公开(公告)号：US20240358280A1

公开(公告)日：2024-10-31

申请号：US18765375

申请日：2024-07-08

申请人： BIONIME CORPORATION

发明人： Li-Kang HUANG ,  Chieh-Hsing CHEN ,  Tsung-Da LI

IPC分类号： A61B5/145 ,  A61B17/34

CPC分类号： A61B5/14503 ,  A61B17/3417 ,  A61B17/3468 ,  A61B2017/3454 ,  A61B2560/063

摘要： An insertion needle structure includes a needle sharp and a needle body. The needle body is integrally connected to the needle sharp and has a receiving space for receiving the biosensor. The needle body includes a base wall, two side walls, two slope sections and two curved connecting sections. The side walls are located at two sides of the base wall, respectively, the side walls are at least partially nonparallel, and each of the side walls is at least partially flat. Each of the slope sections is connected between each of the side walls and the needle sharp, and each of the slope sections is curved. Each of the curved connecting sections is connected between each of the side walls and the base wall and between each of the slope sections and the base wall. The needle sharp extends from the base wall and the curved connecting sections.

公开(公告)号：US20240342503A1

公开(公告)日：2024-10-17

申请号：US18133927

申请日：2023-04-12

申请人： Becton, Dickinson and Company

发明人： Amanda Lingle ,  Megan Brooks ,  Morgan Izykowski ,  David Colton Jackson ,  Joseph Aamodt

IPC分类号： A61N5/06 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0538 ,  A61B5/145

CPC分类号： A61N5/0624 ,  A61B5/01 ,  A61B5/0538 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/6852 ,  A61N5/0601 ,  A61N2005/063 ,  A61N2005/0651

摘要： An indwelling medical device with stimuli-responsive antimicrobial properties. The medical device includes a polymeric substrate having one or more light-responsive antimicrobial compounds. The medical device includes a light source to provide light to the polymeric substrate and a sensor to detect infection or bacterial colonization. A controller is connected to the light source and to the sensor. The controller controls operation of the sensor and receives sensing signals from the sensor. The controller activates the light source in response to infection detection and release the antimicrobial compound. The light-responsive antimicrobial compound may include a nitric oxide donor, such as S-nitroso-n-acetylpenacillamine, S-nitrosoglutathione, or N-diazeniumdiolate (NONOate). The light-responsive antimicrobial compound may include a photocatalyst metal oxide, such as ZnO, CuO, or TiO2. The light-responsive antimicrobial compound may include a photosensitive dye, such as crystal violet, methylene blue ethyl violet, rose bengal, or malachite green.

公开(公告)号：US20240341643A1

公开(公告)日：2024-10-17

申请号：US18752091

申请日：2024-06-24

申请人： Roche Diabetes Care, Inc.

发明人： Helmut Walter

IPC分类号： A61B5/1473 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  B08B5/00 ,  B08B7/00

CPC分类号： A61B5/1473 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/6849 ,  B08B5/00 ,  B08B7/0035 ,  A61B5/688 ,  A61B2560/063 ,  A61B2562/166 ,  A61B2562/242

摘要： Medical devices and methods are disclosed for detecting an analyte in a body fluid. The medical device comprises an analyte sensor having an insertable portion adapted for insertion into body tissue of a user. An insertion cannula receives the analyte sensor therein. A housing forms a sealed sensor compartment receiving an insertable portion of the analyte sensor. The sealed sensor compartment comprises a detachable upper cap and a detachable lower cap. The detachable lower cap is configured for detachment before sensor insertion. The cannula is attached to the detachable upper cap, wherein the detachable upper cap is configured for detachment after insertion, thereby removing the insertion cannula. The analyte sensor is operably connected to an electronics unit comprising an interconnect device with at least one electronic component attached thereto

公开(公告)号：US20240341633A1

公开(公告)日：2024-10-17

申请号：US18642331

申请日：2024-04-22

申请人： Senseonics, Incorporated

发明人： Joon Chatterjee ,  Venkata Velvadapu ,  Mark Mortellaro ,  Philip Huffstetler

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/1486 ,  A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  C08F283/06 ,  C08K5/55 ,  G01N21/75 ,  G01N21/77 ,  G01N33/50

CPC分类号： A61B5/14503 ,  A61B5/14546 ,  A61L31/041 ,  A61L31/145 ,  A61L31/16 ,  C08F283/06 ,  C08K5/55 ,  G01N21/75 ,  G01N21/77 ,  G01N33/50 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/1459 ,  A61B5/14735 ,  A61B5/14865

摘要： A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more compounds having metal chelating moieties that reduce degradation of the analyte indicator.

公开(公告)号：US20240325758A1

公开(公告)日：2024-10-03

申请号：US18503504

申请日：2023-11-07

申请人： Cardionomic, Inc.

发明人： Steven L. Waldhauser ,  Steven D. Goedeke

IPC分类号： A61N1/36 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/145 ,  A61B5/25 ,  A61B5/318 ,  A61B7/02 ,  A61N1/02 ,  A61N1/05

CPC分类号： A61N1/36114 ,  A61N1/025 ,  A61N1/05 ,  A61N1/056 ,  A61N1/36139 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/25 ,  A61B5/318 ,  A61B5/6869 ,  A61B7/023 ,  A61B2560/0223 ,  A61B2562/0219

摘要： A method of facilitating therapeutic neuromodulation of a heart of a patient includes positioning an electrode in a pulmonary artery, positioning a sensor in vasculature, delivering via a stimulation system first and second electrical signals of a series of electrical signals to the electrode. The second electrical signal differs from the first electrical signal by a magnitude of a first parameter of a plurality of parameters. The method includes determining, via the sensor, sensor data indicative of one or more heart activity properties in response to the delivery of the series of electrical signals, and delivering a therapeutic neuromodulation signal to the pulmonary artery using selected electrical parameters. The selected electrical parameters include a selected magnitude of the first parameter. The selected magnitude of the first parameter is based at least partially on the sensor data. The therapeutic neuromodulation signal increases heart contractility.

