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公开(公告)号:US20230330673A1
公开(公告)日:2023-10-19
申请号:US17721650
申请日:2022-04-15
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Oumnia El Fajri , Richard W. SEAVER , Erik D. TORNIAINEN , Anand Samuel JEBAKUMAR , Pavel KORNILOVICH , Alexander GOVYADINOV , Carson DENISON
IPC: B01L3/00
CPC classification number: B01L3/502753 , B01L3/50273 , B01L2200/12 , B01L2200/16 , B01L2400/0406 , B01L2300/12
Abstract: An example microfluidic structure can include a first microfluidic channel segment in a first elevation plane, a second microfluidic channel segment in a second elevation plane, and a transverse microfluidic channel segment connecting the first microfluidic channel segment to the second microfluidic channel segment. An angled exterior wall segment can be at the transverse microfluidic channel segment. The angled exterior wall segment can be angled in the first or second elevation plane at an acute angle with respect to a direction of fluid flow through the first or second microfluidic channel segment. A fluid cross-sectional area can increase in the fluid flow direction along the angled exterior wall segment.
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公开(公告)号:US20210245151A1
公开(公告)日:2021-08-12
申请号:US17049761
申请日:2018-08-10
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Michael W. CUMBIE , Chien-Hua CHEN , Pavel KORNILOVICH
IPC: B01L3/00
Abstract: A dual direction dispenser may include a fluid channel, a first ejection orifice extending in a first direction from the fluid channel, a first fluid actuator to displace fluid through the first ejection orifice, a second ejection orifice extending in a second direction, different than the first direction, from the fluid channel and a second fluid actuator to displace fluid through the second ejection orifice.
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公开(公告)号:US20210162413A1
公开(公告)日:2021-06-03
申请号:US17047941
申请日:2018-06-18
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander N. GOVYADINOV , David P. MARKEL , Erik D. TORNIAINEN , Pavel KORNILOVICH
IPC: B01L3/00 , G01N33/543
Abstract: A microfluidic immunoassay platform may include a substrate, a microfluidic channel in the substrate, a first set of functionalized structures along the channel, a second set of functionalized structures along the channel and an electrically driven fluid actuator contained on the substrate to move fluid containing at least one analyte along the channel through the first set of functionalized structures and through the second set of functionalized structures.
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公开(公告)号:US20190001335A1
公开(公告)日:2019-01-03
申请号:US15748975
申请日:2016-01-08
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Erik D. TORNIAINEN , Alexander GOVYADINOV , Pavel KORNILOVICH , David P. MARKEL
Abstract: Examples include polymerase chain reaction (PCR) devices. Example PCR devices comprise a fluid input, ejection nozzles, and a set of microfluidic channels that fluidly connect the fluid input and the ejection nozzles. Each microfluidic channel comprises a reaction chamber, and examples further comprise at least one heating element, where the at least one heating element is positioned in the reaction chamber of each microfluidic channel. The at least one heating element is to heat fluid in the reaction chamber of each fluid channel. The device may eject fluid via the ejection nozzles.
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公开(公告)号:US20230381723A1
公开(公告)日:2023-11-30
申请号:US17826943
申请日:2022-05-27
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson Denison , Richard W. SEAVER , Erik D. TORNIAINEN , Pavel KORNILOVICH , Alexander GOVYADINOV , Anand Samuel JEBAKUMAR , Oumnia EL FAJRI
IPC: B01F33/3012 , B01F35/71
CPC classification number: B01F33/3012 , B01F35/7172 , B01F2101/2204
Abstract: An example microfluidic mixer can include an inlet microfluidic channel portion and a fluid splitting channel portion including an overpass microfluidic channel to receive fluid from a first side of the inlet microfluidic channel portion and an underpass microfluidic channel to receive fluid from a second side of the inlet microfluidic channel portion, where the underpass microfluidic channel extends under the overpass microfluidic channel such that the channels overlap at their respective downstream ends. A fluid recombining channel portion is downstream of the fluid splitting portion and includes an angled recombining surface having an acute angle with respect to a direction of fluid flow, where the angled recombining surface is between the downstream ends of the overpass and underpass microfluidic channels. An outlet microfluidic channel portion is fluidly connected downstream from the fluid recombining channel portion.
