公开(公告)号：US11779702B2

公开(公告)日：2023-10-10

申请号：US16621289

申请日：2018-08-28

Applicant: BAYER HEALTHCARE LLC

Inventor： William Barone ,  Michael Spohn ,  Chelsea Marsh ,  Michael McDermott ,  John Volkar

IPC: A61M5/168 ,  A61M5/00 ,  A61M5/14 ,  A61M5/145 ,  A61M5/142 ,  G21C7/10 ,  G21C7/24 ,  G21C1/08 ,  G21C3/07 ,  G21C3/328 ,  G21C11/08 ,  C23C30/00

CPC classification number: A61M5/16827 ,  A61M5/007 ,  A61M5/1408 ,  A61M5/14546 ,  A61M5/14566 ,  A61M5/16854 ,  G21C7/10 ,  G21C7/24 ,  A61M2005/14208 ,  A61M2205/3341 ,  C23C30/00 ,  G21C1/08 ,  G21C3/07 ,  G21C3/328 ,  G21C11/08

Abstract: A method for dynamic pressure control during a multiphase injection is described wherein the pressures of fluids in the various reservoirs of a fluid delivery system are controlled to provide desired fluid delivery parameters. The methods include advancing the first drive member to expel the first fluid from the first reservoir into a conduit, wherein the fluid is pressurized to a first fluid pressure; measuring the first fluid pressure to provide a target value; while the second reservoir is in fluid isolation from the conduit, advancing or retracting the second drive member to increase or decrease the fluid pressure of the second fluid in the second reservoir to the target value; placing the second reservoir in fluid communication with the conduit; and advancing the second drive member to expel the second fluid from the second reservoir into the conduit.

公开(公告)号：US20230310758A1

公开(公告)日：2023-10-05

申请号：US18328564

申请日：2023-06-02

Applicant: Bayer Healthcare LLC

Inventor： Kevin Cowan ,  Michael Spohn ,  Michael McDermott

IPC: A61M5/36 ,  A61M5/00 ,  A61M5/145 ,  A61M5/315 ,  G01F23/02

CPC classification number: A61M5/365 ,  A61M5/007 ,  A61M5/1456 ,  A61M5/14546 ,  A61M5/315 ,  G01F23/02 ,  A61M5/3134

Abstract: A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging processing techniques and systems are also provided to determine various injection parameters and to verify the type and certain properties of fluid that is present within a syringe.

公开(公告)号：US20230285733A1

公开(公告)日：2023-09-14

申请号：US18019939

申请日：2021-08-12

Applicant: Bayer HealthCare LLC

Inventor： Kevin Cowan ,  Michael Spohn ,  Arthur Uber, III ,  John Haury ,  Joseph Kent

IPC: A61M39/08 ,  A61M39/20 ,  A61M39/24 ,  A61M5/31

CPC classification number: A61M39/08 ,  A61M39/20 ,  A61M39/24 ,  A61M5/3146 ,  A61M2039/242

Abstract: A prime tube includes a sidewall defining an internal chamber having an expandable volume, a connecter associated with a proximal end of the sidewall and configured to reversibly engage an outlet of a fluid reservoir containing a medical fluid, and a closure associated with a distal end of the sidewall, the closure permeable to air and substantially impermeable to the medical fluid. The expandable volume of the internal chamber is configured to increase as the medical fluid enters the internal chamber.

公开(公告)号：US11577022B2

公开(公告)日：2023-02-14

申请号：US16713335

申请日：2019-12-13

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  Barry Tucker ,  Arthur Uber, III ,  Edward Rhinehart ,  James Neill ,  Glen Williams ,  Michael Spohn

IPC: A61M5/145 ,  A61M5/14 ,  A61M5/00

Abstract: A syringe includes a barrel having a distal end, a proximal end, and a sidewall extending therebetween along a longitudinal axis. At least one engagement member protrudes from a terminal portion of the sidewall in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end. The at least one engagement member is configured for engagement with a locking mechanism of a fluid injector to releasably lock the syringe with the fluid injector. A taper of the at least one engagement member is configured to rotationally guide the syringe into alignment with the locking mechanism and axially eject the syringe upon rotation of the syringe. The locking mechanism operatively engages the at least one engagement member regardless of an orientation of the syringe about the longitudinal axis relative to the injector.

公开(公告)号：US20220339350A1

公开(公告)日：2022-10-27

申请号：US17863525

申请日：2022-07-13

Applicant: Bayer Healthcare LLC

Inventor： Michael Spohn ,  Kevin Cowan ,  Barry Tucker ,  Michael McDermott

IPC: A61M5/145 ,  A61M5/00

Abstract: A pressure jacket configured for connecting to an injector head of a fluid injector has an open distal end, an open proximal end, and a sidewall defining a throughbore extending between the distal end and the proximal end along a longitudinal axis. The throughbore is configured for receiving at least a portion of a syringe. The pressure jacket has at least one syringe retaining element positioned at least partially within the throughbore. The at least one syringe retaining element is configured for engaging at least a portion of the syringe during pressurized delivery of fluid from the syringe to prevent or limit a distal movement of the syringe relative to the pressure jacket.

