公开(公告)号：US5840904A

公开(公告)日：1998-11-24

申请号：US863540

申请日：1997-05-27

Applicant: Gerhard Hamprecht ,  Eberhard Fuchs ,  Matthias Gerber ,  Helmut Walter ,  Karl-Otto Westphalen

Inventor： Gerhard Hamprecht ,  Eberhard Fuchs ,  Matthias Gerber ,  Helmut Walter ,  Karl-Otto Westphalen

IPC: A01N43/40 ,  A01N43/90 ,  C07D213/80 ,  C07D471/04 ,  C07D491/04 ,  C07D491/048

CPC classification number: C07D213/80 ,  A01N43/40 ,  C07D471/04 ,  C07D491/04

Abstract: Pyridine-2,3-dicarboximides of the general formula I ##STR1## where R.sup.1 is hydrogen, alkoxy or unsubstituted or substituted alkyl, cycloalkyl, alkenyl or alkynyl and R.sup.2, R.sup.3 and R.sup.4 are identical or different and are each hydrogen, halogen, cyano, unsubstituted or substituted alkyl, benzyl, cycloalkyl, alkenyl, alkynyl, alkoxy, phenoxy or phenylthio, a 5-membered or 6-membered heterocyclic radical having one or two hetero atoms selected from the group consisting of oxygen, sulfur and nitrogen, or unsubstituted or substituted phenyl, with the proviso that a) R.sup.2 is fluorine and R.sup.3 and R.sup.4 have the abovementioned general meanings or b) R.sup.3 is fluorine, chlorine, C.sub.1 -C.sub.3 -alkoxy, C.sub.2 -C.sub.5 -alkenyloxy, C.sub.2 -C.sub.5 -alkynyloxy, trifluoromathyl or cyano and R.sup.2 and R.sup.4 have the abovementioned general meanings or c) R.sup.4 is halogen or C.sub.1 -C.sub.3 -alkoxy, C.sub.2 -C.sub.5 -alkenyloxy or C.sub.2 -C.sub.5 alky-nyloxy and R.sup.2 and R.sup.3 have the abovementioned general meanings, with the exception of 5-chloropyridine-2,3-dicarboximide, and the environmentally compatible salts thereof.

Abstract translation: 通式I的吡啶-2,3-二羧酰亚胺其中R1是氢，烷氧基或未取代或取代的烷基，环烷基，烯基或炔基，R2，R3和R4相同或不同，各自为氢，卤素， 氰基，未取代或取代的烷基，苄基，环烷基，烯基，炔基，烷氧基，苯氧基或苯硫基，具有一个或两个选自氧，硫和氮的杂原子的5元或6元杂环基，或 未取代或取代的苯基，条件是a）R2是氟，R3和R4具有上述一般含义或b）R3是氟，氯，C1-C3-烷氧基，C2-C5-烯氧基，C2-C5-炔氧基， 三氟甲基或氰基，R2和R4具有上述一般含义或c）R 4是卤素或C 1 -C 3 - 烷氧基，C 2 -C 5 - 烯氧基或C 2 -C 5烷氧基，R 2和R 3具有上述一般含义， 5-氯吡啶-2,3-二甲酰亚胺，和环境 其相容的盐。

公开(公告)号：US5739324A

公开(公告)日：1998-04-14

申请号：US646279

申请日：1996-05-16

Applicant: Eberhard Fuchs ,  Tom Witzel

Inventor： Eberhard Fuchs ,  Tom Witzel

IPC: C07D223/10 ,  C07D201/08

CPC classification number: C07D201/08

Abstract: A process for preparing cyclic lactams by reacting amino carbonitriles with water in liquid phase in the presence of heterogeneous catalysts based on titanium dioxide, zirconium oxide, cerium oxide and aluminum oxide.

Abstract translation: PCT No.PCT / EP94 / 03781 Sec。 371日期：1996年5月15日 102（e）日期1996年5月16日PCT 1994年11月16日PCT公布。 出版物WO95 / 14664 日期：1995年6月1日在基于二氧化钛，氧化锆，氧化铈和氧化铝的非均相催化剂的存在下，使氨基腈与液相中的水反应制备环状内酰胺的方法。

公开(公告)号：US5693793A

公开(公告)日：1997-12-02

申请号：US707476

申请日：1996-09-05

Applicant: Josef Ritz ,  Eberhard Fuchs ,  Guido Voit ,  Gunther Achhammer ,  Rolf Fischer

