公开(公告)号：US20240226434A1

公开(公告)日：2024-07-11

申请号：US18415379

申请日：2024-01-17

Applicant: Medtronic MiniMed, Inc.

Inventor： Benyamin Grosman ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Di Wu ,  Patrick E. Weydt ,  David Dunleavy ,  Ali Dianaty

IPC: A61M5/172

CPC classification number: A61M5/1723 ,  A61M2205/52 ,  A61M2230/201

Abstract: Techniques disclosed herein relate to closed-loop control in steady-state conditions. In some embodiments, the techniques may involve determining an amount of unmetabolized therapeutic substance in a patient; determining, based on a measurement of a physiological condition of the patient and a target value for the physiological condition, a first amount or rate of a basal dosage for delivery to the patient; adjusting, based on the amount of unmetabolized therapeutic substance, the first amount or rate of the basal dosage to determine a second amount or rate of the basal dosage; and causing delivery of the second amount or rate of the basal dosage based on communicating the second amount or rate in a delivery command.

公开(公告)号：US11839744B2

公开(公告)日：2023-12-12

申请号：US17179070

申请日：2021-02-18

Applicant: Medtronic MiniMed, Inc.

Inventor： Benyamin Grosman ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Di Wu ,  Patrick E. Weydt ,  David Dunleavy ,  Ali Dianaty

IPC: A61M5/172

CPC classification number: A61M5/1723 ,  A61M2205/52 ,  A61M2230/201

Abstract: Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.

公开(公告)号：US11744946B2

公开(公告)日：2023-09-05

申请号：US17179109

申请日：2021-02-18

Applicant: Medtronic MiniMed, Inc.

Inventor： Benyamin Grosman ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Di Wu ,  Patrick E. Weydt ,  David Dunleavy ,  Ali Dianaty

IPC: A61M5/172

CPC classification number: A61M5/1723 ,  A61M2205/52 ,  A61M2230/201

Abstract: Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.

公开(公告)号：US20230248910A1

公开(公告)日：2023-08-10

申请号：US18304174

申请日：2023-04-20

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Louis J. Lintereur ,  Anirban Roy ,  Benyamin Grosman ,  Patrick E. Weydt ,  Neha J. Parikh ,  Di Wu ,  Ali Dianaty

IPC: A61M5/172 ,  A61B5/145 ,  A61B5/00 ,  G16H20/17

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/4866 ,  G16H20/17 ,  A61B5/7275 ,  A61M2230/201 ,  A61M2205/3303 ,  A61M2205/52

Abstract: Techniques disclosed herein relate to safe correction boluses. In some embodiments, the techniques involve predicting a future glucose level that would result from delivery of a correction bolus. The techniques may also involve comparing the future glucose level to a threshold level for hypoglycemia. The techniques may further involve causing delivery of the correction bolus when the future glucose level is above the threshold level for hypoglycemia.

公开(公告)号：US11712520B2

公开(公告)日：2023-08-01

申请号：US17231583

申请日：2021-04-15

Applicant: Medtronic MiniMed, Inc.

Inventor： Louis J. Lintereur ,  Anirban Roy ,  Benyamin Grosman ,  Patrick E. Weydt ,  Neha J. Parikh ,  Di Wu ,  Ali Dianaty

IPC: A61M5/172 ,  A61B5/00 ,  G16H20/17 ,  G16H50/20 ,  A61B5/145

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/4866 ,  A61B5/7275 ,  G16H20/17 ,  G16H50/20 ,  A61M2205/3303 ,  A61M2205/52 ,  A61M2230/201

Abstract: Medical devices and related systems and operating methods are provided. A method of operating an infusion device capable of delivering fluid influencing a physiological condition to a patient involves obtaining an event indication, such as a meal indication, determining an initial bolus amount based on the event indication, and determining predicted values for the physiological condition of the patient during a time window into the future based at least in part on the initial bolus amount. When the predicted values violate a threshold during the time window, the control system identifies an adjusted bolus amount that results in the predicted values for the physiological condition satisfying the threshold during the time window from within a search space defined by the initial bolus amount and operates an actuation arrangement of the infusion device to deliver the adjusted bolus amount of the fluid to the patient.

公开(公告)号：US11660394B2

公开(公告)日：2023-05-30

申请号：US17122445

申请日：2020-12-15

Applicant: Medtronic MiniMed, Inc.