公开(公告)号：US11207462B2

公开(公告)日：2021-12-28

申请号：US16341205

申请日：2017-10-16

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  Michael Spohn ,  Adam Steege ,  Jessie Delgado ,  Keith Lipford ,  Chet Larrow ,  Mariano Mumpower ,  Danica Gordon

IPC: A61M5/145 ,  A61M5/00 ,  A61M5/14 ,  A61M5/24 ,  A61M5/315

Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and radially movable relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are engaged with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.

公开(公告)号：US20210361875A1

公开(公告)日：2021-11-25

申请号：US16965865

申请日：2019-02-05

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  Michael Spohn ,  Michael Swantner ,  James Mierzwiak ,  David Berry ,  Barry Tucker ,  Arthur Uber, III

IPC: A61M5/315

Abstract: A rolling diaphragm syringe for receiving a medical fluid therein, the rolling diaphragm syringe comprising a sidewall that is flexible and rolls upon itself when acted upon by the piston such that an outer surface of the sidewall is rolled in a radially inward direction as the piston is advanced from the proximal end to the distal end, and wherein at least a portion of an inner surface of the flexible sidewall comprises at least one surface texturization feature.

公开(公告)号：US20210220557A1

公开(公告)日：2021-07-22

申请号：US17270616

申请日：2019-08-27

Applicant: BAYER HEALTHCARE LLC

Inventor： Amy Chaya ,  Michael Spohn ,  Michael McDermott ,  William Barone

IPC: A61M5/168 ,  A61M5/14 ,  A61M5/142

Abstract: A fluid injector system includes a control device operatively associated with a first drive component configured to pressurize and inject a first fluid and a second drive component configured to pressurize and inject a second fluid. The control device includes at least one processor programmed or configured to: during a first phase of a multi-phase injection protocol, actuate at least the first drive component to inject the first phase; during the first phase of the injection protocol and prior to transitioning to a second phase of the injection protocol, actuate the second drive component to pressurize the second fluid relative to a pressure of the first fluid; and during the second phase of the injection protocol, actuate the second drive component to inject at least the second fluid so that a desired steady-state ratio of the first fluid and the second fluid in the second phase is reached.

公开(公告)号：US11013857B2

公开(公告)日：2021-05-25

申请号：US16314897

申请日：2017-07-05

Applicant: BAYER HEALTHCARE LLC

Inventor： Arthur E. Uber, III ,  Molly Bingaman ,  Gerald Callan ,  Kevin Cowan ,  Genevieve Jerome ,  Matthew Leroch ,  Daniel Moore ,  Ralph Schriver ,  Michael Spohn ,  Michael Swantner ,  Barry Tucker

IPC: A61M5/145 ,  A61M5/44

Abstract: A system for heating a medical fluid has at least one first fluid container for storing the fluid, a fluid injector having at least one second fluid container for receiving the fluid from the at least one first fluid container through a fluid path set, at least one heating element positioned in-line with the fluid path set between the at least one first fluid container and the at least one second fluid container of the fluid injector for heating the fluid to a pre-determined temperature as the fluid flows through at least one fluid path element, and a controller for controlling an output of the at least one heating element based on at least one of a property of the at least one heating element and a property of the fluid flowing through the at least one fluid path element.

公开(公告)号：US12239818B2

公开(公告)日：2025-03-04

申请号：US18560984

申请日：2022-02-25

Applicant: Bayer HealthCare LLC

Inventor： Richard Morton ,  Christopher Scutt ,  Michael Spohn ,  Randy Lee ,  Mikayla Ferchaw ,  Kevin Cowan ,  Patrick Campbell ,  Andrew Naples ,  William Barone ,  Christopher Capone ,  Curtis Pastor ,  Charles Lang ,  Michael Swantner

IPC: A61M5/145 ,  A61M5/00 ,  A61M5/14 ,  A61M5/168 ,  A61M5/36 ,  A61M5/48

Abstract: A fluid injector system includes at least one injector for pressurizing and delivering at least one fluid from at least one fluid reservoir, at least one fluid path section providing fluid communication between a bulk fluid reservoir and a syringe connected to the at least one injector, and at least one sensor arranged along the at least one fluid path section. The at least one sensor includes an emitter configured to emit light through the at least one fluid path section, and a detector configured to receive the light emitted through the at least one fluid path section and generate an electrical signal based on at least one property of the received light. The fluid injector system may further include at least one processor programmed or configured to determine, based on the electrical signal generated by the detector, at least one of an identity of the at least one fluid present in the fluid path section, a concentration of the at least one fluid in the fluid path section, and at least one property of the fluid path section.