公开(公告)号：US5683326A

公开(公告)日：1997-11-04

申请号：US605920

申请日：1996-02-23

申请人： Eiji Inoue

发明人： Eiji Inoue

IPC分类号： F16H61/662 ,  F16H15/38 ,  B60K41/12

CPC分类号： F16H61/6648 ,  Y10T477/6243

摘要： This toroidal continuous variable transmission detects a deviation of the spool valve from its neutral position and performs a feedback control to prevent the transmission ratio from converging on other than the target transmission ratio or the speed change sequence from being started again. Further, the toroidal continuous variable transmission performs control so that as the actual transmission ratio approaches the target transmission ratio, the transmission speed decreases in order to prevent an overshoot of the speed change control. When the difference between the actual transmission ratio and the target transmission ratio is smaller than a specified value, the output signals to the solenoid valves are controlled so that the pressure difference between the pilot pressures acting on the ends of the spool valves is proportional to the difference between the actual transmission ratio and the target transmission ratio. When the difference between the actual transmission ratio and the target transmission ratio exceeds the specified value, the target transmission speed is set according to the difference and the output signals to the solenoid valves are controlled so that the pressure difference between the pilot pressures acting on the ends of the spools is proportional to the difference between the actual transmission speed and the target transmission speed.

摘要翻译： 这种环形连续可变传动装置检测滑阀与其中立位置的偏差，并进行反馈控制，以防止传动比从目标传动比或速度变化顺序以外的会聚再次起动。 此外，环形连续可变变速器进行控制，使得随着实际传动比接近目标传动比，传动速度降低，以防止变速控制的过冲。 当实际传动比与目标传动比之间的差小于规定值时，控制到电磁阀的输出信号使得作用于滑阀端部的先导压力之间的压力差与 实际传动比与目标传动比之差。 当实际传动比与目标传动比之间的差值超过规定值时，根据差异来设定目标传动速度，并且控制到电磁阀的输出信号，使得作用于传动比的先导压力之间的压力差 阀芯端部与实际传动速度与目标传动速度之差成正比。

公开(公告)号：US5683324A

公开(公告)日：1997-11-04

申请号：US644188

申请日：1996-05-10

申请人： Eiji Inoue ,  Hirohisa Tanaka

发明人： Eiji Inoue ,  Hirohisa Tanaka

IPC分类号： B60K17/34 ,  B60K17/346 ,  B60K17/348 ,  B60K23/08 ,  F16H15/38 ,  F16H37/02 ,  F16H37/08

CPC分类号： B60K17/348 ,  B60K23/0808 ,  F16H15/38 ,  F16H2015/383 ,  Y10T74/1913 ,  Y10T74/19135

摘要： The toroidal continuous variable transmission for four-wheel drive automobiles distributes a greater torque to the rear wheels than to the front wheels. The torque of the first driven gear is distributed 50% each to the first output shaft and the second output shaft. The torque of the second driven gear is transmitted 100% to the second output shaft. Hence, when the front wheels are connected to the first output shaft and the rear wheels to the second output shaft, the ratio between torques distributed to the front and rear wheels is about 1:3. In the event that only the front wheels should race reducing the transmitted torque, the torque transferred to the second side gear that is not racing also decreases. The rear wheels, however, are supplied with a torque from the second driven gear and therefore can secure at least 50% of the input shaft torque.

摘要翻译： 用于四轮驱动汽车的环形连续可变传动装置比后轮分配比后轮更大的扭矩。 第一从动齿轮的扭矩分别为50％分配给第一输出轴和第二输出轴。 第二从动齿轮的扭矩传递至第二输出轴100％。 因此，当前轮与第一输出轴和后轮连接到第二输出轴时，分配给前轮和后轮的扭矩之比约为1:3。 在只有前轮应该减小传递扭矩的情况下，传递到不竞赛的第二侧档的扭矩也降低。 然而，后轮被提供有来自第二从动齿轮的扭矩，因此可以确保输入轴转矩的至少50％。

公开(公告)号：US09784751B2

公开(公告)日：2017-10-10

申请号：US14113385

申请日：2012-04-25

申请人： Takashi Obara ,  Eiji Inoue

发明人： Takashi Obara ,  Eiji Inoue

IPC分类号： G01N33/68 ,  C12N9/12

CPC分类号： G01N33/6896 ,  C12N9/12 ,  C12Y207/10001 ,  G01N2800/2814 ,  G01N2800/2821

摘要： A method for detecting a neurological disease associated with cognitive impairment, wherein the extracellular domain of EphA4 is measured from a biological sample taken from a subject.

