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公开(公告)号:US20050065160A1
公开(公告)日:2005-03-24
申请号:US10832109
申请日:2004-04-26
申请人: Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Rudolf Schohe-Loop , Frank Sussmeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jorg Keldenich , Dieter Lang , Peter Nell
发明人: Tobias Wunberg , Judith Baumeister , Ulrich Betz , Mario Jeske , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Rudolf Schohe-Loop , Frank Sussmeier , Holger Zimmermann , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Jorg Keldenich , Dieter Lang , Peter Nell
IPC分类号: A61P31/22 , C07D239/84 , A61K31/517 , C07D43/04
CPC分类号: C07D239/84
摘要: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
摘要翻译: 本发明涉及取代的二氢喹唑啉及其制备方法,也涉及其用于制备用于治疗和/或预防疾病,特别是用作抗病毒剂,特别是针对巨细胞病毒的药物的用途。
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公开(公告)号:US20050059658A1
公开(公告)日:2005-03-17
申请号:US10482520
申请日:2002-06-17
申请人: Tobias Wunberg , Ulrich Betz , Sabine Hallenberger , Gerald Kleymann , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Franz Zumpe , Marcus Bauser , Wolfgang Bender , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Axel Jensen , Jorg Keldenich , Holger Zimmermann
发明人: Tobias Wunberg , Ulrich Betz , Sabine Hallenberger , Gerald Kleymann , Thomas Lampe , Susanne Nikolic , Jurgen Reefschlager , Franz Zumpe , Marcus Bauser , Wolfgang Bender , Rolf Grosser , Kerstin Henninger , Guy Hewlett , Axel Jensen , Jorg Keldenich , Holger Zimmermann
IPC分类号: A61K31/50 , A61K31/501 , A61P31/12 , C07D237/04 , C07D237/32 , C07D417/12
CPC分类号: C07D417/12 , C07D237/04 , C07D237/32
摘要: The invention relates to novel compounds, to a method for the production of said compounds and to the use thereof as medicaments, more particularly as antiviral agents, especially against cytomegalovirus.
摘要翻译: 本发明涉及新化合物,所述化合物的制备方法及其作为药物的用途,更特别地涉及抗病毒剂,特别是抗巨细胞病毒。
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33.3-'Hydroxy-(-4-trifluoromethylphenyl)-methyl-7-spirocyclobutyl-5,6,7 8-tetrahydroquinolin-5-ol derivatives and the use of the same as cholesterol ester transfer protein (cetp) inhibitors 审中-公开
标题翻译: 3-羟基 - ( - 4-三氟甲基苯基) - 甲基-7-螺环丁基-5,6,7,8-四氢喹啉-5-醇衍生物及其与胆固醇酯转移蛋白(cetp)抑制剂的用途公开(公告)号:US20050043341A1
公开(公告)日:2005-02-24
申请号:US10491465
申请日:2002-09-18
申请人: Heike Gielen , Siegfried Goldmann , Jorg Keldenich , Holger Paulsen , Carsten Schmeck , Stephan Siegel , Hilmar Bischoff , Martin Raabe , Delf Schmidt , Christiane Faeste
发明人: Heike Gielen , Siegfried Goldmann , Jorg Keldenich , Holger Paulsen , Carsten Schmeck , Stephan Siegel , Hilmar Bischoff , Martin Raabe , Delf Schmidt , Christiane Faeste
IPC分类号: C07D215/20 , A61K31/47 , A61K31/4709 , A61P3/04 , A61P3/06 , A61P9/00 , A61P9/10 , A61P25/28 , A61P43/00 , C07D221/20 , C07D409/04 , A61K31/4747
CPC分类号: C07D221/20 , C07D409/04
摘要: The application relates to substituted tetrahydroquinoline derivatives, processes for their preparation and their use in medicaments.
摘要翻译: 本申请涉及取代的四氢喹啉衍生物,其制备方法及其在药物中的用途。
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