公开(公告)号：US11147453B2

公开(公告)日：2021-10-19

申请号：US15724003

申请日：2017-10-03

申请人： Canon U.S.A., Inc.

发明人： Daisuke Yamada ,  Jeffrey Chen ,  Badr Elmaanaoui

IPC分类号： A61B5/00 ,  G01B9/02 ,  G01N21/64

摘要： A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle α formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle α at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(α). The calibration factor g(α) is a function of the angle α calculated at two or more of the plurality of locations. The angle α is composed of a transversal angle αt and an axial angle αa.

公开(公告)号：US20200337535A1

公开(公告)日：2020-10-29

申请号：US16926130

申请日：2020-07-10

申请人： Canon U.S.A., Inc.

发明人： Daisuke Yamada

IPC分类号： A61B1/00 ,  G02B6/38 ,  A61B1/07 ,  A61B5/00

摘要： A catheter system includes an electronic console; a catheter having a proximal end attachable to the console and a distal end configured to house therein an optical probe; an optical fiber configured to transmit from the console to the optical probe excitation radiation of a first wavelength, and configured to return to the console an optical response signal having a second wavelength longer than the first wavelength; a detector configured to detect intensity of the optical response signal; and a processor configured to determine, based on the detected intensity of the optical response signal, whether the catheter is properly connected to the console. The optical response signal is generated within the optical fiber itself in response to transmitting the excitation radiation therethrough. The optical response signal is an auto-fluorescence signal and/or Raman scattering signal generated from the optical fiber itself.

公开(公告)号：US11514603B2

公开(公告)日：2022-11-29

申请号：US16809027

申请日：2020-03-04

申请人： Canon U.S.A., Inc.

发明人： Mie Kunio ,  Daisuke Yamada ,  Badr Elmaanaoui

IPC分类号： G06T7/00 ,  G06T7/73 ,  A61B5/00 ,  A61B5/06 ,  G06T7/13 ,  G06T7/62 ,  G06T7/254

摘要： A method for processing an intravascular image including a plurality of image frames acquired during a pullback of an imaging catheter inserted into a vessel. The method includes obtaining positions of lumen borders detected in the intravascular image and positions of stent-struts detected in the intravascular image. Determining, at different positions in a range, a stent expansion value of the stent implanted in the vessel, based on the first information and the second information, wherein each image frame from image frames in which stent-struts are detected corresponds to a different position along the range. The method may also include displaying an image including positions of lumen borders and positions of the stent-struts detected and a first indicator indicating a level along the range, of the stent expansion value, with the image.

公开(公告)号：US11129520B2

公开(公告)日：2021-09-28

申请号：US16926130

申请日：2020-07-10

申请人： Canon U.S.A., Inc.

发明人： Daisuke Yamada

IPC分类号： A61B1/00 ,  G02B6/38 ,  A61B1/07 ,  A61B5/00

摘要： A catheter system includes an electronic console; a catheter having a proximal end attachable to the console and a distal end configured to house therein an optical probe; an optical fiber configured to transmit from the console to the optical probe excitation radiation of a first wavelength, and configured to return to the console an optical response signal having a second wavelength longer than the first wavelength; a detector configured to detect intensity of the optical response signal; and a processor configured to determine, based on the detected intensity of the optical response signal, whether the catheter is properly connected to the console. The optical response signal is generated within the optical fiber itself in response to transmitting the excitation radiation therethrough. The optical response signal is an auto-fluorescence signal and/or Raman scattering signal generated from the optical fiber itself.

公开(公告)号：US20190146163A1

公开(公告)日：2019-05-16

申请号：US16243934

申请日：2019-01-09

申请人： CANON U.S.A., INC.

发明人： Alexander Altshuler ,  Daisuke Yamada

IPC分类号： G02B6/42 ,  G02B6/38 ,  G02B6/32 ,  G02B6/36

摘要： A first optical axis of a first optical component is caused to be at a first angle with respect to a first precision surface of the first optical component. A second optical axis of a second optical component is aligned to be at a second angle to a second flat surface of the second optical component. The second angle is equal to or derived from the first angle. The first and second flat surfaces are caused to directly face each other to allow only sliding motion between the first and second flat surfaces. The sliding motion is performed between the first and second flat surfaces until the first and second optical axes are sufficiently collinear.

公开(公告)号：US20190099080A1

公开(公告)日：2019-04-04

申请号：US16148421

申请日：2018-10-01

申请人： CANON U.S.A., INC.