公开(公告)号：US08865426B2

公开(公告)日：2014-10-21

申请号：US13993126

申请日：2011-12-08

申请人： Eiji Inoue

发明人： Eiji Inoue

IPC分类号： C12Q1/37

CPC分类号： C12Q1/37 ,  C12Q1/485 ,  G01N2333/91205 ,  G01N2333/96494 ,  G01N2500/02

摘要： The object of the present invention is to provide a method for screening a substance that affects gelatinase-mediated EphA4 processing. The present invention provides a method for screening a substance that affects gelatinase-mediated EphA4 processing, which comprises the steps of: (a) allowing a first biological composition containing gelatinase or a biologically active fragment thereof to be contacted with a second biological composition containing EphA4 in the presence and absence of a candidate substance; (b) measuring the presence or amount of the EphA4 ectodomain and/or endodomain fragment; and (c) selecting the candidate substance as a substance that affects gelatinase-mediated EphA4 processing if the results of the step (b) measured in the presence of the candidate substance are changed in comparison with the results of the step (b) measured in the absence of the candidate substance.

摘要翻译： 本发明的目的是提供一种筛选影响明胶酶介导的EphA4处理的物质的方法。 本发明提供一种筛选影响明胶酶介导的EphA4处理的物质的方法，其包括以下步骤：（a）使含有明胶酶或其生物活性片段的第一生物组合物与含有EphA4的第二生物组合物接触 在候选物质的存在和不存在的情况下; （b）测量EphA4胞外域和/或endodomain片段的存在或量; 如果在候选物质存在下测量的步骤（b）的结果与步骤（b）中测得的步骤（b）的结果相比改变，则将候选物质选择为影响明胶酶介导的EphA4处理的物质; 没有候选物质。

公开(公告)号：US20140024487A1

公开(公告)日：2014-01-23

申请号：US14005217

申请日：2012-03-09

申请人： Kazutaka Tanaka ,  Yasuyuki Matsuda ,  Takashi Imanishi ,  Eiji Inoue ,  Hiroyasu Yoshioka ,  Tsutomu Hibi

发明人： Kazutaka Tanaka ,  Yasuyuki Matsuda ,  Takashi Imanishi ,  Eiji Inoue ,  Hiroyasu Yoshioka ,  Tsutomu Hibi

IPC分类号： F16H13/08

CPC分类号： F16H13/08 ,  F16H13/06 ,  F16H13/10 ,  F16H13/14 ,  F16H2200/0021 ,  H02K7/116 ,  Y02T10/641

摘要： Construction of a friction roller reducer is achieved wherein displacement of intermediate rollers due to the change in thickness in the axial direction of loading cam apparatuses can be performed smoothly, and excellent transmission efficiency can be obtained. Long guide holes that are long in the radial direction of a sun roller and ring-shaped roller are provided in guide blocks that are fastened to a support frame for supporting the end sections of rotation shafts of intermediate rollers. The outer rings of ball bearings, of which the inner rings are fitted around and fastened to the outside of the end sections of the rotation shafts, engage with the long guide holes so as to be able to displace in the radial direction of the sun roller and the ring-shaped roller.

摘要翻译： 实现摩擦辊减速器的构造，其中可以平稳地执行由于加载凸轮装置的轴向方向上的厚度变化而导致的中间辊的位移，并且可以获得良好的传动效率。 在太阳辊和环形辊的径向方向上长的长导向孔设置在导向块中，导向块紧固到用于支撑中间辊的旋转轴的端部的支撑框架。 内圈安装在旋转轴的端部外侧的球轴承的外圈与长导向孔接合，能够在太阳辊的径向方向上移位 和环形辊。

公开(公告)号：US20110130244A1

公开(公告)日：2011-06-02

申请号：US12953881

申请日：2010-11-24

申请人： Hiroki Nishii ,  Toshihiko Sato ,  Eiji Inoue ,  Toshiro Toyoda ,  Hiroyasu Yoshioka ,  Yuji Shimomura ,  Shin Yamamoto

