公开(公告)号：US20230310150A1

公开(公告)日：2023-10-05

申请号：US18207822

申请日：2023-06-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24 ,  A61F2/844 ,  A61F2/95

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/844 ,  A61F2002/9511 ,  A61F2/9517 ,  A61F2/2436

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US20230149674A1

公开(公告)日：2023-05-18

申请号：US18097365

申请日：2023-01-16

Applicant: Edwards Lifesciences Corporation

Inventor： Yair A. Neumann ,  Russell T. Joseph ,  Orna Popper ,  Izaak Rosen ,  Tiffany Diemtrinh Tran

IPC: A61M29/02 ,  A61M25/10 ,  A61F2/24

CPC classification number: A61M29/02 ,  A61M25/1002 ,  A61F2/2433 ,  A61M2025/1079 ,  A61M2025/1061 ,  A61M2025/1081

Abstract: Expandable sheaths and introducers are disclosed herein. In some examples, the expandable introducer includes an elongated body member, an inflatable balloon disposed between a proximal and distal end of the elongated body member, and an inflation lumen in fluid communication with the inflatable balloon. A portion of the balloon is sized and configured to pass through a distal opening of an expandable introducer sheath when in the deflated condition, and to dilate the distal end of the introducer sheath as the balloon expands from the deflated configuration to the inflated configuration. Methods of making and using the devices disclosed herein are also disclosed.

公开(公告)号：US20220287838A1

公开(公告)日：2022-09-15

申请号：US17829769

申请日：2022-06-01

Applicant: Edwards Lifesciences Corporation

Inventor： Oren Cohen ,  Tomer Saar ,  Elazar Levi Schwarcz ,  Ofir Witzman ,  Eitan Atias ,  Noam Miller ,  Eran Goldberg ,  Yair A. Neumann

IPC: A61F2/24 ,  A61F2/95

Abstract: A delivery apparatus for implanting a prosthetic valve includes a handle, a first shaft, a plurality of actuation shafts, and a control mechanism. The first shaft has one or more lumens extending from the first end portion to the second end portion. The actuation shafts each have a proximal end portion and a distal end portion, and the actuation shafts extend through the one or more lumens of the first shaft. The control mechanism is coupled to the actuation shafts and to the handle. The control mechanism is configured such that the actuation shafts can move axially relative to each other in a first operational mode and such that the actuation shafts can be moved axially simultaneously in a second operational mode. Additionally or alternatively, the first shaft can include a plurality of helical lumens configured for receiving the actuation shafts.

公开(公告)号：US20220257367A1

公开(公告)日：2022-08-18

申请号：US17732985

申请日：2022-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Yair A. Neumann ,  Oren Cohen ,  Khen Perlmutter ,  Eitan Atias ,  Noam Miller ,  Eran Goldberg ,  Anatoly Dvorsky ,  Tamir S. Levi ,  Haim Yushtein ,  Danny M. Garmahi ,  Ziv Yohanan ,  Michael Bukin ,  Noam Nir ,  Elena Sherman ,  Gideon Sagi

IPC: A61F2/24

Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.

公开(公告)号：US20220168125A1

公开(公告)日：2022-06-02

申请号：US17673601

申请日：2022-02-16

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Noa Axelrod Manela ,  Yair A. Neumann ,  Boaz Manash ,  David Maimon ,  Eyal Leiba ,  Ralph Schneider ,  Liron Tayeb

IPC: A61F2/966 ,  A61M25/00 ,  B29D23/00 ,  A61F2/24 ,  A61F2/95

Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.

公开(公告)号：US11318011B2

公开(公告)日：2022-05-03

申请号：US16389312

申请日：2019-04-19

Applicant: Edwards Lifesciences Corporation

Inventor： Yair A. Neumann

IPC: A61F2/24

Abstract: A frame for a prosthetic heart valve includes a plurality of strut members arranged to form an annular main body and coupled together by a plurality of pivot joints. The main body of the frame is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, and the frame has an inflow end and an outflow end. The frame further includes a plurality of leaflet clamps disposed on the exterior of the main body of the frame and coupled to the strut members. The leaflet clamps are movable between an open position corresponding to the collapsed configuration of the frame and a closed position corresponding to the expanded configuration of the frame. Motion of the main body of the frame between the collapsed configuration and the expanded configuration causes corresponding motion of the leaflet clamps between the open position and the closed position.

公开(公告)号：US20210282922A1

公开(公告)日：2021-09-16

申请号：US17337711

申请日：2021-06-03

Applicant: Edwards Lifesciences Corporation

Inventor： Hanoch Cohen-Tzemach ,  Tamir S. Levi ,  Yair A. Neumann ,  Tomer Saar ,  Gregory Rinberg

IPC: A61F2/24

Abstract: A radially expandable prosthetic valve can comprise an annular frame, at least one expansion mechanism and a cord. The annular frame can be radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The expansion mechanism can comprise a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location. The cord can extend at least partially along the expansion mechanism in a first direction, be reeved around a portion of the second member, and extend at least partially along the expansion mechanism in a second direction opposite the first direction. Applying a proximally directed force to a first portion of the cord can cause the second member to move relative to the first member, which can cause the frame to foreshorten axially and expand radially.

公开(公告)号：US20210085454A1

公开(公告)日：2021-03-25

申请号：US17114251

申请日：2020-12-07

Applicant: Edwards Lifesciences Corporation

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US10932903B2

公开(公告)日：2021-03-02

申请号：US16059913

申请日：2018-08-09

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Yair A. Neumann

IPC: A61F2/24

Abstract: Embodiments of an implantable prosthetic valve are disclosed. The valve can have an annular frame having a plurality of frame members and a skirt assembly. The skirt assembly can include a laminate having a fabric layer sandwiched between a first covering member and a second covering member. At least one surface of the fabric layer can be exposed at one or more windows in the second covering member. The skirt assembly can be coupled to the annular frame by a suture extending through the fabric layer at the one or more windows and around at least one of the plurality of frame members. Methods for making such an implantable prosthetic valve are also disclosed.

公开(公告)号：US20210015606A1

公开(公告)日：2021-01-21

申请号：US17063428

申请日：2020-10-05

Applicant: Edwards Lifesciences Corporation

Inventor： Oren Cohen ,  Ofir Witzman ,  Yair A. Neumann

IPC: A61F2/24

Abstract: A prosthetic valve delivery apparatus can comprise a handle, a gearbox, an input torque shaft and a plurality of output torque shafts. The input torque shaft can extend distally from the handle and can have a distal end portion operatively connected to the gearbox. The output torque shafts can be operatively connected to and extend distally from the gearbox. Rotation of the input torque shaft can cause rotation of the output torque shafts via the gear box.