利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

70 条记录 (耗时 0.029 秒)

    Oral delivery of discrete units
    31.
    发明授权
    Oral delivery of discrete units 有权
    口服离散单位

    公开(公告)号：US06210713B1

    公开(公告)日：2001-04-03

    申请号：US09513074

    申请日：2000-02-25

    申请人： Patrick S.-L. Wong ,  Howard B. Rosen ,  Nathan Roth ,  Phyllis I. Gardner

    发明人： Patrick S.-L. Wong ,  Howard B. Rosen ,  Nathan Roth ,  Phyllis I. Gardner

    IPC分类号： A61K914

    CPC分类号： A61K9/0092 ,  A47G21/183 ,  A61J7/0038

    摘要： The present invention is an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.

    摘要翻译： 本发明是一种口服活性剂递送系统和用于将活性剂制剂的离散单元递送给患者的方法。 含有活性剂制剂并具有流体通过的活性剂制剂保持剂的活性剂制剂室在第一端置于流体中，并在第二端置于患者口中。 当患者在房间的第二端上浸泡时，递送活性剂。

    Osmotic drug delivery devices with hydrophobic wall materials
    37.
    发明授权
    Osmotic drug delivery devices with hydrophobic wall materials 失效
    具有疏水壁材料的渗透性药物输送装置

    公开(公告)号：US5795591A

    公开(公告)日：1998-08-18

    申请号：US299867

    申请日：1994-09-01

    申请人： Eun Soo Lee ,  Scott A. Bura ,  Su Il Yum ,  Patrick S.-L. Wong ,  Felix Theeuwes

    发明人： Eun Soo Lee ,  Scott A. Bura ,  Su Il Yum ,  Patrick S.-L. Wong ,  Felix Theeuwes

    IPC分类号： A61M37/00 ,  A61K9/00 ,  A61K9/52 ,  A61K9/26

    CPC分类号： A61K9/0004

    摘要： Osmotically driven drug delivery devices with walls of porous hydrophobic material as the sole diffusion-limiting wall component are disclosed. Despite pores which are considerably larger than the molecular dimensions of osmotically active species in the interior of the device, despite pores which by their hydrophobic character do not permit the passage of liquid water, and despite the absence of a cellulosic semi-permeable membrane, the devices absorb water by osmosis without loss of the osmotically active species, and function in a manner analogous to osmotic pumps of the prior art. By permitting the use of hydrophobic substances as the wall material, the invention permits the device to be constructed entirely from biodegradable materials.

    摘要翻译： 公开了具有作为唯一扩散限制壁部件的多孔疏水材料壁的渗透驱动药物输送装置。 尽管孔远远大于装置内部的渗透活性物质的分子尺寸，尽管孔具有疏水性，但不允许液态水通过，尽管不存在纤维素半透膜， 装置通过渗透吸收水分而不损失渗透活性物质，并且以类似于现有技术的渗透泵的方式起作用。 通过允许使用疏水物质作为壁材料，本发明允许该装置完全由可生物降解的材料构成。