发明人： Hiroki Nishii ,  Toshihiko Sato ,  Eiji Inoue ,  Toshiro Toyoda ,  Hiroyasu Yoshioka ,  Yuji Shimomura ,  Shin Yamamoto

IPC分类号： F16H15/38

CPC分类号： F16H15/38

摘要： A toroidal continuously variable transmission of the present invention comprises: input side disks (1a, 1b) and output side disks (6) being supported concentric with each other such that the disks can rotate freely; a trunnion (9) that comprises end sections (36) on both ends on which tilt shafts (13) that are concentric with each other are provided, and a support beam section (15) that extends between both end sections (36), the trunnion (9) being capable of pivotally displacing around the tilt shafts (13); a thrust rolling bearing (17); and a power roller (8) that is supported to the inside surface of the trunnion (9) by way of the thrust rolling bearing (17) such that it rotates freely; wherein the support beam section (15) comprises an inside surface having a cylindrical convex surface (14); the thrust rolling bearing (17) comprises an outer race (18a) having an outside surface with a concave section (19a) that fits with the cylindrical convex surface (14) of the support beam section (15), and a plurality of rolling bodies (26) that are located between the power roller (8) and a track of an outer race (18a); and the concave section (19a) of the outer race (18a) has side surface sections (29) on both sides in the width direction, fits with the cylindrical convex surface (14) by the cylindrical convex surface (14) coming in contact with both side surface sections (29).

摘要翻译： 本发明的环形无级变速器包括：彼此同心地支撑的输入侧盘（1a，1b）和输出侧盘（6），使得盘可以自由旋转; 耳轴（9），其包括在两端上的端部部分（36），所述端部彼此同心的倾斜轴（13）设置在所述两端上;以及支撑梁部分（15），其在两个端部部分（36）之间延伸， 耳轴（9）能够围绕倾斜轴（13）枢转移动; 推力滚动轴承（17）; 以及通过所述推力滚动轴承（17）支撑在所述耳轴（9）的内表面以使其自由旋转的动力辊（8） 其中所述支撑梁部分（15）包括具有圆柱形凸起表面（14）的内表面; 推力滚动轴承（17）包括具有外表面的外圈（18a），该外圈具有与支撑梁部（15）的圆柱形凸形表面（14）配合的凹形部分（19a），以及多个滚动体 （26），位于动力辊（8）和外座圈（18a）的轨道之间; 并且所述外圈（18a）的所述凹部（19a）在宽度方向的两侧具有侧面部（29），通过与所述圆筒状的凸面（14）接触而与所述圆筒状的凸面（14）嵌合 两个侧表面部分（29）。

公开(公告)号：US20100190184A1

公开(公告)日：2010-07-29

申请号：US12670987

申请日：2008-08-01

申请人： Eiji Inoue

发明人： Eiji Inoue

IPC分类号： G01N33/53

CPC分类号： C12Q1/37 ,  G01N2333/95 ,  G01N2333/96472 ,  G01N2500/02

摘要： The present invention provides a method of screening for compounds which affect the processing of c-Ret by γ-secretase. The method involves contacting a first biological composition containing γ-secretase or a biologically active fragment thereof with a second biological composition containing c-Ret in the presence and absence of a candidate compound; measuring the cleavage of the c-Ret in the presence and absence of the candidate compound; selecting those candidate compounds which affect the cleavage of the c-Ret by γ-secretase; and identifying the candidate compounds selected in the previous step as compounds which affect the processing of c-Ret by γ-secretase.

摘要翻译： 本发明提供了通过γ-分泌酶筛选影响c-Ret处理的化合物的方法。 所述方法包括在存在和不存在候选化合物的情况下使含有γ-分泌酶或其生物活性片段的第一生物组合物与含有c-Ret的第二生物组合物接触; 在存在和不存在候选化合物的情况下测量c-Ret的切割; 选择通过γ-分泌酶影响c-Ret的切割的候选化合物; 并将在前一步中选择的候选化合物鉴定为影响γ-分泌酶处理c-Ret的化合物。

公开(公告)号：US20080009387A1

公开(公告)日：2008-01-10

申请号：US11757440

申请日：2007-06-04

申请人： Hiroki Nishii ,  Eiji Inoue ,  Jorg Mockel

发明人： Hiroki Nishii ,  Eiji Inoue ,  Jorg Mockel

IPC分类号： F16H15/38

CPC分类号： F16H15/38

摘要： The support beam 34 having the cylindrical convex surface 33 is provided at the intermediate portion of the trunnion 9b. The recess 38 of the partial cylindrical surface formed on the outside of the outer ring 37 on the thrust ball bearing 36 supporting the power rollers 8b and the cylindrical convex surface 33 of the support beam are engaged. The outer ring and the power rollers 8b are supported swingably in the axial direction of the input and output discs in respect to the trunnions 9b.

