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公开(公告)号：US06414049B1
公开(公告)日：2002-07-02
申请号：US09532234
申请日：2000-03-22
申请人： Azaam Alli , Joe M. Wood , Ivan M. Nunez , Robert N. Love , James D. Ford , Douglas G. Vanderlaan
发明人： Azaam Alli , Joe M. Wood , Ivan M. Nunez , Robert N. Love , James D. Ford , Douglas G. Vanderlaan
IPC分类号： C08F248
CPC分类号： G02B1/043 , C08F2/46 , C08F230/08 , C08F290/148 , Y10S524/916 , C08L51/085 , C08L43/04
摘要： Acylphosphine initiators used in making ophthalmic lenses are stabilized by the addition of an acid to the monomer mix used to make the lenses.
摘要翻译： 用于制造眼镜片的酰基膦引发剂通过向用于制造透镜的单体混合物中加入酸而稳定。
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32.发明授权
公开(公告)号：US5684058A
公开(公告)日：1997-11-04
申请号：US410025
申请日：1995-03-24
IPC分类号： C08J5/00 , B29D11/02 , C08F2/00 , C08F2/44 , C08F2/48 , C08L71/02 , G02B1/04 , C08F24/00 , G02C7/04
CPC分类号： G02B1/043 , C08F2/00 , Y10S524/916
摘要： Shaped hydrogel articles such as soft contact lenses are prepared by the steps of: (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, and one or more cross-linking monomers; and (b) an inert, displaceable diluent selected from the group consisting of: (i) ethoxylated alkyl glucoside; (ii) ethoxylated bisphenol A; (iii) polyethylene glycol; (iv) mixture of propoxylated and ethoxylated alkyl glucoside; (v) single phase mixture of ethoxylated or propoxylated alkyl glucoside and C.sub.2-12 dihydric alcohol; (vi) adduct of .epsilon.-caprolactone and C.sub.2-6 alkanediols and triols;(vii) ethoxylated C.sub.3-6 alkanetriol; and (viii) mixtures of one or more of (i) through (vii), under conditions to polymerize said monomer mixture to produce a shaped gel of a copolymer of said monomers and said diluent; and (2) thereafter replacing said diluent with water.
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33.发明授权
公开(公告)号：US5498379A
公开(公告)日：1996-03-12
申请号：US455357
申请日：1995-05-31
IPC分类号： C08J5/00 , B29D11/02 , C08F2/00 , C08F2/44 , C08F2/48 , C08L71/02 , G02B1/04 , B29D11/00 , C08J7/02 , C08K5/12 , C08L101/14
CPC分类号： G02B1/043 , C08F2/00 , Y10S524/916
摘要： Shaped hydrogel articles such as soft contact lenses are prepared by the steps of:(1) molding or casting a polymerization mixture comprising:(a) a monomer mixture comprising a major proportion of one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, and one or more cross-linking monomers; and(b) an inert, displaceable diluent selected from the group consisting of:(i) ethoxylated alkyl glucoside;(ii) ethoxylated bisphenol A;(iii) polyethylene glycol;(iv) mixture of propoxylated and ethoxylated alkyl glucoside;(v) single phase mixture of ethoxylated or propoxylated alkyl glucoside and C.sub.2-12 dihydric alcohol;(vi) adduct of .epsilon.-caprolactone and C.sub.2-6 alkanediols and triols;(vii) ethoxylated C.sub.3-6 alkanetriol; and(viii) mixtures of one or more of (i) through (vii),under conditions to polymerize said monomer mixture to produce a shaped gel of a copolymer of said monomers and said diluent; and(2) thereafter replacing said diluent with water.
