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公开(公告)号:US20200179924A1
公开(公告)日:2020-06-11
申请号:US16618200
申请日:2017-07-19
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: David P. MARKEL , Erik D TORNIAINEN , Alexander GOVYADINOV , Pavel KORNILOVICH
IPC: B01L3/00
Abstract: One example includes a device that may include a heating element and a molecular binding site. The heating element may heat a fluid volume, interfaced with the heating element, in response to a voltage being applied to the heating element, the heat transforming the fluid volume from a liquid state into a vaporized state to generate fluid motion within the fluid volume. The molecular binding site may be disposed proximate to the heating element, in which a portion of the fluid volume expands when the fluid volume transforms from the liquid state into the vaporized state, the vaporized state of the fluid volume generating the fluid motion within a target fluid that is disposed within the molecular binding site.
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公开(公告)号:US20200030760A1
公开(公告)日:2020-01-30
申请号:US16300975
申请日:2016-07-06
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander GOVYADINOV , Pavel KORNILOVICH , Erik D. TORNIAINEN , David P. MARKEL
Abstract: One example provides a microfluidic mixing device that includes a main fluidic channel to provide main fluidic channel flow and a number of I-shaped secondary channels extending outwardly from a portion of the main fluidic channel. A number of inertial pumps are located within the I-shaped secondary channels to create serpentine flows in the direction of the main fluidic channel flow or create vorticity-inducing counterflow in the main fluidic channel.
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公开(公告)号:US20190151846A1
公开(公告)日:2019-05-23
申请号:US16099246
申请日:2016-07-12
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel KORNILOVICH , Alexander GOVYADINOV , David P. MARKEL , Erik D. TORNIAINEN
IPC: B01L3/00
Abstract: A microfluidic bead-packing method includes activating a first micropump to transfer active microbeads through an inlet microchannel from a bead suspension reservoir to an adsorbing channel; packing the microbeads in the adsorbing channel; and activating a second micropump to reverse flow through at least a portion of the inlet microchannel and to transfer a sample fluid through the inlet microchannel from a sample reservoir to the adsorbing channel such that the sample fluid interacts with the packed microbeads.
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公开(公告)号:US20210162413A1
公开(公告)日:2021-06-03
申请号:US17047941
申请日:2018-06-18
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander N. GOVYADINOV , David P. MARKEL , Erik D. TORNIAINEN , Pavel KORNILOVICH
IPC: B01L3/00 , G01N33/543
Abstract: A microfluidic immunoassay platform may include a substrate, a microfluidic channel in the substrate, a first set of functionalized structures along the channel, a second set of functionalized structures along the channel and an electrically driven fluid actuator contained on the substrate to move fluid containing at least one analyte along the channel through the first set of functionalized structures and through the second set of functionalized structures.
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公开(公告)号:US20190001335A1
公开(公告)日:2019-01-03
申请号:US15748975
申请日:2016-01-08
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Erik D. TORNIAINEN , Alexander GOVYADINOV , Pavel KORNILOVICH , David P. MARKEL
Abstract: Examples include polymerase chain reaction (PCR) devices. Example PCR devices comprise a fluid input, ejection nozzles, and a set of microfluidic channels that fluidly connect the fluid input and the ejection nozzles. Each microfluidic channel comprises a reaction chamber, and examples further comprise at least one heating element, where the at least one heating element is positioned in the reaction chamber of each microfluidic channel. The at least one heating element is to heat fluid in the reaction chamber of each fluid channel. The device may eject fluid via the ejection nozzles.
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公开(公告)号:US20190299169A1
公开(公告)日:2019-10-03
申请号:US16316896
申请日:2016-10-21
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Erik D. TORNIAINEN , Alexander N. GOVYADINOV , Pavel KORNILOVICH , David P. MARKEL , Richard W. SEAVER
Abstract: An immiscible droplet generation system may include a chip, a microfluidic channel integrated into the chip, an input to the microfluidic channel through which the microfluidic channel is to be filled with a first fluid that is to be moved through the microfluidic channel and a droplet generator. The droplet generator is integrated into the chip to generate a droplet of a second fluid, immiscible within the first fluid, and to inject the droplet into the first fluid in the microfluidic channel.
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公开(公告)号:US20190176111A1
公开(公告)日:2019-06-13
申请号:US16300182
申请日:2016-07-08
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: David P. MARKEL , Erik D. TORNIAINEN , Alexander GOVYADINOV , Pavel KORNILOVICH
Abstract: Examples include microfluidic devices. Example microfluidic devices comprise a first microfluidic channel, a second microfluidic channel, and microfluidic output channel fluidly coupled to the first microfluidic channel and the second microfluidic channel via a fluid junction. The example device comprises a fluid actuator disposed in the microfluidic output channel to actuate to thereby pump a first fluid and a second fluid into the microfluidic output channel.
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公开(公告)号:US20190143327A1
公开(公告)日:2019-05-16
申请号:US16300115
申请日:2016-07-15
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel KORNILOVICH , Alexander GOVYADINOV , David P. MARKEL , Erik D. TORNIAINEN
IPC: B01L3/00
Abstract: A microfluidic filtering system may include a first microfluidic channel, a first pump to move fluid along the first microfluidic channel in a first direction, a second microfluidic channel, a second pump to move fluid along the second microfluidic channel in a second direction opposite to the first direction and a filter channel extending between and interconnecting the first microfluidic channel and the second microfluidic channel.
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