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公开(公告)号：US12109391B2
公开(公告)日：2024-10-08
申请号：US18046863
申请日：2022-10-14
发明人： Ian B. Hanson , Paul F. Bente, IV
CPC分类号： A61M5/172 , A61M5/1413 , A61M5/14248 , A61M5/1456 , A61M5/1684 , A61M5/5086 , A61M2005/14268 , A61M2205/3389 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6027 , A61M2205/6036 , A61M2205/6045 , A61M2205/6054 , A61M2205/6063 , A61M2205/6072 , A61M2205/6081 , Y10T29/49117
摘要： A medical device includes a first housing portion (FHP) and a second housing portion (SHP) configured to be to be movable relative to each other from a first position to operatively engage at a second position to couple at least one of a drive device and a needle-inserting device supported by one of the FHP and the SHP to a reservoir supported by the other of the FHP and the SHP. Electronic circuitry configured to detect at least one of a first magnetic interaction between a magnet and at least one of a first magnetically attractive material and a first magnet-responsive device and a second magnetic interaction between the magnet and at least one of a second magnetically attractive material and a second magnet-responsive device, and to provide a signal or a change in state in response to detecting at least one of the interactions.
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公开(公告)号：US12109023B2
公开(公告)日：2024-10-08
申请号：US18350482
申请日：2023-07-11
IPC分类号： A61B5/1486 , A61B5/00 , A61B5/145 , C08G18/32 , C08G18/40 , C08G18/44 , C08G18/50 , C08G18/61 , C08G18/72 , C08G18/73 , C08G18/76 , C08L75/12 , C08G77/448 , C08G77/458
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/686 , C08G18/3228 , C08G18/4009 , C08G18/44 , C08G18/5024 , C08G18/61 , C08G18/72 , C08G18/724 , C08G18/73 , C08G18/7671 , C08L75/12 , A61B5/6876 , A61B2562/125 , C08G77/448 , C08G77/458
摘要： Embodiments of the invention provide compositions useful in analyte sensors as well as methods for making and using such compositions and sensors. In typical embodiments of the invention, the sensor is a glucose sensor comprising an analyte modulating membrane formed from a polymeric reaction mixture formed to include limiting amounts of catalyst and/or polycarbonate compounds so as to provide such membranes with improved material properties such as enhanced thermal and hydrolytic stability.
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3.发明公开公开(公告)号：US20240298932A1
公开(公告)日：2024-09-12
申请号：US18664947
申请日：2024-05-15
发明人： Ashwin K. Rao , Rebecca K. Gottlieb , Quyen B. Ong
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1477 , A61B5/1486 , C07K14/62 , C12Q1/00 , G01N33/52 , G01N33/66
CPC分类号： A61B5/14532 , A61B5/14517 , A61B5/1486 , G01N33/526 , G01N33/66 , A61B5/14539 , A61B5/14546 , A61B5/1477 , A61B5/6833 , C07K14/62 , C12Q1/006
摘要： Described here are patches and methods for measuring glucose in sweat (and tears and the like). In general, the patches comprise an adhesive layer adapted to bond to skin of an individual, a substrate layer disposed over the adhesive layer and comprising a glucose sensing complex including a chromogen that changes color in the presence of certain concentrations of glucose, and a cover. In typical embodiments, the substrate layer has elements formed to direct and accumulate sweat that migrates from the skin of the individual to the glucose sensing complex. Methods of using the invention can comprise cleaning the skin surface, collecting sweat in a patch comprising this microfluidic constellation of elements, and observing concentrations of glucose collected in the sweat, for example either visually, or by using a smartphone or other computer processing device.
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公开(公告)号：US20240298929A1
公开(公告)日：2024-09-12
申请号：US18429804
申请日：2024-02-01
CPC分类号： A61B5/14503 , A61B90/08 , A61B2090/0807 , A61B2560/0462 , A61B2562/12 , A61B2562/16 , A61B2562/18
摘要： A sensor device includes a housing configured to be secured to a patient and a seal structure located within the housing. A sensor probe having at least one substrate is supported by the housing. The substrate has a first length portion and a second length portion. The first length portion is external to the housing and is configured to be inserted into the patient when the housing is secured to the patient. The second length portion is in or on the housing and has a section that extends through the seal structure. That section has at least one side edge having an undulating edge pattern that enhances a seal effect of the seal structure at the section of the second length portion of the at least one substrate. The undulating edge pattern may be an edge wave pattern having a plurality of peaks or a plurality of valleys.
