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公开(公告)号：US12064599B2
公开(公告)日：2024-08-20
申请号：US17394121
申请日：2021-08-04
发明人： Di Wu , Rebecca K. Gottlieb , Benyamin Grosman , Anirban Roy , Neha J. Parikh , Ohad Cohen
CPC分类号： A61M5/1723 , A61B5/14532 , A61M5/14244 , G16H20/17 , G16H40/63 , G16H50/20 , G16H50/50 , A61M2005/14208 , A61M2205/50 , A61M2205/581 , A61M2205/583
摘要： Disclosed herein are techniques related to management of insufficient hypoglycemia response. In some embodiments, the techniques may involve obtaining an amount of insulin remaining in a body of a patient. The techniques may involve also obtaining a quantity of insulin needed by the patient within a future time period. Additionally, the techniques may involve identifying a condition in which the patient's glucose level will continue to decrease during the future time period despite suspension of basal insulin dosage delivery. The condition may be identified based on determining that the amount of insulin remaining in the body is greater than the quantity of insulin needed by the patient within the future time period. Furthermore, the techniques may involve, responsive to identifying the condition, causing performance of an action for preventing the patient's glucose level from falling into a hypoglycemic range in combination with the suspension of basal insulin dosage delivery.
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公开(公告)号：US11654233B2
公开(公告)日：2023-05-23
申请号：US17307886
申请日：2021-05-04
发明人： Chia-Hung Chiu , Hsifu Wang , Rebecca K. Gottlieb
IPC分类号： A61M5/158 , A61M25/00 , A61L29/06 , A61M39/02 , A61M5/142 , A61M39/08 , A61L29/04 , A61M25/06 , A61B17/34
CPC分类号： A61M5/158 , A61L29/041 , A61L29/06 , A61M5/142 , A61M5/14248 , A61M25/0009 , A61M25/0043 , A61M39/02 , A61M39/08 , A61B17/3415 , A61B2017/3454 , A61M25/065 , A61M2005/1585 , A61M2005/1587 , A61M2025/0059
摘要： An insertion set system includes a base configured to be secured to a patient, and a flexible tubing on the base. The flexible tubing has a distal end portion forming a cannula to be inserted into the patient. An inserter having a needle is received by the base. The needle has a channel in which the distal end portion of the flexible tubing is received. The needle is able to slide relative to the flexible tubing, to selectively withdraw the needle off of the distal end portion of the flexible tubing. The base may include a passage for fluid flow arranged transverse to the axial dimension of the distal end portion of the flexible tubing.
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公开(公告)号：US11612686B2
公开(公告)日：2023-03-28
申请号：US16892082
申请日：2020-06-03
发明人： Chia-Hung Chiu , Peter Schultz , Gayane R. Voskanyan , Hsifu Wang , Rebecca K. Gottlieb , Kenneth D. Warnock , Ricardo Juarez Martinez
IPC分类号： A61M5/14 , A61M5/142 , A61M5/172 , A61B5/00 , A61B5/145 , A61B5/1473 , A61M5/20 , A61M5/00 , A61M5/158 , A61M5/145
摘要： Disclosed is a medical device component for delivering medication fluid to a patient. The medical device component includes a fluid infusion device to regulate delivery of medication fluid, a body-mountable base unit, and a top cover assembly that is removably couplable to the base unit and to the fluid infusion device. The base unit includes a cannula to deliver medication fluid under the control of the fluid infusion device, and a physiological analyte sensor to measure a physiological characteristic. The base unit also includes an electronics assembly electrically connected to sensor leads to obtain measurements in the analog domain, to convert measurements into digital sensor data, and to communicate conditioned digital sensor data to the fluid infusion device. The top cover assembly is configured to provide both fluid and electrical connections for the base unit, by way of an infusion tube having sensor conductors integrated therein or otherwise associated therewith.
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公开(公告)号：US20220336100A1
公开(公告)日：2022-10-20
申请号：US17854077
申请日：2022-06-30
IPC分类号： G16H40/67 , G16H40/63 , A61B90/00 , A61M5/172 , G16H20/30 , G16H20/60 , G06T19/00 , G16H20/17 , G06V20/20
摘要： The disclosed techniques involve identifying a current state of a user interface of a medical device based at least in part on a portion of the medical device captured by an imaging device. The techniques also involve generating guidance information pertaining to the current state of the user interface. The techniques further involve presenting a guidance overlay including the guidance information pertaining to the current state of the user interface.
