公开(公告)号：US20250000644A1

公开(公告)日：2025-01-02

申请号：US18800580

申请日：2024-08-12

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Nir ,  Michael Bukin

IPC: A61F2/24

Abstract: An implantable device can include a radially expandable frame configured to move between a radially compressed state and a radially expanded state. The frame including a plurality of struts, at least one actuator mechanism configured to compress and expand the frame, and at least one locking mechanism coupled to the actuator mechanism. A first strut and a second strut can be pivotably coupled to one another at a common junction and configured to move toward one another as the frame is compressed and away from one another as the frame is expanded. The first and second struts can have first and second locking features that extend from respective longitudinal side edges of the struts. The locking mechanism can include a locking member configured to extend between and engage the first and second locking features when the frame is expanded to retain the frame in the radially expanded state.

公开(公告)号：US20240173129A1

公开(公告)日：2024-05-30

申请号：US18519557

申请日：2023-11-27

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Nir ,  Michael Bukin

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2002/9511 ,  A61F2250/0071

Abstract: A skirt for an implantable prosthetic device can include an annular fabric matrix radially expandable from a radially compressed configuration to a first diameter upon application of a radially outwardly directed force via the implantable prosthetic device, and a plurality of frangible restriction filaments embedded in the fabric matrix. Each restriction filament can have a selected maximum diameter different from that of at least one of the other restriction filaments, and each restriction filament can break when a radially outwardly directed force applied to the restriction filament exceeds a predetermined threshold.

公开(公告)号：US20230372093A1

公开(公告)日：2023-11-23

申请号：US18358845

申请日：2023-07-25

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Noam Nir ,  Tomer Saar ,  Tamir S. Levi

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2250/0069

Abstract: The present invention relates to implantable prosthetic devices, and more particularly, to 3D-shaped skirts having various coatings and/or configurations thereof.

公开(公告)号：US20230240843A1

公开(公告)日：2023-08-03

申请号：US18131325

申请日：2023-04-05

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Haim Yushtein ,  Noam Nir ,  Michael Bukin ,  David Maimon

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2403

Abstract: An implantable prosthetic device can include a radially expandable and compressible frame including an inflow end portion and an outflow end portion. The frame can include an expansion and locking mechanism comprising a member having a first set of lateral extensions disposed adjacent an outflow end and a second set of lateral extensions axially spaced from the first set, each lateral extension comprising a bore extending into the lateral extension. The frame can further comprise a commissure attachment member having a first set of arms each extending into a respective inner bore of the first set of lateral extensions and a second set of arms each extending into a respective inner bore of the second set of lateral extensions such that the commissure attachment member is restrained from movement relative to the expansion and locking mechanism in the radial and axial directions.

公开(公告)号：US20230190463A1

公开(公告)日：2023-06-22

申请号：US18110705

申请日：2023-02-16

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Nir

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2466

Abstract: An expansion and locking mechanism for a prosthetic valve and associated methods are disclosed. As one example, an expansion and locking mechanism for an implantable prosthetic device can include a first member coupled to a frame of the device and including at least one extension member extending in a circumferential direction and having a free end biased radially inward, into an interior of the first member and a second member coupled to the frame at a second location spaced apart from the first location, the second member extending at least partially inside the first member and comprising a plurality of radial extensions spaced apart from one another along a portion of a length of the second member, the plurality of radial extensions arranged in a first side of the second member that is arranged opposite a second side of the second member, the second side not including any radial extensions.

公开(公告)号：US20230157802A1

公开(公告)日：2023-05-25

申请号：US18094864

申请日：2023-01-09

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Carmel Peleg ,  Tomer Saar ,  Alexander Barash ,  David Maimon

IPC: A61F2/00 ,  A61F2/24 ,  A61F2/95

CPC classification number: A61F2/0095 ,  A61F2/24 ,  A61F2/9525 ,  A61F2/9522 ,  A61F2/9524

Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.

公开(公告)号：US20220323211A1

公开(公告)日：2022-10-13

申请号：US17852136

申请日：2022-06-28

Applicant: Edwards Lifesciences Corporation

Inventor： Sara Tzadok (formerly Haivatov) ,  Noam Nir

IPC: A61F2/24

Abstract: An assembly and associated method for a commissure of a prosthetic heart valve is disclosed. As one example, a method includes: forming a plurality of commissures with the plurality of leaflets, wherein each commissure is formed by: pairing a first commissure tab of a first leaflet with an adjacent, second commissure tab of a second leaflet, coupling a main body of a support strip to the first and second commissure tabs via primary sutures, folding a tab portion of the support strip over the main body, and coupling the tab portion of the support strip to the main body via secondary sutures, and for each commissure, securing the commissure to a respective support portion of a frame of the prosthetic heart valve.

公开(公告)号：US20220234306A1

公开(公告)日：2022-07-28

申请号：US17719262

申请日：2022-04-12

Applicant: Edwards Lifesciences Corporation

Inventor： Itai Pelled ,  Elena Sherman ,  Eran Goldberg ,  Kevin D. Rupp ,  Noam Nir

IPC: B29C65/00 ,  A61F2/24

Abstract: A prosthetic heart valve has a radially expandable and collapsible annular frame, the frame having an inflow end and an outflow end and defining a longitudinal axis along a lumen of the prosthetic heart valve when it is in the expanded configuration. A leaflet structure is positioned within the frame and secured thereto. The prosthetic heart valve also has a laminate sealing member including a plurality of layers heat-bonded together to encapsulate at least a portion of the frame. The laminate sealing member extends along the longitudinal axis in an upstream direction and doubles back toward the outflow end of the frame at a fold line to form a cuff, and an edge portion of the laminate sealing member is secured to a main portion of the laminate sealing member downstream of the fold line such that the cuff forms an inflow end of the laminate sealing member.

公开(公告)号：US20220023036A1

公开(公告)日：2022-01-27

申请号：US17496670

申请日：2021-10-07

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Elena Sherman ,  Noam Nir

IPC: A61F2/24

Abstract: A method of assembling a prosthetic heart valve comprises securing a suture loop having at least first and second windings to an outflow edge portion of an inner skirt. The first and second windings are arranged in a repeating pattern of figure-eight shape curves and each winding has a plurality of first sections attached to the outflow edge portion of the inner skirt and a plurality of second sections unattached to the inner skirt. The inner skirt is placed inside of an annular frame and the second sections of the first and second windings are placed over apices of an outflow end of the frame such that the second sections of the first and second windings reside outside of the frame. The second sections of the windings are inserted inwardly through openings in the frame and attached to selected locations on the inner skirt.

公开(公告)号：US10918473B2

公开(公告)日：2021-02-16

申请号：US16036190

申请日：2018-07-16

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Carmel Peleg ,  Tomer Saar ,  Alexander Barash ,  David Maimon

IPC: A61F2/24 ,  A61F2/00 ,  B21D39/04 ,  A61F2/95

Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.