Calibration for OCT-NIRAF multimodality probe

    公开(公告)号:US11147453B2

    公开(公告)日:2021-10-19

    申请号:US15724003

    申请日:2017-10-03

    Abstract: A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle α formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle α at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(α). The calibration factor g(α) is a function of the angle α calculated at two or more of the plurality of locations. The angle α is composed of a transversal angle αt and an axial angle αa.

    PRELOADED STERILE BAG
    32.
    发明申请

    公开(公告)号:US20200345440A1

    公开(公告)日:2020-11-05

    申请号:US16854366

    申请日:2020-04-21

    Abstract: A sterile bag for covering medical equipment comprises: a barrier section, a flexible body section, and an attaching section. The flexible body section has a tubular shape extending from a proximal end to a distal end thereof, and an outer surface, an inner surface, and an open end. The barrier section is coupled to the proximal end, and the attaching section is formed at the distal end of the flexible body section. The barrier section is a rigid or semirigid component which attaches the sterile bag to a sterile component or to an unsterile component of the medical equipment in a pleaded or folded state. The flexible body section is configured to be deployed over the unsterile component so as to enclose within the inner surface thereof the unsterile component. The unsterile component is connectable to the sterile component through the central opening of the barrier section.

    OPTICAL PROBES WITH OPTICAL-CORRECTION COMPONENTS

    公开(公告)号:US20190223700A1

    公开(公告)日:2019-07-25

    申请号:US15879340

    申请日:2018-01-24

    Abstract: Some embodiments of a device comprise a sheath, a first light-guiding component, a second light-guiding component, an optical-focusing component, and an optical-correction component. The second light-guiding component and the optical-focusing component are aligned on an optical axis. Also, the optical-correction component does not directly contact the optical-focusing component, and the optical-correction component is not positioned on the optical axis.

    Crosstalk elimination or mitigation in optical coherence tomography

    公开(公告)号:US10323926B2

    公开(公告)日:2019-06-18

    申请号:US15629175

    申请日:2017-06-21

    Inventor: Badr Elmaanaoui

    Abstract: One or more devices, systems, methods and storage mediums for performing optical coherence tomography (OCT) while reducing and/or eliminating crosstalk noise are provided. Examples of such applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Preferably, the OCT devices, systems methods and storage mediums include or involve a method, such as, but not limited to, a complex conjugate method or a shift method, for handling the crosstalk noise in a way to mitigate or eliminate the noise from an image field of view. For example, a reference reflection or reference arm may be positioned or re-positioned in the image field of view at different locations depending on the crosstalk noise mitigation method being employed.

    OPTICAL DELAY LINE FOR COHERENCE IMAGING
    37.
    发明申请

    公开(公告)号:US20190086192A1

    公开(公告)日:2019-03-21

    申请号:US16119818

    申请日:2018-08-31

    Inventor: Badr Elmaanaoui

    Abstract: An optical coherence tomography (OCT) system comprises an interferometer configured to generate interference light based on interference between a reference beam and a sample beam with which a sample has been irradiated. A detector operates to detect intensities of the interference light and/or one or more interference patterns; a processor is configured measure a signal falloff of the intensity of the interference light and/or the one or more interference patterns; and an optical delay line configured to adjust an optical path difference according to the signal falloff so as not substantially introduce artifacts to an image of the sample. In one embodiment, the optical delay line includes a main reflector consisting of a mirror and a Faraday rotator; the Faraday rotator is placed between the n and n+1 coherence revival modes of the interferometer, where n is greater than or equal to 1.

    Methods and systems for system self-diagnosis

    公开(公告)号:US12277731B2

    公开(公告)日:2025-04-15

    申请号:US17870681

    申请日:2022-07-21

    Inventor: Badr Elmaanaoui

    Abstract: One or more devices, systems, methods, and storage mediums for performing self-diagnosis using one or more imaging modalities are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Devices, systems, methods, and storage mediums may include or involve a method, such as, but not limited to, for determining status or health (such as optical health) of a rotary joint of an apparatus/system and/or of the apparatus/system. A device, system, method, or storage medium may perform self-diagnosis or diagnosis to minimize, reduce, and/or avoid optical failures, rotary joint failures, or apparatus/system failures and to have a robust method(s) of determining the health of the rotary joint and/or the apparatus or system.

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