Inventor： Louis J. Lintereur ,  Anirban Roy ,  Benyamin Grosman ,  Patrick E. Weydt ,  Neha J. Parikh ,  Di Wu ,  Ali Dianaty

IPC: A61M5/172 ,  A61B5/145 ,  A61B5/00 ,  G16H20/17

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/4866 ,  A61B5/7275 ,  G16H20/17 ,  A61M2205/3303 ,  A61M2205/52 ,  A61M2230/201

Abstract: A method of controlling an insulin infusion device involves controlling the device to operate in an automatic basal insulin delivery mode, obtaining a blood glucose measurement for the user, and initiating a correction bolus procedure when: the measurement exceeds a correction bolus threshold value; and a maximum basal insulin infusion rate is reached during the automatic basal insulin delivery mode. The correction bolus procedure calculates an initial correction bolus amount, and scales the initial amount to obtain a final correction bolus amount, such that a predicted future blood glucose level resulting from simulated delivery of the final correction bolus amount exceeds a low blood glucose threshold level. The final amount is delivered to the user during operation in the automatic basal insulin delivery mode.

公开(公告)号：US20230044319A1

公开(公告)日：2023-02-09

申请号：US17744607

申请日：2022-05-13

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Huzefa F. Neemuchwala ,  Pratik Agrawal ,  Benyamin Grosman ,  Anirban Roy ,  Patrick E. Weydt ,  Louis J. Lintereur ,  Ali Dianaty ,  Yuxiang Zhong ,  Chantal M. McMahon

IPC: A61B5/00 ,  A61B5/145 ,  G16H20/17 ,  A61M5/172 ,  G16H50/20 ,  G06F16/28 ,  G06F16/22 ,  G06F16/332 ,  G16H20/70 ,  A61M5/142 ,  G16H50/50 ,  G16H50/30 ,  G16H20/10 ,  G16H50/70 ,  G16H20/30 ,  A61B5/11 ,  G16H10/60 ,  G16H40/63 ,  G16H20/60

Abstract: Infusion devices and related medical devices, patient data management systems, and methods are provided for monitoring a physiological condition of a patient. An exemplary infusion device includes an actuation arrangement operable to deliver fluid to a user, a communications interface to receive measurement data indicative of a physiological condition of the user, a sensing arrangement to obtain contextual measurement data, and a control system coupled to the actuation arrangement, the communications interface and the sensing arrangement to determine a command for autonomously operating the actuation arrangement in a manner that is influenced by the measurement data and the contextual measurement data and autonomously operate the actuation arrangement in accordance with the command to deliver the fluid to the user.

公开(公告)号：US20220313908A1

公开(公告)日：2022-10-06

申请号：US17222570

申请日：2021-04-05

Applicant: Medtronic MiniMed, Inc.

Inventor： Benyamin Grosman ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Di Wu ,  Patrick E. Weydt ,  David Dunleavy ,  Ali Dianaty

IPC: A61M5/172

Abstract: A processor-implemented method for closed-loop control in steady-state conditions includes determining, based on data including historical bolus information but excluding historical basal information, an amount of unmetabolized therapeutic substance in a patient; determining, based on a difference between a most recent measurement of a physiological condition of the patient and a target value for the physiological condition, a first amount or rate of a basal dosage for delivery to the patient; adjusting, based on the amount of unmetabolized therapeutic substance, the first amount or rate of the basal dosage to determine a second amount or rate of the basal dosage; and causing delivery of the second amount or rate of the basal dosage based on communicating the second amount or rate in a delivery command.

公开(公告)号：US20220257859A1

公开(公告)日：2022-08-18

申请号：US17179109

申请日：2021-02-18

Applicant: Medtronic MiniMed, Inc.

Inventor： Benyamin Grosman ,  Louis J. Lintereur ,  Anirban Roy ,  Neha J. Parikh ,  Di Wu ,  Patrick E. Weydt ,  David Dunleavy ,  Ali Dianaty

IPC: A61M5/172

Abstract: Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.

公开(公告)号：US20220249772A1

公开(公告)日：2022-08-11

申请号：US17661147

申请日：2022-04-28

Applicant: Medtronic MiniMed, Inc.

Inventor： Anirban Roy

IPC: A61M5/172 ,  A61M5/145

Abstract: A system for controlling fluid delivery includes one or more processors, and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of: identifying a residual value indicative of a difference between a first value and a second value, the first value corresponding to a physiological condition of a patient before delivery of a bolus amount of fluid, and the second value corresponding to a physiological condition of the patient after delivery of the bolus amount of the fluid, determining a ratio adjustment factor based on the residual value, and determining, based on the ratio adjustment factor, an updated value for a ratio that influences delivery of bolus amounts of the fluid.