中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

68 records (took 0.036 seconds)

    BLADDER CANCER DETECTION AND MONITORING
    31.
    发明申请
    BLADDER CANCER DETECTION AND MONITORING 审中-公开
    乳腺癌检测和监测

    公开(公告)号：US20140303001A1

    公开(公告)日：2014-10-09

    申请号：US14204976

    申请日：2014-03-11

    Applicant: Myriad Genetics, Inc.

    Inventor： Stone Steve ,  Michael Perry ,  Alexander Gutin

    IPC: C12Q1/68

    CPC classification number: C12Q1/6886 ,  C12Q2600/156

    Abstract: Provided are molecular markers for detecting bladder cancer, especially recurrent bladder cancer, and methods of use thereof, including methods of monitoring for the recurrence of bladder cancer.

    Abstract translation: 提供用于检测膀胱癌，特别是复发性膀胱癌的分子标记及其使用方法，包括监测膀胱癌复发的方法。

    ELECTRONIC VARIANT CLASSIFICATION
    32.
    发明公开
    ELECTRONIC VARIANT CLASSIFICATION 审中-公开

    公开(公告)号：US20240282407A1

    公开(公告)日：2024-08-22

    申请号：US18646644

    申请日：2024-04-25

    Applicant: Myriad Genetics, Inc.

    Inventor： Dmitry Pruss ,  Brian Morris ,  Karla Bowles ,  Julie M. Eggington ,  Benjamin B. Roa ,  Alexander Gutin ,  Elisha Hughes

    IPC: G16B20/20 ,  G16B20/00

    CPC classification number: G16B20/20 ,  G16B20/00

    Abstract: A computer-implemented method is discussed that includes identifying, by a computer server system, stored electronic data that represents genetic sequencing for one or more genes for individuals in a population of patients who have submitted to genetic sequencing; generating, for each of multiple individuals and from the stored electronic data, probability data for the individuals and probability or weighting data, or both, for relatives of the individuals, the probability data representing likelihoods that a particular person corresponding to the probability data carries a deleterious mutation in a particular gene; and generating a score for a genetic variant, wherein the score is a function of probability or weighting data, or both, for the individuals and for relatives of the individuals, and the score represent a composite probability that a certain variant is a deleterious or benign variant.

    METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY
    40.
    发明申请
    METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY 审中-公开
    用于评估异常性损失的方法和材料

    公开(公告)号：US20170022569A1

    公开(公告)日：2017-01-26

    申请号：US15192497

    申请日：2016-06-24

    Applicant: Myriad Genetics, Inc.

    Inventor： Victor Abkevich ,  Alexander Gutin ,  Kirsten Timms ,  Jerry Lanchbury

    IPC: C12Q1/68 ,  A61K31/282 ,  A61K33/24

    CPC classification number: C12Q1/6886 ,  A61K31/282 ,  A61K33/24 ,  C12Q2600/106 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/158

    Abstract: This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.

    Abstract translation: 本文件提供了评估样品（例如癌细胞）中存在杂合性（LOH）特征丧失的方法和材料。 例如，提供了用于确定细胞（例如，癌细胞）是否包含LOH标记的方法和材料。 还提供了用于鉴别具有同源性定向修复（HDR）缺陷的细胞（例如癌细胞）的材料和方法以及用于鉴定可能对特定癌症治疗方案作出反应的癌症患者的材料和方法。

Patent Agency Ranking