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34.发明授权Method of testing inert, displaceable diluents used in forming shaped hydrogel articles 失效用于形成成形水凝胶制品的惰性可置换稀释剂的测试方法
公开(公告)号：US5736409A
公开(公告)日：1998-04-07
申请号：US645999
申请日：1996-05-14
IPC分类号： C08J5/00 , B29D11/02 , C08F2/00 , C08F2/44 , C08F2/48 , C08L71/02 , G02B1/04 , G01N25/20 , B29D11/00
CPC分类号： G02B1/043 , C08F2/00 , Y10S524/916
摘要： Method of testing inert displaceable diluents used in forming shaped hydrogel articles such as soft contact lenses prepared by the steps of: (1) molding or casting a polymerization mixture including: (a) a monomer mixture having a major proportion of one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, and one or more cross-linking monomers; and (b) an inert, displaceable diluent chosen from: (i) ethoxylated alkyl glucoside; (ii) ethoxylated bisphenol A; (iii) polyethylene glycol; (iv) mixture of propoxylated and ethoxylated alkyl glucoside; (v) single phase mixture of ethoxylated or propoxylated alkyl gtucoside and C.sub.2-12 dihydric alcohol; (vi) adduct of .epsilon.-caprolactone and C.sub.2-6 alkanediols and triols;(vii) ethoxylated C.sub.3-6 alkanetriol; and (viii) mixtures of one or more of (i) through (vii), under conditions to polymerize the monomer mixture to produce a shaped gel of a copolymer of the monomers and the diluent; and (2) thereafter replacing the diluent with water.
摘要翻译： 测试用于形成成形水凝胶制品（例如由以下步骤制备的软性隐形眼镜）的惰性可置换稀释剂的方法：（1）模制或浇铸聚合混合物，其包括：（a）主要比例的一种或多种亲水单体的单体混合物 如甲基丙烯酸2-羟乙酯和一种或多种交联单体; 和（b）惰性的可置换的稀释剂，其选自：（i）乙氧基化烷基葡糖苷; （ii）乙氧基化双酚A; （iii）聚乙二醇; （iv）丙氧基化和乙氧基化烷基葡糖苷的混合物; （v）乙氧基化或丙氧基化烷基葡糖苷和C2-12二元醇的单相混合物; （vi）ε-己内酯和C 2-6烷二醇和三醇的加合物; （vii）乙氧基化C3-6烷醇三醇; 和（viii）（i）至（vii）中的一种或多种的混合物，在使单体混合物聚合以产生单体和稀释剂的共聚物的成形凝胶的条件下; 和（2）此后用水代替稀释剂。
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公开(公告)号：US5723131A
公开(公告)日：1998-03-03
申请号：US580233
申请日：1995-12-28
IPC分类号： G02C7/04 , A61K9/00 , A61K31/16 , A61K47/40 , B29D11/02 , B29K33/04 , B29L11/00 , G02B1/04 , G02C13/00 , A61F13/00
CPC分类号： G02B1/043 , A61K9/0051
摘要： A contact lens made of a polymeric hydrogel material having absorbed therein as a leachable additive of desferrioxamine, and a method for making the composition by soaking the polymeric material in a solution of the additive.
摘要翻译： 由其中作为脱铁胺的可浸出添加剂吸收的聚合物水凝胶材料制成的隐形眼镜，以及通过将聚合物材料浸泡在添加剂溶液中来制备该组合物的方法。
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公开(公告)号：US5648402A
公开(公告)日：1997-07-15
申请号：US457832
申请日：1995-06-01
IPC分类号： G02C7/04 , A61F2/16 , A61F9/00 , A61L27/00 , C08F299/00 , C08G18/50 , C08G77/42 , G02B1/04 , C08G18/61 , C07H15/08 , C08G18/64
摘要： The present invention provides soft contact lenses adopted for placement over the cornea or in the eye which have a high oxygen permeability, a low water content and excellent mechanical properties. Moreover, the lenses of the instant invention have excellent protein and lipid deposition resistance relative to conventional contact lenses. Such lenses having the properties mentioned above comprises a prepolymer which contains an alkoxylate glucoside that is derivatized with at least one polysiloxane compound. The prepolymer is then placed in a suitable mold and polymerized by exposure to ultraviolet light.