摘要翻译： 具有圆柱形凸表面33的支撑梁34设置在耳轴9b的中间部分处。 在支撑动力辊8b的推力球轴承36和支撑梁的圆柱形凸起表面33上形成在外圈37的外侧的部分圆柱形表面的凹部38接合。 外圈和动力辊8b相对于耳轴9a在摆动地支承在输入和输出盘的轴向方向上。

公开(公告)号：US07303503B2

公开(公告)日：2007-12-04

申请号：US10631864

申请日：2003-08-01

申请人： Takashi Imanishi ,  Eiji Inoue

发明人： Takashi Imanishi ,  Eiji Inoue

IPC分类号： F16H15/38

CPC分类号： F16H37/086 ,  F16H61/6649 ,  F16H2037/0886

摘要： A toroidal-type continuously variable transmission, has first and second disks respectively including inner surfaces; power rollers interposed for transmitting power; a pressing device for pressing the first disk toward the second disk; a main oil pressure control unit for non-electrically detecting the power for setting, as a target value, an oil pressure necessary for the pressing device when a transmission ratio between the first and second disks is a transmission ratio requiring a maximum pressing force, and increase the target value as the pressing force increases; an oil pressure correcting apparatus for electrically finding a necessary value of the oil pressure, the necessary value corresponding to the optimum value of pressing force generated by the pressing device, and also for introducing an oil pressure of a value into the pressing device, the oil pressure of the value being obtained by subtracting a correction value from the target value.

摘要翻译： 环形无级变速器具有分别包括内表面的第一和第二盘; 动力辊插入用于传递动力; 用于将第一盘朝第二盘按压的按压装置; 主油压控制单元，用于在第一和第二盘之间的传动比是需要最大压力的传动比时，将用于不用电设定的功率作为目标值的压力装置所需的油压，以及 当按压力增加时增加目标值; 油压校正装置，用于找出油压的必要值，与由加压装置产生的按压力的最佳值相对应的必要值，以及用于将压力值引入加压装置的油， 通过从目标值减去校正值而获得的值的压力。

公开(公告)号：US07217216B2

公开(公告)日：2007-05-15

申请号：US11453864

申请日：2006-06-16

申请人： Eiji Inoue

发明人： Eiji Inoue

IPC分类号： F16H15/50

CPC分类号： F16H37/086 ,  F16H2037/0886

摘要： A continuously variable transmission apparatus, has: an input shaft; a toroidal-type continuously variable transmission; a rotation transmission shaft; first, second and third planetary-gear-type transmissions; a first power transmission mechanism; a second power transmission mechanism; a third power transmission mechanism; and, a switching mechanism, wherein the second sun gear and one of the first and third sun gears are rotated together with the rotation transmission shaft to thereby execute the power transmission through the rotation transmission shaft and one of the first and second planetary-gear-type transmissions, and, in a state where the power transmission through the third planetary-gear-type transmission is cut off, in accordance with the control of the transmission ratio of the toroidal-type continuously variable transmission, the output shaft is stopped while the input shaft is rotating.

摘要翻译： 一种无级变速传动装置，具有：输入轴; 环形无级变速器; 旋转传动轴; 第一，第二和第三行星齿轮式变速器; 第一动力传动机构; 第二动力传动机构; 第三动力传动机构; 以及切换机构，其中所述第二太阳齿轮和所述第一和第三太阳齿轮中的一个与所述旋转传动轴一起旋转，从而通过所述旋转传动轴和所述第一和第二行星齿轮传动轴中的一个执行动力传递， 在通过第三行星齿轮式变速器的动力传递被切断的状态下，根据环形无级变速器的变速比的控制，输出轴停止，同时 输入轴正在旋转。