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    Infusion systems and related personalized bolusing methods
    31.
    发明授权
    Infusion systems and related personalized bolusing methods 有权

    公开(公告)号：US11191899B2

    公开(公告)日：2021-12-07

    申请号：US16547512

    申请日：2019-08-21

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Anirban Roy ,  Benyamin Grosman ,  Neha J. Parikh ,  Di Wu ,  Louis J. Lintereur

    IPC: A61M5/172 ,  A61M5/142 ,  G16H20/17

    Abstract: Infusion systems, infusion devices, and related operating methods are provided. A method of operating an infusion device involves obtaining an input qualitative event attribute, such as a meal size, obtaining a quantitative event attribute associated with the qualitative event attribute that is representative of a subset of historical events for a patient associated with the qualitative event attribute, such as a representative carbohydrate amount for the qualitative meal size, and thereafter determine a dosage of fluid based at least in part on the quantitative event attribute and operate the infusion device to deliver the dosage of the fluid to the patient.

    SENSOR MODEL SUPERVISOR FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM
    34.
    发明申请
    SENSOR MODEL SUPERVISOR FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM 审中-公开

    公开(公告)号：US20190076600A1

    公开(公告)日：2019-03-14

    申请号：US16156801

    申请日：2018-10-10

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Benyamin Grosman ,  Di Wu ,  Anirban Roy ,  Neha J. Parikh

    IPC: A61M5/172 ,  A61B5/145 ,  A61B5/00 ,  A61M5/142 ,  G16H20/17

    Abstract: An insulin infusion device includes a processor architecture, and a memory element that stores executable instructions to perform a method of controlling delivery of insulin to a user. The method operates the device in a closed-loop mode to deliver insulin, obtains patient-specific parameters for a current time sample, and estimates a plasma insulin value and a blood glucose value for the user based on at least some of the patient-specific parameters. The estimating is also based on a previously estimated plasma insulin value obtained for a previous time sample, and a previously estimated blood glucose value obtained for the previous time sample. A predicted sensor glucose value is generated for the current time sample, and the closed-loop mode or a safe basal mode is selected for controlling operation of the insulin infusion device in accordance with the selected mode.

    METHODS FOR PROVIDING SENSOR SITE ROTATION FEEDBACK AND RELATED INFUSION DEVICES AND SYSTEMS
    37.
    发明申请
    METHODS FOR PROVIDING SENSOR SITE ROTATION FEEDBACK AND RELATED INFUSION DEVICES AND SYSTEMS 审中-公开
    提供传感器站点旋转反馈和相关输入设备和系统的方法

    公开(公告)号：US20170049962A1

    公开(公告)日：2017-02-23

    申请号：US15240720

    申请日：2016-08-18

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Neha J. Parikh ,  Rebecca K. Gottlieb ,  Benyamin Grosman ,  Anirban Roy ,  Di Wu

    IPC: A61M5/172 ,  A61B5/00 ,  A61B5/145 ,  A61M5/168 ,  G06F19/00

    CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/684 ,  A61B5/743 ,  A61B5/748 ,  A61M5/14244 ,  A61M5/16877 ,  A61M2005/14208 ,  A61M2205/502 ,  A61M2205/52 ,  G06F19/00 ,  G06F19/3468 ,  G16H10/60 ,  G16H20/17 ,  G16H40/63 ,  G16H50/70

    Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves identifying a current site location on the body of the user associated with a sensing arrangement providing sensed measurements of a physiological condition in the body of the user at the current site location, determining one or more performance metrics associated with the current site location corresponding to operation of the infusion device to deliver the fluid in response to the sensed measurements, and providing sensor site feedback in a manner that is influenced by the one or more performance metrics. In one or more embodiments, the sensor site feedback includes recommended sensor site locations for rotation or replacement of the sensing arrangement determined based on historical data associated with the user for different sensor site locations.

