinsic activity.

摘要翻译： 方法和系统包括使用多通道方法对心脏起搏应答进行分类。 通过多个感测通道感测多个心脏反应信号。 每个感测通道包括电极和感测电路的不同组合。 基于心脏反应信号的形态对起搏脉搏的心脏反应进行分类。 分类心脏反应包括区分捕获，融合，非捕获和非捕获与内在活动。

公开(公告)号：US20090240301A1

公开(公告)日：2009-09-24

申请号：US12435896

申请日：2009-05-05

申请人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

发明人： Yanting Dong ,  Scott A. Meyer ,  Qingsheng Zhu

IPC分类号： A61N1/08

CPC分类号： A61N1/371 ,  A61B5/04525 ,  A61B5/7217 ,  A61B5/7264

摘要： Methods and systems involve classifying the cardiac response to pacing using a multi-channel approach. Multiple cardiac response signals are sensed via multiple sense channels. Each sense channel comprises a distinct combination of electrodes and sensing circuitry. The cardiac response to the pacing pulse is classified based on the morphology of the cardiac response signals. Classifying the cardiac response involves discriminating between capture, fusion, non-capture, and non-capture with intrinsic activity.

摘要翻译： 方法和系统包括使用多通道方法对心脏起搏应答进行分类。 通过多个感测通道感测多个心脏反应信号。 每个感测通道包括电极和感测电路的不同组合。 基于心脏反应信号的形态对起搏脉搏的心脏反应进行分类。 分类心脏反应包括区分捕获，融合，非捕获和非捕获与内在活动。