Inventor： Josef Ritz ,  Eberhard Fuchs ,  Guido Voit ,  Gunther Achhammer ,  Rolf Fischer

IPC: C07C231/06 ,  C07C237/06 ,  C07C253/00 ,  C07C255/24 ,  C07D201/08 ,  C07D201/12 ,  C07D201/16

CPC classification number: C07D201/12 ,  C07D201/08

Abstract: A process for preparing caprolactam by cyclization of 6-aminocapronitrile in the presence of water at elevated temperature and in the presence or absence of a catalyst and a solvent, comprises a) removing from the cyclization reaction effluent ("reaction effluent I") caprolactam and all components boiling higher than caprolactam ("high boilers"), b) treating the high boilers of stage a) with phosphoric acid and/or polyphosphoric acid at from 200 to 350.degree. C. to obtain a reaction effluent II, and c) removing caprolactam formed and any 6-aminocapronitrile from reaction effluent II of stage b) to obtain separation from unconverted high boilers and acid used.

Abstract translation: 在高温存在下和在存在或不存在催化剂和溶剂的情况下，通过6-氨基己腈的环化制备己内酰胺的方法包括：a）从环化反应流出物（“反应流出物I”）中除去己内酰胺和 所有组分沸点高于己内酰胺（“高锅炉”），b）用磷酸和/或多磷酸在200至350℃下处理阶段a）的高锅炉以获得反应流出物II，和c）除去 己内酰胺和来自阶段b）的反应流出物II的任何6-氨基己腈得到与未转化的高锅炉和酸的分离。

公开(公告)号：US5679622A

公开(公告)日：1997-10-21

申请号：US361559

申请日：1994-12-22

Applicant: Gerhard Hamprecht ,  Eberhard Fuchs ,  Matthias Gerber ,  Helmut Walter ,  Karl-Otto Westphalen

Inventor： Gerhard Hamprecht ,  Eberhard Fuchs ,  Matthias Gerber ,  Helmut Walter ,  Karl-Otto Westphalen

IPC: A01N43/40 ,  A01N43/90 ,  C07D213/80 ,  C07D471/04 ,  C07D491/04 ,  C07D491/048

CPC classification number: C07D213/80 ,  A01N43/40 ,  C07D471/04 ,  C07D491/04

Abstract: Pyridine-2,3-dicarboximides of the general formula I ##STR1## where R.sup.1 is hydrogen, alkoxy or unsubstituted or substituted alkyl, cycloalkyl, alkenyl or alkynyl and R.sup.2, R.sup.3 and R.sup.4 are identical or different and are each hydrogen, halogen, cyano, unsubstituted or substituted alkyl, benzyl, cycloalkyl, alkenyl, alkynyl, alkoxy, phenoxy or phenylthio, a 5-membered or 6-membered heterocyclic radical having one or two hetero atoms selected from the group consisting of oxygen, sulfur and nitrogen, or unsubstituted or substituted phenyl, with the proviso that a) R.sup.2 is fluorine and R.sup.3 and R.sup.4 have the abovementioned general meanings or b) R.sup.3 is fluorine, chlorine, C.sub.1 -C.sub.3 -alkoxy, C.sub.2 -C.sub.5 -alkenyloxy, C.sub.2 -C.sub.5 -alkynyloxy, trifluoromethyl or cyano and R.sup.2 and R.sup.4 have the abovementioned general meanings or c) R.sup.4 is halogen or C.sub.1 -C.sub.3 -alkoxy, C.sub.2 -C.sub.5 -alkenyloxy or C.sub.2 -C.sub.5 -alkynyloxy and R.sup.2 and R.sup.3 have the abovementioned general meanings, with the exception of 5-chloropyridine-2,3-dicarboximide, and the environmentally compatible salts thereof.

Abstract translation: 通式I的吡啶-2,3-二羧酰亚胺其中R1是氢，烷氧基或未取代或取代的烷基，环烷基，烯基或炔基，R2，R3和R4相同或不同，各自为氢，卤素， 氰基，未取代或取代的烷基，苄基，环烷基，烯基，炔基，烷氧基，苯氧基或苯硫基，具有一个或两个选自氧，硫和氮的杂原子的5元或6元杂环基，或 未取代或取代的苯基，条件是a）R2是氟，R3和R4具有上述一般含义或b）R3是氟，氯，C1-C3-烷氧基，C2-C5-烯氧基，C2-C5-炔氧基， 三氟甲基或氰基，R 2和R 4具有上述一般含义或c）R 4是卤素或C 1 -C 3 - 烷氧基，C 2 -C 5 - 烯氧基或C 2 -C 5 - 炔氧基，并且R 2和R 3具有上述一般含义， 5-氯吡啶-2,3-二甲酰亚胺，和环境 其相容的盐。

