公开(公告)号：US20160356715A1

公开(公告)日：2016-12-08

申请号：US15175489

申请日：2014-12-09

Applicant: Illumina, Inc.

Inventor： Cheng Frank Zhong ,  Hod Finkelstein ,  Boyan Boyanov ,  Dietrich Dehlinger ,  Darren Segale

IPC: G01N21/64 ,  G01N21/05

CPC classification number: G01N21/645 ,  B01L3/502707 ,  B01L3/502715 ,  G01N21/05 ,  G01N21/6428 ,  G01N21/6454 ,  G01N33/54373 ,  G01N2021/6441 ,  G01N2021/6482 ,  G01N2201/061 ,  G01N2201/0642

Abstract: Biosensor including a device base having a sensor array of light sensors and a guide array of light guides. The light guides have input regions that are configured to receive excitation light and light emissions generated by biological or chemical substances. The light guides extend into the device base toward corresponding light sensors and have a filter material. The device base includes device circuitry electrically coupled to the light sensors and configured to transmit data signals. The biosensor also includes a shield layer having apertures that are positioned relative to the input regions of corresponding light guides such that the light emissions propagate through the apertures into the corresponding input regions. The shield layer extends between adjacent apertures and is configured to block the excitation light and the light emissions incident on the shield layer between the adjacent apertures.

Abstract translation: 生物传感器包括具有光传感器的传感器阵列的装置基座和光导的引导阵列。 光导具有被配置为接收由生物或化学物质产生的激发光和发光的输入区域。 光导件延伸到装置底座中朝向相应的光传感器并具有过滤材料。 器件基底包括电耦合到光传感器并被配置为传输数据信号的器件电路。 生物传感器还包括具有相对于相应光导的输入区域定位的孔的屏蔽层，使得光发射通过孔径传播到相应的输入区域。 屏蔽层在相邻的孔之间延伸并且被配置为阻挡入射在相邻孔之间的屏蔽层上的激发光和发光。