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公开(公告)号：US12082929B2
公开(公告)日：2024-09-10
申请号：US17135766
申请日：2020-12-28
发明人： Ning Yang , Raghavendhar Gautham , Rajiv Shah
IPC分类号： A61B5/1495 , A61B5/00 , A61B5/0537 , A61B5/0538 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/1486 , A61M5/142 , A61M5/158 , A61M5/172 , G01N27/02 , G01N27/416 , G01N33/49 , G01N33/66 , G01N33/96 , G01R35/00
CPC分类号： A61B5/1495 , A61B5/0537 , A61B5/0538 , A61B5/14503 , A61B5/14532 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/4839 , A61B5/6849 , A61B5/6852 , A61B5/7203 , A61B5/7221 , A61B5/7225 , A61B5/7242 , A61B5/746 , A61M5/14276 , A61M5/1582 , A61M5/1723 , G01N27/026 , G01N27/028 , G01N27/416 , G01N27/4163 , G01N33/49 , G01N33/66 , G01N33/96 , G01R35/00 , G01R35/005 , A61B2562/0214 , A61B2562/04 , A61M5/14244 , A61M2005/1726
摘要： A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.
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公开(公告)号：US12082924B2
公开(公告)日：2024-09-10
申请号：US16944450
申请日：2020-07-31
发明人： David Yueh-Hua Choy , Ellis Garai , Melissa Tsang , Anuj M. Patel
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1495
CPC分类号： A61B5/14532 , A61B5/1495 , A61B5/4839 , A61B2560/0214 , A61B2560/0223 , A61B2562/166 , A61B2562/227
摘要： An analyte sensor apparatus including a sensing portion including one or more electrodes including a working electrode and one or more contacts for electrically connecting the sensor portion to control circuitry (e.g., a printed circuit board assembly, PCBA); and a circuit comprising the one or more contacts; wherein the circuit detects an electrical connection between the control circuitry without requiring exposure of the sensing portion to a fluid.
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公开(公告)号：US12076533B2
公开(公告)日：2024-09-03
申请号：US17645693
申请日：2021-12-22
发明人： Boyi Jiang , Yuxiang Zhong , Pratik J. Agrawal
CPC分类号： A61M5/1723 , A61M5/1452 , G16H10/60 , G16H20/17 , A61M2205/50 , A61M2205/8206 , A61M2230/201
摘要： A processor-implemented method includes identifying a reference insulin absorption curve for a patient based on demographic data of the patient, identifying a contextual adjustment factor based on current contextual information for the patient, obtaining an adjusted insulin absorption curve based on the reference insulin absorption curve and the contextual adjustment factor, and causing insulin delivery to the patient based on the adjusted insulin absorption curve.
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8.发明公开公开(公告)号：US20240285855A1
公开(公告)日：2024-08-29
申请号：US18644410
申请日：2024-04-24
发明人： Louis J. Lintereur , Alexander S. Campbell , Dmytro Y. Sokolovskyy , Neha J. Parikh , Maria Diana Miller
CPC分类号： A61M5/1723 , G16H10/40 , G16H20/17 , G16H40/67 , A61M2205/18 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/702 , A61M2230/201
摘要： Techniques disclosed herein relate to continuous analyte sensor quality measures. In some embodiments, the techniques may involve obtaining a sensor-generated value that is indicative of a physiological characteristic of a user of a medical device. The techniques may further involve causing, in response to obtaining a sensor quality metric that indicates accuracy of the sensor-generated value, configuration of a quality-specific operating mode of the medical device, the quality-specific operating mode comprising regulation of basal and bolus deliveries of a fluid medication based on the obtained sensor quality metric.
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9.发明公开公开(公告)号：US20240285199A1
公开(公告)日：2024-08-29
申请号：US18643565
申请日：2024-04-23
发明人： Keith Nogueira , Peter Ajemba , Michael E. Miller , Steven C. Jacks , Jeffrey Nishida , Andy Y. Tsai , Andrea Varsavsky
IPC分类号： A61B5/1495 , A61B5/00 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/11 , A61B5/145 , A61B5/1455 , A61B5/1468 , A61B5/1486 , G01N27/02 , G06N5/022 , G16H20/17 , G16H40/40 , G16H50/30 , G16H50/70
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/1468 , A61B5/14865 , A61B5/6849 , A61B5/686 , G01N27/026 , G06N5/022 , G16H20/17 , G16H40/40 , G16H50/30 , G16H50/70 , A61B5/0075 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/1118 , A61B5/14546 , A61B5/1455 , A61B5/7203 , A61B5/7221 , A61B5/7267 , A61B5/742 , A61B2505/07 , A61B2560/0223 , A61B2560/0252 , A61B2560/0257 , A61B2562/028 , A61B2562/029 , A61B2562/164
摘要： A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.
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公开(公告)号：US12070576B2
公开(公告)日：2024-08-27
申请号：US17188409
申请日：2021-03-01
发明人： Roger E. Smith
CPC分类号： A61M5/1452 , A61M5/1413 , A61M5/14244 , A61M5/14248 , A61M2005/14268 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8243 , A61M2209/01
摘要： Ambulatory infusion pumps, durable assemblies, and disposable assemblies, including energy sources, reservoirs, baseplates, and related components therefor, as well as component combinations and related methods.
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