发明人： Mie Kunio ,  Daisuke Yamada ,  Yohei Minatoya

IPC分类号： A61B5/00 ,  A61F2/92 ,  A61B8/12

摘要： A method for processing an intravascular image including a plurality of image frames acquired during a pullback of an imaging catheter inserted into a vessel, the method including displaying on a graphical user interface (GUI) an image including detected results of lumen borders and at least one stent, the image including an evaluated stent expansion and an evaluated stent apposition determined from the intravascular image. The method also includes determining whether a modification to the detected results of the stent has been received by the GUI. Then, re-evaluating stent length, stent expansion and stent apposition when it is determined that the detected results of the stent has been modified via the GUI and displaying the re-evaluated stent expansion and the re-evaluated stent apposition on the GUI.

公开(公告)号：US20190099079A1

公开(公告)日：2019-04-04

申请号：US15724003

申请日：2017-10-03

申请人： Canon U.S.A., Inc.

发明人： Daisuke Yamada ,  Jeffrey Chen ,  Badr Elmaanaoui

IPC分类号： A61B5/00

摘要： A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle α formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle α at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(α). The calibration factor g(α) is a function of the angle α calculated at two or more of the plurality of locations. The angle α is composed of a transversal angle αt and an axial angle αa.

公开(公告)号：US20180003481A1

公开(公告)日：2018-01-04

申请号：US15617928

申请日：2017-06-08

申请人： Canon U.S.A. Inc. ,  The General Hospital Corporation

发明人： Daisuke Yamada ,  Guillermo J. Tearney

IPC分类号： G01B9/02 ,  A61B5/00

CPC分类号： G01B9/02091 ,  A61B5/0033 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/6852 ,  G01B9/02002 ,  G01B9/02044 ,  G01B9/0205 ,  G01B9/02051 ,  G01B9/02089

摘要： One or more devices, systems, methods and storage mediums for performing continuously, full range optical coherence tomography (OCT) without losing A-lines are provided. Examples of such applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes (e.g., common path probes), catheters, endoscopes, phase shift units (e.g., galvanometer scanner) and bench top systems. Preferably, the OCT devices, systems methods and storage mediums include or involve a phase shift device including at least a galvanometer scanner. The galvanometer scanner is preferably applied with or to a voltage with a triangle shape, the voltage having continuity or absolute constant frequency to obtain continuous images without losing any A-lines. The method(s) may include background subtraction, image shifting to compensate phase shifts and a DC noise reduction algorism.

公开(公告)号：US11707186B2

公开(公告)日：2023-07-25

申请号：US16898293

申请日：2020-06-10

申请人： Canon U.S.A., Inc.

发明人： Daisuke Yamada

IPC分类号： A61B1/04 ,  A61B1/015 ,  A61B1/313 ,  A61B1/045 ,  A61B1/00 ,  A61B5/00 ,  A61B1/07 ,  A61B1/06 ,  A61B90/00 ,  A61M5/00

CPC分类号： A61B1/043 ,  A61B1/0002 ,  A61B1/00009 ,  A61B1/00036 ,  A61B1/00126 ,  A61B1/015 ,  A61B1/045 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/07 ,  A61B1/3137 ,  A61B5/0035 ,  A61B5/0066 ,  A61B5/0071 ,  A61B2090/3735 ,  A61M5/007

摘要： One or more triggers, fluorescence or auto-fluorescence triggers, NIRAF triggers, methods of using triggers, fiber optic rotary joints (FORJ), free space beam combiners, OCT, SEE and/or fluorescence devices and systems for use therewith, methods of using and/or manufacturing same and storage mediums are provided. One or more embodiments using one or more triggers achieve structural compactness and/or high-speed acquisition while avoiding or reducing the need for high computational power. One or more embodiments use one or more triggers, one or more fluorescence triggers, one or more auto-fluorescence triggers, or NIRAF triggers, and/or one or more rotary joints, for performing pullback and/or image recording. Examples of optical applications that may involve the use of a trigger, fluorescence/auto-fluorescence trigger or NIRAF trigger, and/or a fiber optic rotary joint, include imaging, evaluating and characterizing/identifying biological objects or tissue, such as, but not limited to, for gastro-intestinal, otolaryngologic, cardio and/or ophthalmic applications.

公开(公告)号：US20210113098A1

公开(公告)日：2021-04-22

申请号：US17064435

申请日：2020-10-06

申请人： Canon U.S.A., Inc.

发明人： Daisuke Yamada

IPC分类号： A61B5/02 ,  A61B5/00 ,  A61B8/12 ,  A61B8/08 ,  G06N20/00

摘要： A method for intravascular image processing carries out steps of acquiring intravascular data of a portion of a lumen, determining a region of interest based on characteristics of the acquired data, determining an angle (orientation) for displaying an initial longitudinal view of the portion of the lumen based on the determined region of interest, and displaying the initial longitudinal view based on the determined angle and displaying a tomographic view of the portion of the lumen.