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31.发明申请公开(公告)号：US20050080081A1
公开(公告)日：2005-04-14
申请号：US10470861
申请日：2002-01-28
申请人： Alexander Straub , Thomas Lampe , Josef Pernerstorfer , Elisabeth Perzborn , Jens Pohlmann , Susanne Rohrig , Karl-Heinz Schlemmer
发明人： Alexander Straub , Thomas Lampe , Josef Pernerstorfer , Elisabeth Perzborn , Jens Pohlmann , Susanne Rohrig , Karl-Heinz Schlemmer
IPC分类号： A61K31/422 , A61K31/5377 , A61P7/02 , A61P9/10 , A61P19/02 , A61P25/28 , A61P35/00 , C07D413/10 , C07D413/14 , C07D413/02 , A61K31/421 , A61K31/454 , A61K31/496
CPC分类号： C07D413/10 , C07D413/14
摘要： The invention relates to the field of blood coagulation, more particularly, to novel compounds of general formula (I), to a method for producing said compounds and to their use as active ingredients in medicaments for the prevention and/or the treatment of diseases.
摘要翻译： 本发明涉及血液凝固领域，更具体地说，涉及通式（I）的新型化合物，涉及用于制备所述化合物的方法及其作为用于预防和/或治疗疾病的药物中的活性成分的用途。
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公开(公告)号：US08530505B2
公开(公告)日：2013-09-10
申请号：US13360107
申请日：2012-01-27
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/42 , C07D409/14
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
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公开(公告)号：US20130005701A1
公开(公告)日：2013-01-03
申请号：US13360107
申请日：2012-01-27
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/422 , A61K31/5377 , C07D417/14 , A61K31/541 , C07D495/04 , C12N5/078 , A61K31/428 , A61K31/496 , A61K31/444 , A61K31/454 , A61K31/538 , A61K31/5383 , C07D413/14 , A61K31/4365
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
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34.发明授权公开(公告)号：US08129378B2
公开(公告)日：2012-03-06
申请号：US12494879
申请日：2009-06-30
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/5377 , A61K31/42 , C07D409/14
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
摘要翻译： 本发明涉及血液凝固领域。 描述了通式（I）的新型恶唑烷酮衍生物的制备及其作为用于预防和/或治疗病症的药物活性化合物的用途。
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35.发明授权公开(公告)号：US07576111B2
公开(公告)日：2009-08-18
申请号：US11932082
申请日：2007-10-31
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/42 , C07D409/14
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
摘要翻译： 本发明涉及血液凝固领域。 描述了通式（I）的新型恶唑烷酮衍生物的制备及其作为用于预防和/或治疗病症的药物活性化合物的用途。
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公开(公告)号：US20080090815A1
公开(公告)日：2008-04-17
申请号：US11932082
申请日：2007-10-31
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/541 , A61K31/421 , A61K31/4453 , A61P9/10 , C07D401/14 , C07D417/14 , C07D413/14 , C07D263/02 , A61P9/00 , A61K31/5355
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
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公开(公告)号：US20050004207A1
公开(公告)日：2005-01-06
申请号：US10484369
申请日：2002-07-03
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Stephan Jordan , Elisabeth Perzborn , Karl-Heinz Schlemmer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Stephan Jordan , Elisabeth Perzborn , Karl-Heinz Schlemmer
IPC分类号： C07D473/00 , A61K31/4025 , A61K31/4035 , A61K31/4155 , A61K31/4178 , A61K31/4184 , A61K31/422 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/52 , A61K31/5377 , A61P7/02 , A61P9/00 , A61P9/08 , A61P9/10 , A61P11/00 , A61P19/02 , A61P25/28 , A61P35/00 , C07D209/46 , C07D209/48 , C07D213/81 , C07D409/12 , C07D409/14 , C07D413/14 , C07D471/04 , C07D471/14 , C07D521/00 , A61K31/4015 , C07D207/40
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D409/12 , C07D409/14 , C07D471/14
摘要： The invention relates to the field of blood clotting, to novel compounds of formula (I), to a method for their production and to the use of these compounds as active ingredients in medicaments for preventing and/or treating diseases. The compounds are factor Xa inhibitors.
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38.发明申请Methods For The Prophylaxis And/or Treatment Of Thromboembolic Disorders By Combination Therapy With Substituted Oxazolidinones 审中-公开通过与取代的恶唑烷酮组合治疗预防和/或治疗血栓栓塞障碍的方法公开(公告)号：US20100267685A1
公开(公告)日：2010-10-21
申请号：US12766365
申请日：2010-04-23
申请人： Alexander Straub , Thomas Lampe , Josef Pernerstorfer , Elisabeth Perzborn , Jens Pohlmann , Susanne Röhrig , Karl-Heinz Schlemmer
发明人： Alexander Straub , Thomas Lampe , Josef Pernerstorfer , Elisabeth Perzborn , Jens Pohlmann , Susanne Röhrig , Karl-Heinz Schlemmer
IPC分类号： A61K31/397 , A61K31/5377 , A61K31/541 , A61K31/4365 , A61K31/428 , A61K31/496 , A61K31/444 , A61K31/454 , A61K31/422 , A61K31/423 , A61K31/538 , A61K31/4439 , A61K31/5355 , A61K31/427 , A61P9/08 , A61P7/02 , A61P9/10 , A61P3/06 , A61P9/00 , A61P9/04 , A61K31/5365
CPC分类号： A61K31/422 , A61K31/421 , A61K31/5377 , A61K45/06 , A61K2300/00
摘要： The invention relates to combinations of A) oxazolidinones of formula (I) and B) other active ingredients, to a method for producing said combinations and to the use thereof as medicaments, in particular for the treatment and/or prophylaxis of thrombo-embolic diseases.
摘要翻译： 本发明涉及式（I）的A）恶唑烷酮和B）其它活性成分的组合，用于制备所述组合的方法及其作为药物的用途，特别是用于治疗和/或预防血栓栓塞性疾病 。
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39.发明申请公开(公告)号：US20100137274A1
公开(公告)日：2010-06-03
申请号：US12494879
申请日：2009-06-30
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/422 , C07D413/14 , C07D417/14 , C07D495/04 , C07D498/04 , C12N5/00 , A61K31/5377 , A61K31/541 , A61K31/4365 , A61K31/428 , A61K31/496 , A61K31/444 , A61K31/4545 , A61K31/423 , A61K31/538
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
摘要翻译： 本发明涉及血液凝固领域。 描述了通式（I）的新型恶唑烷酮衍生物的制备及其作为用于预防和/或治疗病症的药物活性化合物的用途。
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公开(公告)号：US07585860B2
公开(公告)日：2009-09-08
申请号：US12027553
申请日：2008-02-07
申请人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Rohrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstorfer
IPC分类号： A61K31/5377 , C07D409/14
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
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