公开(公告)号：US20120201107A1

公开(公告)日：2012-08-09

申请号：US13020253

申请日：2011-02-03

申请人： Chubing Peng ,  Yongjun Zhao

发明人： Chubing Peng ,  Yongjun Zhao

IPC分类号： G11B7/135

CPC分类号： G11B5/6088

摘要： An apparatus includes a light source for producing a beam of light, a coupler for coupling the light into a slider waveguide, a beam expander for expanding the beam of light from the waveguide to produce an expanded beam, a collimator for collimating the expanded beam, and a focusing device for concentrating the collimated beam to a focal point. A method of delivering light to a focal point is also described.

摘要翻译： 一种装置包括用于产生光束的光源，用于将光耦合到滑块波导中的耦合器，用于扩展来自波导的光束以产生扩展光束的光束扩展器，用于准直扩展光束的准直器， 以及用于将准​​直光束聚焦到焦点的聚焦装置。 还描述了将光传递到焦点的方法。

公开(公告)号：US20090009906A1

公开(公告)日：2009-01-08

申请号：US11772353

申请日：2007-07-02

申请人： Wayne Allen Bonin ,  Earl Chrzaszcz Johns ,  Yongjun Zhao

发明人： Wayne Allen Bonin ,  Earl Chrzaszcz Johns ,  Yongjun Zhao

IPC分类号： G11B5/012

CPC分类号： G11B9/02

摘要： An apparatus includes a storage medium, a transducer positioned adjacent to the storage medium and along an axis, and first and second support members connected to the transducer at positions that are spaced apart in the direction of the axis.

摘要翻译： 一种装置包括存储介质，与存储介质相邻并且沿着轴定位的换能器，以及在沿轴线方向间隔开的位置处连接到换能器的第一和第二支撑构件。

公开(公告)号：US07223891B2

公开(公告)日：2007-05-29

申请号：US10539163

申请日：2003-12-19

申请人： Frank Brady ,  Sajinder Kaur Luthra ,  Yongjun Zhao

发明人： Frank Brady ,  Sajinder Kaur Luthra ,  Yongjun Zhao

IPC分类号： C07C17/00 ,  C07C17/42

CPC分类号： C07C17/204 ,  C07B2200/05 ,  C07C17/093

摘要： The invention relates to a process for the production of an [18F]fluorohaloalkane which comprises treatment of a solid support-bound precursor of formula (I): SOLID SUPPORT-LINKER-SO2—O—(CH2)nX (I) wherein n is an integer of from (1) to (7) and X is chloro, bromo or iodo; with 18F− to produce the [18F]fluorohaloalkane of formula (II) 18F—(CH2)n—X (II) wherein n and X are as defined for the compound of formula (I), optionally followed by (i) removal of excess 18F−, for example by ion-exchange chromatography; and/or (ii) removal of organic solvent.

摘要翻译： 本发明涉及一种制备[18 F]氟卤代烷烃的方法，该方法包括处理式（I）的固体载体结合的前体：固体支持物 - 其中n为（1）至（7）的整数，X为氯，溴或氯，或（C 1 -C 4） 碘 以产生式（II）的[ - 18 F]氟代卤代烷基（F）（CH 3） （II）其中n和X如对于式（I）化合物所定义，任选地随后（i）除去过量的 例如通过离子交换色谱法; 和/或（ii）除去有机溶剂。

公开(公告)号：US20060106219A1

公开(公告)日：2006-05-18

申请号：US10528645

申请日：2003-09-18

申请人： Frank Brady ,  Sajinder Luthra ,  Yongjun Zhao

发明人： Frank Brady ,  Sajinder Luthra ,  Yongjun Zhao

IPC分类号： A61K51/00 ,  C07D451/02 ,  C07F7/08

CPC分类号： C07B59/001 ,  C07C17/093 ,  C07C303/26

摘要： The invention provides a process for preparation of a fluorohaloalkane, preferably an [18F]fluorohaloalkane of formula (I) wherein X is halo and n is an integer of from 1 to 6; which comprises: reaction of the corresponding organosilicon compound of formula (II): wherein n is as defined for the compound of formula (I); and R′, R″, and R′″ are independently selected from C1-6 alkyl and C1-6 haloalkyl; and R″ may alternatively be the group: with a compound of formula (III): wherein X is as defined for the compound of formula (I) and Y is halo. Intermediates having use in such processes are also claimed.

摘要翻译： 本发明提供了制备式（I）的氟代卤代烷烃，优选其中X为卤素且n为1至6的整数的式（I）的[F 18 F]氟卤代烷烃的方法; 其包括：相应的式（II）的有机硅化合物的反应：其中n如对于式（I）的化合物所定义; 和R'，R“和R”'独立地选自C 1-6烷基和C 1-6卤代烷基; 和R“可以另选地为：与式（III）化合物：其中X如式（I）化合物所定义，Y是卤素。 也要求使用在这些方法中的中间体。