-
31.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 193P1E1B USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白193P1E1B被用于治疗和检测癌症公开(公告)号：US20090249502A1
公开(公告)日：2009-10-01
申请号：US12206895
申请日：2008-09-09
申请人： Arthur B. Raitano , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Wangmao Ge , Aya Jakobovits
发明人： Arthur B. Raitano , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Wangmao Ge , Aya Jakobovits
IPC分类号： A01K67/027 , C07K16/18 , C12N5/06
CPC分类号： C07K16/30 , A61K2039/505 , C07K2317/34 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , Y02A50/466
摘要： A novel gene (designated 193P1E1B) and its encoded protein, and variants thereof, are described wherein 193P1E1B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 193P1E1B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 193P1E1B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 191P1E1B can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（命名为193P1E1B）及其编码的蛋白质及其变体，其中193P1E1B在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，193P1E1B提供诊断，预后， 癌症的预防和/或治疗靶标。 193P1E1B基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与191P1E1B反应的抗体或T细胞可用于主动或被动免疫。
-
32.发明授权Nucleic acid and corresponding protein entitled 125P5C8 useful in treatment and detection of cancer 失效核酸和相应的蛋白质125P5C8可用于治疗和检测癌症公开(公告)号：US07488479B2
公开(公告)日：2009-02-10
申请号：US10099460
申请日：2002-03-13
申请人： Mary Faris , Pia M. Challita-Eid , Rene S. Hubert , Daniel E. H. Afar , Arthur B. Raitano , Wangmao Ge , Robert Kendall Morrison , Karen Jane Meyrick Morrison , Aya Jakobovits
发明人： Mary Faris , Pia M. Challita-Eid , Rene S. Hubert , Daniel E. H. Afar , Arthur B. Raitano , Wangmao Ge , Robert Kendall Morrison , Karen Jane Meyrick Morrison , Aya Jakobovits
IPC分类号： A61K39/00
CPC分类号： C07K14/47 , A61K38/00 , A61K39/00 , Y02A50/466
摘要： A novel gene (designated 125P5C8) and its encoded protein, and variants thereof, are described wherein 125P5C8 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 125P5C8 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 125P5C8 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 125P5C8 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为125P5C8）及其编码的蛋白及其变体，其中125P5C8在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，125P5C8提供诊断，预后， 癌症的预防和/或治疗靶标。 125P5C8基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与125P5C8反应的抗体或T细胞可用于主动或被动免疫。
-
公开(公告)号：US07361338B2
公开(公告)日：2008-04-22
申请号：US10147368
申请日：2002-05-15
申请人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
发明人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
IPC分类号： A61K39/395
CPC分类号： G01N33/68 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K14/47 , C07K14/705 , C07K16/28 , C07K2317/34 , G01N33/5017 , G01N33/57434
摘要： A novel gene (designated 101P3A11 or PHOR-1) and its encoded protein, and variants thereof, are described wherein 101P3A11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 101P3A11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 101P3A11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 101P3A11 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为101P3A11或PHOR-1）及其编码蛋白及其变体，其中101P3A11在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，101P3A11提供 诊断，预后，预防和/或治疗靶标。 101P3A11基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与101P3A11反应的抗体或T细胞可用于主动或被动免疫。
-
公开(公告)号：US08236510B2
公开(公告)日：2012-08-07
申请号：US12842971
申请日：2010-07-23
申请人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
发明人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
IPC分类号： G01N33/53
CPC分类号： G01N33/68 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K14/47 , C07K14/705 , C07K16/28 , C07K2317/34 , G01N33/5017 , G01N33/57434
摘要： A novel gene (designated 101P3A11 or PHOR-1) and its encoded protein, and variants thereof, are described wherein 101P3A11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 101P3A11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 101P3A11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 101P3A11 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为101P3A11或PHOR-1）及其编码蛋白及其变体，其中101P3A11在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，101P3A11提供 诊断，预后，预防和/或治疗靶标。 101P3A11基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与101P3A11反应的抗体或T细胞可用于主动或被动免疫。
-
35.发明授权Nucleic acid and corresponding protein entitled 85P1B3 useful in treatment and detection of cancer 失效核酸和相应的标题为85P1B3的蛋白质可用于治疗和检测癌症公开(公告)号：US08173381B2
公开(公告)日：2012-05-08
申请号：US12359203
申请日：2009-01-23
申请人： Arthur B. Raitano , Mary Faris , Rene S. Hubert , Daniel Afar , Wangmao Ge , Pia M. Challita-Eid , Aya Jakobovits
发明人： Arthur B. Raitano , Mary Faris , Rene S. Hubert , Daniel Afar , Wangmao Ge , Pia M. Challita-Eid , Aya Jakobovits
IPC分类号： G01N33/574
CPC分类号： C07K14/47
摘要： A novel gene (designated 85P1B3) and its encoded protein are described. While 85P1B3 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 85P1B3 provides a diagnostic and/or therapeutic target for cancers. The 85P1B3 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