摘要翻译： 本发明提供了用于放置在角膜或眼睛中的具有高透氧性，低含水量和优异的机械性能的软性隐形眼镜。 此外，本发明的镜片相对于常规隐形眼镜具有优异的蛋白质和脂质沉积阻力。 具有上述性质的这种透镜包含预聚物，其包含用至少一种聚硅氧烷化合物衍生化的烷氧基化物葡糖苷。 然后将预聚物置于合适的模具中，并通过暴露于紫外线进行聚合。
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37.发明授权
公开(公告)号：US5490960A
公开(公告)日：1996-02-13
申请号：US456133
申请日：1995-05-31
IPC分类号： C08J5/00 , B29D11/02 , C08F2/00 , C08F2/44 , C08F2/48 , C08L71/02 , G02B1/04 , B29D11/00 , C08L33/14
CPC分类号： G02B1/043 , C08F2/00 , Y10S524/916
摘要： Shaped hydrogel articles such as soft contact lenses are prepared by the steps of:(1) molding or casting a polymerization mixture comprising:(a) a monomer mixture comprising a major proportion of one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, and one or more cross-linking monomers; and(b) an inert, displaceable diluent selected from the group consisting of:(i) ethoxylated alkyl glucoside;(ii) ethoxylated bisphenol A;(iii) polyethylene glycol;(iv) mixture of propoxylated and ethoxylated alkyl glucoside;(v) single phase mixture of ethoxylated or propoxylated alkyl glucoside and C.sub.2-12 dihydric alcohol;(vi) adduct of .epsilon.-caprolactone and C.sub.2-6 alkanediols and triols;(vii) ethoxylated C.sub.3-6 alkanetriol; and(viii) mixtures of one or more of (i) through (vii),under conditions to polymerize said monomer mixture to produce a shaped gel of a copolymer of said monomers and said diluent; and(2) thereafter replacing said diluent with water.
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公开(公告)号：US08138288B2
公开(公告)日：2012-03-20
申请号：US13039912
申请日：2011-03-03
IPC分类号： C08F30/08 , C08F290/00
CPC分类号： C08G77/388 , G02B1/043 , C08L83/08
摘要： This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing the cationic siloxane prepolymer.
摘要翻译： 本申请涉及一种改进的合成阳离子硅氧烷预聚物的方法以及具有改进的与单官能硅氧烷基甲基丙烯酸酯单体的相容性和含有阳离子硅氧烷预聚物的医疗装置的特异性阳离子硅氧烷预聚物。
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公开(公告)号：US07951897B2
公开(公告)日：2011-05-31
申请号：US12018910
申请日：2008-01-24
CPC分类号： C08G77/388 , G02B1/043 , C08L83/08
摘要： This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing the cationic siloxane prepolymer.
摘要翻译： 本申请涉及一种改进的合成阳离子硅氧烷预聚物的方法以及具有改进的与单官能硅氧烷基甲基丙烯酸酯单体的相容性和含有阳离子硅氧烷预聚物的医疗装置的特异性阳离子硅氧烷预聚物。
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公开(公告)号：US07887882B2
公开(公告)日：2011-02-15
申请号：US11054673
申请日：2005-02-09
CPC分类号： G02B1/041
摘要： The invention provides UV absorber solutions that do not require use of a solvent to prevent formation of insoluble reaction products. The invention is useful in the manufacture of ocular devices including spectacle, contact and intraocular lenses, but may find its greatest utility in the manufacture of spectacle lenses.
摘要翻译： 本发明提供了不需要使用溶剂以防止形成不溶性反应产物的紫外线吸收剂溶液。 本发明可用于制造包括眼镜，接触和眼内透镜在内的眼部装置，但是可以在制造眼镜镜片中发挥其最大的用途。
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