    Abstract translation: 提供输液系统，输液装置和相关操作方法。 操作输注装置以将流体递送到使用者的身体的示例性方法包括识别与感测装置相关联的用户身体上的当前位置位置，其提供在当前的用户体内的生理状况的感测测量 站点位置，确定与当前位置位置相关联的与所述输注装置的操作相关联的一个或多个性能指标，以响应于所感测的测量结果输送流体，并且以受一个或多个性能影响的方式提供传感器位置反馈 指标 在一个或多个实施例中，传感器站点反馈包括用于旋转或替换感测装置的推荐传感器位置位置，其基于与用户不同的传感器位置位置相关联的历史数据确定。

    Insulin on board compensation for a closed-loop insulin infusion system
    39.
    发明授权
    Insulin on board compensation for a closed-loop insulin infusion system 有权
    胰岛素对闭环胰岛素输注系统的补偿

    公开(公告)号：US09364609B2

    公开(公告)日：2016-06-14

    申请号：US13870902

    申请日：2013-04-25

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： Desmond Barry Keenan ,  John J. Mastrototaro ,  Benyamin Grosman ,  Neha J. Parikh ,  Anirban Roy

    IPC: G06Q10/00 ,  A61M5/172 ,  A61B5/00 ,  A61B5/145 ,  G06F19/00

    CPC classification number: A61M5/1723 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/746 ,  A61M5/172 ,  A61M2205/18 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/582 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468

    Abstract: An electronic controller for an insulin infusion device includes a processor architecture and at least one memory element. The memory element stores executable instructions that, when executed by the processor architecture, provide an insulin on board (IOB) compensation module to estimate a current IOB value that indicates an amount of active insulin in the body of the user, calculate an IOB rate based at least in part on the estimated current IOB value, determine an adjusted insulin infusion rate based at least in part on the calculated IOB rate and an uncompensated insulin infusion rate, select a final insulin infusion rate for the device, and provide the selected final insulin infusion rate to regulate delivery of insulin by the device.

    Abstract translation: 一种用于胰岛素输注装置的电子控制器包括处理器架构和至少一个存储元件。 存储器元件存储可执行指令，当由处理器体系结构执行时，该指令提供了一种岛内胰岛素（IOB）补偿模块，以估计当前IOB值，该当前IOB值表示用户身体中的活动胰岛素的量，基于IOB率计算 至少部分地基于估计的当前IOB值，至少部分地基于所计算的IOB速率和未补偿的胰岛素输注速率来确定调整的胰岛素输注速率，选择装置的最终胰岛素输注速率，并提供所选择的最终胰岛素 输液速率来调节胰岛素的输送。

    SAFEGUARDING TECHNIQUES FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM
    40.
    发明申请
    SAFEGUARDING TECHNIQUES FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM 有权
    封闭式胰岛素输注系统的保护技术

    公开(公告)号：US20140066887A1

    公开(公告)日：2014-03-06

    申请号：US13966109

    申请日：2013-08-13

    Applicant: Medtronic Minimed, Inc.

    Inventor： John J. Mastrototaro ,  Benyamin Grosman ,  Neha J. Parikh ,  Anirban Roy ,  Desmond Barry Keenan

    IPC: A61M5/172

    CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/4839 ,  A61B2560/0223 ,  G06F19/00 ,  G06F19/3468

    Abstract: Processor-implemented methods of controlling an insulin infusion device for a user are provided here. A first method obtains and analyzes calibration factors (and corresponding timestamp data) for a continuous glucose sensor, and regulates entry into a closed-loop operating mode of the infusion device based on the calibration factors and timestamp data. A second method obtains a most recent sensor glucose value and a target glucose setpoint value for the user at the outset of the closed-loop mode. The second method adjusts the closed-loop insulin infusion rate over time, in response to the sensor glucose value and the setpoint value. A third method calculates an upper insulin limit that applies to the insulin infusion rate during the closed-loop mode. The insulin limit is calculated based on a fasting blood glucose value of the user, a total daily insulin value of the user, and fasting insulin delivery data for the user.

    Abstract translation: 这里提供了用于控制用户的胰岛素输注装置的处理器实现的方法。 第一种方法获得和分析连续葡萄糖传感器的校准因子（和对应的时间戳数据），并且基于校准因子和时间戳数据来调节进入输注装置的闭环操作模式。 第二种方法在闭环模式开始时获得用户最近的传感器葡萄糖值和目标葡萄糖设定值。 第二种方法是响应于传感器葡萄糖值和设定点值来调整随时间推移的闭环胰岛素输注速率。 第三种方法计算在闭环模式期间适用于胰岛素输注速率的胰岛素上限。 基于用户的空腹血糖值，用户的总每日胰岛素值和用户的空腹胰岛素递送数据来计算胰岛素限制。

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