公开(公告)号：US20170316150A1

公开(公告)日：2017-11-02

申请号：US15517107

申请日：2015-10-09

Applicant: Sequenom, Inc.

Inventor： Cosmin DECIU ,  Chen ZHAO

IPC: G06F19/22

CPC classification number: G16B30/00 ,  C12Q1/6869 ,  C12Q2537/165

Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations that make use of nucleic acid fragments from circulating cell free nucleic acid. Also provided herein are methods for partitioning one or more genomic regions of a reference genome into a plurality of portions according to one or more features.

公开(公告)号：US20160319335A1

公开(公告)日：2016-11-03

申请号：US15149045

申请日：2016-05-06

Applicant: SEQUENOM, INC.

Inventor： Cosmin DECIU ,  Zeljiko DZAKULA ,  Mathias EHRICH ,  Sung Kyun KIM

IPC: C12Q1/68 ,  G06F19/18

CPC classification number: C12Q1/6827 ,  G06F19/18 ,  C12Q2537/16 ,  C12Q2537/165

Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US20160224724A1

公开(公告)日：2016-08-04

申请号：US14892782

申请日：2014-05-23

Applicant: SEQUENOM, INC.

Inventor： Chen ZHAO ,  Zeljko DZAKULA ,  Cosmin DECIU ,  Sung Kyun KIM ,  Amin R. MAZLOOM ,  Gregory HANNUM ,  Mathias EHRICH

IPC: G06F19/20

Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations that make use of decision analyses. The decision analyses sometimes include segmentation analyses and/or odds ratio analyses.

Abstract translation: 本文提供了利用决策分析进行遗传变异的非侵入式评估的方法，过程和装置。 决策分析有时包括分段分析和/或优势比分析。

公开(公告)号：US20160110497A1

公开(公告)日：2016-04-21

申请号：US14781987

申请日：2014-04-02

Applicant: SEQUENOM INC.

Inventor： Zeljko DZAKULA ,  Chen ZHAO ,  Cosmin DECIU

IPC: G06F19/18 ,  G06F19/22 ,  G06F19/24 ,  G06F17/18

CPC classification number: G16B20/00 ,  G06F17/18 ,  G16B30/00 ,  G16B40/00

Abstract: Provided herein are methods, processes, apparatuses and machines for non-invasive assessment of genetic variations.

Abstract translation: 本文提供了用于遗传变异的非侵入性评估的方法，过程，装置和机器。