公开(公告)号：US5646277A

公开(公告)日：1997-07-08

申请号：US646278

申请日：1996-05-16

Applicant: Eberhard Fuchs ,  Tom Witzel

Inventor： Eberhard Fuchs ,  Tom Witzel

IPC: C07D223/10 ,  C07D201/08

CPC classification number: C07D201/08

Abstract: Cyclic lactams are prepared by reacting amino carbonitriles with water in liquid phase in a fixed bed reactor in the presence of heterogeneous catalysts which have no soluble constituents under the reaction conditions.

Abstract translation: PCT No.PCT / EP94 / 03782 Sec。 371日期：1996年5月16日 102（e）日期1996年5月16日PCT 1994年11月15日PCT PCT。 公开号WO95 / 14665 日期1995年6月1日环己内酰胺是通过在固相床反应器中在液相中使氨基碳腈与水在反应条件下不溶于成分的非均相催化剂存在下制备的。

公开(公告)号：US5344983A

公开(公告)日：1994-09-06

申请号：US936084

申请日：1992-08-26

Applicant: Tom Witzel ,  Eberhard Fuchs ,  Franz Merger ,  Claus-Ulrich Priester

Inventor： Tom Witzel ,  Eberhard Fuchs ,  Franz Merger ,  Claus-Ulrich Priester

IPC: B01J23/40 ,  B01J23/755 ,  B01J27/10 ,  B01J27/125 ,  B01J27/18 ,  C07B61/00 ,  C07C209/48 ,  C07C211/09 ,  C07C209/00

CPC classification number: C07C209/48

Abstract: Process for preparing a pentane-1,5-diamine of the formula ##STR1## where R.sup.1 represents a variety of organic radicals including alkyl which can bear substituents such as hydroxyl, halogen, alkoxy, carbalkoxy, carboxyl, alkylamino, cycloalkyl or aryl, andR.sup.2 and R.sup.3 independently of one another, represent hydrogen or have the same meanings as R.sup.1 or together are a C.sub.4 -C.sub.7 -alkylene chain which is unsubstituted or substituted by one to five C.sub.1 -C.sub.4 -alkyl groups,which comprises:(a) reacting a .gamma.-cyanoketone of the formula ##STR2## where R.sup.1, R.sup.2 and R.sup.3 have the meanings given above, with excess ammonia in a first reaction space on an acidic heterogeneous catalyst at 20.degree.-150.degree. C. and 15-500 bar, and(b) hydrogenating the resulting reaction product in a second separate reaction space in the presence of excess ammonia on a cobalt, nickel or noble metal catalyst at 50.degree.-180.degree. C. and 30-500 bar.Novel pentane-1,5-diamines are obtained, in which R.sup.1 must contain at least two carbon atoms if R.sup.2 and R.sup.3 are both hydrogen. These new compounds containing two primary amine groups possess advantageous properties of lower volatility and also greater asymmetry (with different reactivity of the two amine functions). They provide useful curing agents for epoxides and act as improved components of polyamides.

Abstract translation: 制备式（I）的戊烷-1,5-二胺的方法，其中R 1表示各种有机基团，包括可以带有取代基的烷基，例如羟基，卤素，烷氧基，烷氧基，羧基，烷基氨基，环烷基或 芳基和R 2和R 3彼此独立地表示氢或具有与R 1相同的含义或一起是未被取代或被一至五个C 1 -C 4 - 烷基取代的C 4 -C 7亚烷基链，其包含：（ a）在20-150℃的酸性非均相催化剂的第一反应空间中使具有上述含义的式（Ia）的式（II）的γ-氰基酮与过量的氨反应，其中R1，R2和R3具有上述含义， 15-500巴，（b）在钴，镍或贵金属催化剂的存在下，在50-180℃和30-500巴下，在第二分开的反应空间中，使得到的反应产物氢化。 得到新的戊烷-1,5-二胺，如果R2和R3都是氢，其中R1必须含有至少两个碳原子。 这些含有两个伯胺基团的新化合物具有较低的挥发性和更大的不对称性（两种胺官能团的不同反应性）的有利特性。 它们为环氧化物提供有用的固化剂，并且作为聚酰胺的改进组分。