公开(公告)号：US20210170408A1

公开(公告)日：2021-06-10

申请号：US17047930

申请日：2018-06-11

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Pavel KORNILOVICH ,  Daniel C. CURTHOYS ,  Alexander N. GOVYADINOV

IPC: B01L3/00 ,  F16K99/00

Abstract: A microfluidic valve may include a first portion of a liquid conduit to contain a fluid, a second portion of the liquid conduit to contain a liquid and a constriction between the first portion and the second portion and across which a capillary meniscus is to form between the fluid and liquid, the constriction comprising an edge along a ceiling of the constriction.

公开(公告)号：US20210162413A1

公开(公告)日：2021-06-03

申请号：US17047941

申请日：2018-06-18

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander N. GOVYADINOV ,  David P. MARKEL ,  Erik D. TORNIAINEN ,  Pavel KORNILOVICH

IPC: B01L3/00 ,  G01N33/543

Abstract: A microfluidic immunoassay platform may include a substrate, a microfluidic channel in the substrate, a first set of functionalized structures along the channel, a second set of functionalized structures along the channel and an electrically driven fluid actuator contained on the substrate to move fluid containing at least one analyte along the channel through the first set of functionalized structures and through the second set of functionalized structures.

公开(公告)号：US20210072274A1

公开(公告)日：2021-03-11

申请号：US16772390

申请日：2018-02-12

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander N. GOVYADINOV ,  Pavel KORNILOVICH ,  Diane R. HAMMERSTAD

IPC: G01P5/20 ,  B01L3/00 ,  G01F1/708 ,  G05D7/06

Abstract: A microfluidic flow sensor may include a substrate having a microfluidic channel, an inert particle source to supply a fluid carrying an inert particle to the microfluidic channel and a sensor element along the microfluidic channel and spaced from the inert particle source. The sensor element outputs a signal based upon a sensed passage of the inert particle with respect to the sensor element. Portions of the microfluidic channel proximate the sensor element have a first size and wherein the inert particle provided by the inert particle source is to have a second size greater than one half the first size.

公开(公告)号：US20200332342A1

公开(公告)日：2020-10-22

申请号：US16643054

申请日：2017-10-20

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Adam HIGGINS ,  Pavel KORNILOVICH ,  Alexander N. GOVYADINOV ,  Michael J. DAY

IPC: C12Q1/686 ,  C12Q1/6806 ,  B01L7/00 ,  B01L3/00

Abstract: A nucleic acid amplifier may include a sample preparation zone, a fluid ejector, an amplification zone and a capillary break between the amplification zone and the fluid ejector.

公开(公告)号：US20200306751A1

公开(公告)日：2020-10-01

申请号：US16642978

申请日：2017-10-20

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Pavel KORNILOVICH ,  Alexander N. GOVYADINOV

IPC: B01L3/00 ,  F16K31/12

Abstract: A microfluidic device may include a first fluid chamber, a second fluid chamber, a first microfluidic passage extending between the first fluid chamber and the second fluid chamber, a second microfluidic passage extending from the second fluid chamber, a first fluid actuator adjacent the first microfluidic passage and proximate the first fluid chamber to inertially pump fluid away from the first fluid chamber and a second fluid actuator adjacent the first microfluidic passage and proximate the second fluid chamber to menially pump fluid towards the first fluid chamber.

公开(公告)号：US20210069708A1

公开(公告)日：2021-03-11

申请号：US16772350

申请日：2018-02-12

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander N. GOVYADINOV ,  Pavel KORNILOVICH ,  Diane R. HAMMERSTAD

IPC: B01L3/00 ,  G01F1/708 ,  B01F3/04

Abstract: A microfluidic flow sensor may include a substrate having a microfluidic channel, a bubble generator to introduce a bubble into fluid that is directed through the microfluidic channel and a sensor element along the microfluidic channel and spaced from the bubble generator. The sensor element outputs a signal based upon a sensed passage of the bubble with respect to the sensor element. Portions of the microfluidic channel proximate the sensor element have a first size and wherein the bubble generated by the bubble generator is to have a second size greater than one half the first size.

公开(公告)号：US20190299169A1

公开(公告)日：2019-10-03

申请号：US16316896

申请日：2016-10-21

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Erik D. TORNIAINEN ,  Alexander N. GOVYADINOV ,  Pavel KORNILOVICH ,  David P. MARKEL ,  Richard W. SEAVER

IPC: B01F3/08 ,  B01F13/00 ,  B01F15/02 ,  B01F5/02 ,  B01F5/04

Abstract: An immiscible droplet generation system may include a chip, a microfluidic channel integrated into the chip, an input to the microfluidic channel through which the microfluidic channel is to be filled with a first fluid that is to be moved through the microfluidic channel and a droplet generator. The droplet generator is integrated into the chip to generate a droplet of a second fluid, immiscible within the first fluid, and to inject the droplet into the first fluid in the microfluidic channel.

公开(公告)号：US20190291102A1

公开(公告)日：2019-09-26

申请号：US16317429

申请日：2016-09-23

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Pavel Kornilovich ,  Alexander N. GOVYADINOV

IPC: B01L3/00

Abstract: A microfluidic device may include at least four interconnected microfluidic channels and a set of fluid actuators. The set of fluid actuators may include a fluid actuator asymmetrically located within at least two of the at least four interconnected microfluidic channels. Each of the at least four interconnected microfluidic channels may be activated to a fluid inputting state, a fluid outputting state and a fluid blocking state in response to selective actuation of different combinations of fluid actuators of the set.