公开(公告)号：US20210072274A1

公开(公告)日：2021-03-11

申请号：US16772390

申请日：2018-02-12

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander N. GOVYADINOV ,  Pavel KORNILOVICH ,  Diane R. HAMMERSTAD

IPC: G01P5/20 ,  B01L3/00 ,  G01F1/708 ,  G05D7/06

Abstract: A microfluidic flow sensor may include a substrate having a microfluidic channel, an inert particle source to supply a fluid carrying an inert particle to the microfluidic channel and a sensor element along the microfluidic channel and spaced from the inert particle source. The sensor element outputs a signal based upon a sensed passage of the inert particle with respect to the sensor element. Portions of the microfluidic channel proximate the sensor element have a first size and wherein the inert particle provided by the inert particle source is to have a second size greater than one half the first size.

公开(公告)号：US20200332342A1

公开(公告)日：2020-10-22

申请号：US16643054

申请日：2017-10-20

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Adam HIGGINS ,  Pavel KORNILOVICH ,  Alexander N. GOVYADINOV ,  Michael J. DAY

IPC: C12Q1/686 ,  C12Q1/6806 ,  B01L7/00 ,  B01L3/00

Abstract: A nucleic acid amplifier may include a sample preparation zone, a fluid ejector, an amplification zone and a capillary break between the amplification zone and the fluid ejector.

公开(公告)号：US20200306751A1

公开(公告)日：2020-10-01

申请号：US16642978

申请日：2017-10-20

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Pavel KORNILOVICH ,  Alexander N. GOVYADINOV

IPC: B01L3/00 ,  F16K31/12

Abstract: A microfluidic device may include a first fluid chamber, a second fluid chamber, a first microfluidic passage extending between the first fluid chamber and the second fluid chamber, a second microfluidic passage extending from the second fluid chamber, a first fluid actuator adjacent the first microfluidic passage and proximate the first fluid chamber to inertially pump fluid away from the first fluid chamber and a second fluid actuator adjacent the first microfluidic passage and proximate the second fluid chamber to menially pump fluid towards the first fluid chamber.

公开(公告)号：US20200179924A1

公开(公告)日：2020-06-11

申请号：US16618200

申请日：2017-07-19

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： David P. MARKEL ,  Erik D TORNIAINEN ,  Alexander GOVYADINOV ,  Pavel KORNILOVICH

IPC: B01L3/00

Abstract: One example includes a device that may include a heating element and a molecular binding site. The heating element may heat a fluid volume, interfaced with the heating element, in response to a voltage being applied to the heating element, the heat transforming the fluid volume from a liquid state into a vaporized state to generate fluid motion within the fluid volume. The molecular binding site may be disposed proximate to the heating element, in which a portion of the fluid volume expands when the fluid volume transforms from the liquid state into the vaporized state, the vaporized state of the fluid volume generating the fluid motion within a target fluid that is disposed within the molecular binding site.