公开(公告)号：US20240293050A1

公开(公告)日：2024-09-05

申请号：US18646451

申请日：2024-04-25

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  Maria Noel Brown Wells ,  John Patrick Majewski ,  Leah Morta Edra ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486

CPC分类号： A61B5/14532 ,  A61B5/14503 ,  A61B5/683 ,  A61B5/6833 ,  A61B5/0004 ,  A61B5/0015 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/6849 ,  A61B2560/045

摘要： Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US12076145B2

公开(公告)日：2024-09-03

申请号：US16259157

申请日：2019-01-28

申请人： Abbott Diabetes Care Inc.

发明人： Kuan-Chou Chen ,  Tianmei Ouyang ,  Stephen Oja ,  Benjamin Feldman ,  Hyun Cho ,  Lam Tran ,  Mark Eshoo

IPC分类号： A61B5/1486 ,  A61B5/145 ,  G01N27/327

CPC分类号： A61B5/1486 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/14503 ,  G01N27/3271

摘要： A lactate-responsive enzyme may form the basis for lactate detection and quantification using an electrochemical analyte sensor. Various features may be incorporated within an analyte sensor containing a lactate-responsive enzyme, particularly lactate oxidase, to improve sensitivity and response stability of the analyte sensor. Such analyte sensors may comprise: a working electrode having an active area disposed thereon, and a mass transport limiting membrane overcoating at least the active area upon the working electrode. The active area comprises at least a polymer, an albumin, and a lactate-responsive enzyme that is covalently bonded to the polymer. The mass transport limiting membrane may comprise at least a crosslinked polyvinylpyridine homopolymer or copolymer. The analyte sensors may determine a lactate concentration in a biological fluid, particularly in vivo, which may be correlated to various physiological conditions.

公开(公告)号：US12075980B2

公开(公告)日：2024-09-03

申请号：US18099480

申请日：2023-01-20

申请人： The George Washington University ,  460Medical, Inc.

发明人： Omar Amirana ,  Kenneth C. Armstrong ,  Matthew W. Kay ,  Marco A. Mercader ,  Terrance J. Ransbury ,  Narine Sarvazyan

IPC分类号： A61B1/04 ,  A61B1/00 ,  A61B1/05 ,  A61B1/06 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1459 ,  A61B18/00 ,  A61B18/14 ,  A61B90/00 ,  A61B90/30 ,  A61B90/35 ,  A61B18/02 ,  A61B34/30

CPC分类号： A61B1/043 ,  A61B1/00009 ,  A61B1/00045 ,  A61B1/00082 ,  A61B1/00186 ,  A61B1/05 ,  A61B1/0638 ,  A61B1/0676 ,  A61B1/0684 ,  A61B5/004 ,  A61B5/0044 ,  A61B5/0084 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/6853 ,  A61B18/00 ,  A61B18/1492 ,  A61B90/30 ,  A61B90/35 ,  A61B90/361 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2034/301 ,  A61B2090/365 ,  Y02A90/10

摘要： Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue comprising: a catheter having a distal end and a proximal end; an inflatable balloon disposed about the distal end of the catheter; and an optical housing extending from the distal end of the catheter into the balloon, the optical housing being configured to position inside the balloon a light source for illuminating a tissue outside the balloon and a camera for imaging the illuminated tissue.

公开(公告)号：US20240277932A1

公开(公告)日：2024-08-22

申请号：US18638352

申请日：2024-04-17

申请人： Medtronic MiniMed, Inc.

发明人： Benyamin Grosman ,  Di Wu ,  Anirban Roy ,  Neha J. Parikh

IPC分类号： A61M5/172 ,  A61B5/00 ,  A61B5/145 ,  A61M5/142 ,  G16H20/17 ,  G16Z99/00

CPC分类号： A61M5/1723 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/746 ,  A61M5/14244 ,  G16H20/17 ,  G16Z99/00 ,  A61M2005/14208 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/201

摘要： Techniques related to temporary setpoint values are disclosed. The techniques may involve causing operation of a fluid delivery device in a closed-loop mode for automatically delivering fluid based on a difference between a first setpoint value and an analyte concentration value during operation of the fluid delivery device in the closed-loop mode. Additionally, the techniques may involve obtaining a second setpoint value. The second setpoint value may be a temporary setpoint value to be used for a period of time to regulate fluid delivery, and the second setpoint value may be greater than the first setpoint value. The techniques may further involve causing operation of the fluid delivery device for automatically reducing fluid delivery for the period of time based on the second setpoint value.

公开(公告)号：US20240277262A1

公开(公告)日：2024-08-22

申请号：US18443761

申请日：2024-02-16

申请人： ABBOTT DIABETES CARE INC.

发明人： Vivek S. Rao ,  Joshua Lindsay ,  Matthew Simmons ,  Steven T. Mitchell

IPC分类号： A61B5/145 ,  A61B5/00

CPC分类号： A61B5/14503 ,  A61B5/6849 ,  A61B2560/063

摘要： Systems, devices and methods are provided for inserting at least a portion of a sensor for sensing an analyte level in a bodily fluid of a subject. In particular, disclosed herein are various embodiments of reset tools for resetting an insertion apparatus, and containers for storing an analyte monitoring assembly. The analyte monitoring assembly can be a combination of components used for monitoring an analyte of the subject. The containers described herein can be used to load an analyte monitoring assembly into an insertion apparatus. The insertion apparatus can then be used to insert at least a portion of the sensor into the subject's skin. The insertion apparatus can be reusable.