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公开(公告)号:US20210331152A1
公开(公告)日:2021-10-28
申请号:US16608289
申请日:2018-07-17
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel KORNILOVICH , John LAHMANN , Alexander GOVYADINOV , Diane R HAMMERSTAD
Abstract: An example device includes a droplet ejector including a nozzle to eject droplets of a fluid and a target medium to receive the droplets of the fluid. The target medium is separated from the droplet ejector by a gap to be traversed by the droplets. The example device further includes a frame affixing the target medium to the droplet ejector. The target medium is immovably held with respect to the droplet ejector.
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公开(公告)号:US20210206081A1
公开(公告)日:2021-07-08
申请号:US16074551
申请日:2017-03-14
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Michael G. MONROE , Pavel KORNILOVICH , Andrew QUEISSER , Glenn HADDICK
IPC: B29C64/307 , B29C64/393 , B29C64/264
Abstract: A material development tool includes a first plate and a second plate. The first plate has an indentation of a predetermined depth. The second plate having an opening for receiving build material when placed on the first plate and is removable from the first plate. A recoater is used to move and spread the build material within the indentation of the first plate.
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公开(公告)号:US20210138458A1
公开(公告)日:2021-05-13
申请号:US17045873
申请日:2018-11-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: John LAHMANN , Pavel KORNILOVICH , Silam J CHOY
IPC: B01L3/00
Abstract: An example method includes providing fluid to a chamber. The chamber feeds a first channel terminating at a first droplet ejector and a second channel terminating at a second droplet ejector. The method further includes sequencing ejection of droplets at the first droplet ejector and the second droplet ejector to induce negative pressure to provide a sequenced output flow of the fluid through the first channel to a first target microfluidic network and through the second channel to a second target microfluidic network, and controlling the first and second target microfluidic networks to perform an analytical process with the fluid.
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公开(公告)号:US20210023555A1
公开(公告)日:2021-01-28
申请号:US17045739
申请日:2018-11-21
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: John LAHMANN , Silam J CHOY , Pavel KORNILOVICH
IPC: B01L3/00
Abstract: An example device includes a chamber including a fluid inlet, a fluid outlet, and a negative-pressure port. The negative-pressure port is positioned relative to the fluid inlet to draw a droplet of a fluid from the fluid inlet into the chamber when the fluid is applied to the fluid inlet and negative pressure is applied to the negative-pressure port. The fluid outlet is positioned relative to the fluid inlet to collect the droplet. The example device further includes a downstream microfluidic channel connected to the fluid outlet of the chamber. The downstream microfluidic channel communicates capillary action to the fluid outlet of the chamber. The capillary action resists flow of the fluid from the fluid outlet into the chamber induced by the negative pressure applied to the negative-pressure port.
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公开(公告)号:US20240082839A1
公开(公告)日:2024-03-14
申请号:US18272792
申请日:2021-01-22
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson DENISON , Erik D. TORNIAINEN , Richard W. SEAVER , Pavel KORNILOVICH , Alexander GOVYADINOV , Anand Samuel JEBAKUMAR
IPC: B01L3/00
CPC classification number: B01L3/502746 , B01L2200/0642 , B01L2200/0684 , B01L2300/0848 , B01L2300/0874 , B01L2400/086
Abstract: A microfluidic device includes a chamber having sidewalls, a floor, a ceiling, and an inlet. The microfluidic device includes pillars extending from the floor to the ceiling of the chamber. Each pillar has an orientation relative to the inlet defined by a leading surface and a trailing corner opposite the leading corner. The trailing corner has an angle less than a threshold angle that is based on a fluidic contact angle. The orientations of the pillars relative to the inlet promote fluid flow from the inlet throughout the chamber without trapping gas at the sidewalls of the chamber.
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