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公开(公告)号：US20210128834A1
公开(公告)日：2021-05-06
申请号：US17149419
申请日：2021-01-14
发明人： Neha J. Parikh , Anirban Roy , Benyamin Grosman , Rebecca K. Gottlieb , Di Wu
摘要： Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.
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公开(公告)号：US10894125B2
公开(公告)日：2021-01-19
申请号：US16162277
申请日：2018-10-16
发明人： Neha J. Parikh , Anirban Roy , Benyamin Grosman , Rebecca K. Gottlieb , Di Wu
摘要： Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.
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公开(公告)号：US20210003564A1
公开(公告)日：2021-01-07
申请号：US17025999
申请日：2020-09-18
发明人： Ashwin K. Rao , Rebecca K. Gottlieb , Quyen Ong
摘要： Devices, patch sensors, and methods for detecting a ketone body are disclosed. An exemplary device includes a collection apparatus for collecting a sample amount of interstitial fluid and a ketone body indicator having an initial negative state and having a positive state when at least a threshold value of the ketone body is collected in the sample amount.
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公开(公告)号：US10709834B2
公开(公告)日：2020-07-14
申请号：US15842800
申请日：2017-12-14
发明人： Chia-Hung Chiu , Peter Schultz , Gayane R. Voskanyan , Hsifu Wang , Rebecca K. Gottlieb , Kenneth D. Warnock , Ricardo Juarez Martinez
IPC分类号： A61M5/14 , A61M5/142 , A61M5/172 , A61B5/00 , A61B5/145 , A61B5/1473 , A61M5/20 , A61M5/00 , A61M5/158 , A61M5/145
摘要： Disclosed is a medical device component for delivering medication fluid to a patient. The medical device component includes a fluid infusion device to regulate delivery of medication fluid, a body-mountable base unit, and a top cover assembly that is removably couplable to the base unit and to the fluid infusion device. The base unit includes a cannula to deliver medication fluid under the control of the fluid infusion device, and a physiological analyte sensor to measure a physiological characteristic. The base unit also includes an electronics assembly electrically connected to sensor leads to obtain measurements in the analog domain, to convert measurements into digital sensor data, and to communicate conditioned digital sensor data to the fluid infusion device. The top cover assembly is configured to provide both fluid and electrical connections for the base unit, by way of an infusion tube having sensor conductors integrated therein or otherwise associated therewith.
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公开(公告)号：US10588575B2
公开(公告)日：2020-03-17
申请号：US15422329
申请日：2017-02-01
发明人： Rebecca K. Gottlieb , Ying Luo , Raghavendhar Gautham , Bradley Liang , Anirban Roy , Kenneth W. Cooper , Rajiv Shah , Barry Keenan
IPC分类号： A61B5/00 , A61M5/172 , A61B5/145 , A61B5/1495 , A61B5/1473
摘要： Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.
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公开(公告)号：US20180318549A1
公开(公告)日：2018-11-08
申请号：US15973465
申请日：2018-05-07
发明人： Chia-Hung Chiu , Hsifu Wang , Rebecca K. Gottlieb
CPC分类号： A61M25/0043 , A61B17/3415 , A61B2017/3454 , A61L29/06 , A61M5/142 , A61M5/14248 , A61M5/158 , A61M25/0009 , A61M25/065 , A61M39/02 , A61M39/08 , A61M2005/1585 , A61M2005/1587 , A61M2025/0059
摘要： A flexible, fluid flow tubing is configured to be kink resistant, and a medical device is configured with such kink resistant tubing. The tubing has a length L and a circular cross-section shape taken perpendicular to the length dimension. The tubing has an inside radius r and an outside radius R, wherein L/R≥34.8, and wherein R/r≥1.5. The tubing may be made of a polyether block amide (PEBA) or other thermoplastic elastomer (TPE). The tubing may be received in a channel of a hollow needle, wherein the needle is slideable in the axial dimension relative to the tubing, to selectively slide off of at least a portion of the tubing.
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