摘要翻译： 描述了一种新型基因（命名为85P1B3）及其编码的蛋白质。 虽然85P1B3在正常成人组织中表现出组织特异性表达，但是在多种癌症中异常表达，如表1所示。因此，85P1B3为癌症提供了诊断和/或治疗靶点。 85P1B3基因或其片段或其编码的蛋白质或其片段可用于引发免疫应答。
-
36.发明授权Nucleic acids and corresponding proteins entitled 202P5A5 useful in treatment and detection of cancer 失效题为202P5A5的核酸和相应的蛋白质可用于治疗和检测癌症公开(公告)号：US08057996B2
公开(公告)日：2011-11-15
申请号：US11548626
申请日：2006-10-11
IPC分类号： C12Q1/68
CPC分类号： C12N5/0693 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K47/6851 , A61K2039/505 , C07K14/435 , C07K14/47 , C07K2319/00 , G01N33/57484 , Y02A50/466
摘要： A novel gene 202P5A5 and its encoded protein, and variants thereof, are described wherein 202P5A5 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 202P5A5 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 202P5A5 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 202P5A5 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因202P5A5及其编码的蛋白质及其变体，其中202P5A5在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，202P5A5提供诊断，预后，预防和/ 或癌症的治疗靶标。 202P5A5基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与202P5A5反应的抗体或T细胞可用于主动或被动免疫。
-
37.发明授权Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer 失效核酸和相应的蛋白质121P1F1可用于治疗和检测癌症公开(公告)号：US08039603B2
公开(公告)日：2011-10-18
申请号：US12473056
申请日：2009-05-27
申请人： Pia M. Challita-Eid , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
发明人： Pia M. Challita-Eid , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
IPC分类号： C07H21/02
CPC分类号： C07K14/47 , A61K38/00 , A61K39/00 , A61K2039/505 , C07K16/30 , C07K2317/34 , G01N33/574 , Y02A50/466
摘要： A novel gene (designated 121P1F1) and its encoded protein, and variants thereof, are described wherein 121P1F1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 121P1F1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 121P1F1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 121P1F1 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为121P1F1）及其编码的蛋白质及其变体，其中121P1F1在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，121P1F1提供诊断，预后， 癌症的预防和/或治疗靶标。 121P1F1基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与121P1F1反应的抗体或T细胞可用于主动或被动免疫。
-
公开(公告)号：US08003100B2
公开(公告)日：2011-08-23
申请号：US12785360
申请日：2010-05-21
申请人： Arthur B. Raitano , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Arthur B. Raitano , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： A61K39/395 , A61K39/44
CPC分类号： C07K16/30 , A61K39/395 , A61K2039/505 , C07K14/47 , C07K2317/34 , A61K2300/00
摘要： A novel gene (designated 238P1B2) and its encoded protein, and variants thereof, are described wherein 238P1B2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 238P1B2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 238P1B2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 238P1B2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（命名为238P1B2）及其编码的蛋白及其变体，其中238P1B2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，238P1B2提供诊断，预后， 癌症的预防和/或治疗靶标。 238P1B2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与238P1B2反应的抗体或T细胞可用于主动或被动免疫。
-
39.发明授权Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer 有权核酸和相应的标题为161P2F10B的蛋白质可用于治疗和检测癌症公开(公告)号：US07977062B2
公开(公告)日：2011-07-12
申请号：US12641261
申请日：2009-12-17
申请人： Aya Jakobovits , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
发明人： Aya Jakobovits , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
IPC分类号： G01N33/574 , G01N33/53
CPC分类号： C07K16/30 , A61K31/7088 , A61K39/00 , A61K51/1045 , A61K2039/505 , C07K14/47 , C07K16/18 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3061 , C07K16/3069 , C07K16/40 , C07K2317/20 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2319/30 , C12N9/16 , C12Q1/6886 , C12Q2600/158 , G01N33/57492 , Y02A50/466
摘要： A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.
摘要翻译： 描述了新颖的基因0161P2F10B（也称为161P2F10B）及其编码的蛋白质及其变体，其中161P2F10B在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，161P2F10B提供了诊断， 癌症的预后，预防和/或治疗靶标。 161P2F10B基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与161P2F10B反应的抗体或T细胞可用于主动或被动免疫。
-
40.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 162P1E6 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白162P1E6用于治疗和检测癌症公开(公告)号：US20110165148A1
公开(公告)日：2011-07-07
申请号：US13043221
申请日：2011-03-08
申请人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： A61K39/395 , C07K14/00 , C07K16/00 , C12N5/12 , C12N15/63 , A61K39/00 , G01N33/48 , G01N33/53 , G01N33/574 , A61P35/00 , A61P37/04
CPC分类号： C07K14/4748 , A61K39/00 , Y02A50/466 , Y10T436/143333
摘要： A novel gene (designated 162P1E6) and its encoded protein, and variants thereof, are described wherein 162P1E6 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 162P1E6 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 162P1E6 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 162P1E6 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（命名为162P1E6）及其编码的蛋白质及其变体，其中162P1E6在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，162P1E6提供诊断，预后， 癌症的预防和/或治疗靶标。 162P1E6基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与162P1E6反应的抗体或T细胞可用于主动或被动免疫。
-
-
-
-
-
-
-
-
-
搜索结果
155 条记录 (耗时 0.111 秒)
