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![PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS](/abs-image/US/2011/12/01/US20110294826A1/abs.jpg.150x150.jpg)
公开(公告)号：US20110294826A1
公开(公告)日：2011-12-01
申请号：US12964841
申请日：2010-12-10
IPC分类号： A61K31/519 , A61P25/28 , A61P19/02 , A61P35/00 , A61P3/10 , A61P31/12 , A61P25/00 , A61P31/00 , A61P29/00 , A61P37/00 , A61P37/08 , C07D487/04 , A61P35/02
CPC分类号： C07D487/04
摘要： Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation.
摘要翻译： 本文描述的是吡咯并[2,3-d]嘧啶化合物，它们用作Janus Kinase（JAK）抑制剂，含有这些化合物的药物组合物及其制备方法。
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![1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position](/abs-image/US/2005/07/26/US06921823B2/abs.jpg.150x150.jpg)
32.发明授权1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position 失效在9位含有芳基砜的1,2,3,4,5,6-六氢吖庚因并[4,5-b]吲哚公开(公告)号：US06921823B2
公开(公告)日：2005-07-26
申请号：US10013858
申请日：2001-10-30
IPC分类号： A61K31/55 , A61P3/04 , A61P25/00 , A61P25/18 , A61P25/22 , A61P25/24 , C07C317/36 , C07C323/09 , C07D487/04 , C07D487/00
CPC分类号： C07D487/04 , C07C317/34 , C07C317/36 , C07C323/09
摘要： The present invention are substituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (X) and unsubstituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (XI) such as the compound of EXAMPLE 13 which are useful in treating depression, obesity and other CNS disorders.
摘要翻译： 本发明是取代的9-芳基砜-1,2,3,4,5,6-六氢吖庚因并[4,5-b]吲哚（X）和未取代的9-芳基砜-1,2,3,4,5,6 六氢吖庚因并[4,5-b]吲哚（XI），例如可用于治疗抑郁症，肥胖症和其他CNS疾病的实施例13的化合物。
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![1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position](/abs-image/US/2005/04/12/US06878823B2/abs.jpg.150x150.jpg)
33.发明授权1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position 失效在9位含有芳基砜的1,2,3,4,5,6-六氢吖庚因[4,5-b]吲哚公开(公告)号：US06878823B2
公开(公告)日：2005-04-12
申请号：US10022471
申请日：2001-10-30
IPC分类号： A61K31/55 , A61P3/04 , A61P25/00 , A61P25/18 , A61P25/22 , A61P25/24 , C07C317/36 , C07C323/09 , C07D487/04 , C07D223/12
CPC分类号： C07D487/04 , C07C317/34 , C07C317/36 , C07C323/09
摘要： The present invention are substituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (X) and unsubstituted 9-arylsulfone-1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles (XI) such as the compound of EXAMPLE 13 which are useful in treating depression, obesity and other CNS disorders.
摘要翻译： 本发明是取代的9-芳基砜-1,2,3,4,5,6-六氢吖庚因并[4,5-b]吲哚（X）和未取代的9-芳基砜-1,2,3,4,5,6 六氢吖庚因[4,5-b]吲哚（XI），例如可用于治疗抑郁症，肥胖症和其它中枢神经系统疾病的实施例13的化合物。
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公开(公告)号：US06579870B2
公开(公告)日：2003-06-17
申请号：US09877308
申请日：2001-06-08
申请人： Eric Jon Jacobsen , Stephen J. King
发明人： Eric Jon Jacobsen , Stephen J. King
IPC分类号： A61K3155
CPC分类号： C07D295/135 , C07D243/08
摘要： The present invention provides pharmaceutically active compounds useful for the treatment of diseases or disorders of the central nervous system.
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