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51 条记录 (耗时 0.062 秒)

    Deformed shank fastener
    31.
    发明授权
    Deformed shank fastener 有权
    变形的柄紧固件

    公开(公告)号：US07819614B2

    公开(公告)日：2010-10-26

    申请号：US12138180

    申请日：2008-06-12

    申请人： Anthony M. Versino ,  Kenneth R. Levey ,  Jeffrey L. Trzaskus ,  Lawrence S. Shelton ,  Donald E. Bergstrom

    发明人： Anthony M. Versino ,  Kenneth R. Levey ,  Jeffrey L. Trzaskus ,  Lawrence S. Shelton ,  Donald E. Bergstrom

    IPC分类号： F16B15/08

    CPC分类号： F16B15/06

    摘要： A nail has a head, a penetrating tip and a shank extending from the head to the penetrating tip. The shank has a circumference and a longitudinal axis. A plurality of rows of deformations formed as teeth are formed in the shank extending outwardly of the shank. The rows are formed in a spiral pattern along the length of the shank from about the head to about the penetrating tip. The rows of teeth are formed parallel to one another and formed at an angle of at least 50 degrees relative to a cross-sectional plane perpendicular to a longitudinal axis of the nail.

    摘要翻译： 指甲具有头部，穿透尖端和从头部延伸至穿透尖端的柄部。 柄具有圆周和纵向轴线。 形成为齿的多排变形形成在柄上延伸到柄的外侧。 这些排沿着柄的长度从螺旋形状形成为从头部到穿透尖端。 齿排彼此平行地形成，并且相对于垂直于钉的纵向轴线的横截面为至少50度的角度形成。

    DEFORMED SHANK FASTENER
    32.
    发明申请
    DEFORMED SHANK FASTENER 有权
    变形山紧固件

    公开(公告)号：US20090155021A1

    公开(公告)日：2009-06-18

    申请号：US12138180

    申请日：2008-06-12

    申请人： Anthony M. Versino ,  Kenneth R. Levey ,  Jeffrey L. Trzaskus ,  Lawrence S. Shelton ,  Donald E. Bergstrom

    发明人： Anthony M. Versino ,  Kenneth R. Levey ,  Jeffrey L. Trzaskus ,  Lawrence S. Shelton ,  Donald E. Bergstrom

    IPC分类号： F16B15/00

    CPC分类号： F16B15/06

    摘要： A nail has a head, a penetrating tip and a shank extending from the head to the penetrating tip. The shank has a circumference and a longitudinal axis. A plurality of rows of deformations formed as teeth are formed in the shank extending outwardly of the shank. The rows are formed in a spiral pattern along the length of the shank from about the head to about the penetrating tip. The rows of teeth are formed parallel to one another and formed at an angle of at least 50 degrees relative to a cross-sectional plane perpendicular to a longitudinal axis of the nail.

    摘要翻译： 指甲具有头部，穿透尖端和从头部延伸至穿透尖端的柄部。 柄具有圆周和纵向轴线。 形成为齿的多排变形形成在柄上延伸到柄的外侧。 这些排沿着柄的长度从螺旋形状形成为从头部到穿透尖端。 齿排彼此平行地形成，并且相对于垂直于钉的纵向轴线的横截面为至少50度的角度形成。

    MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME
    33.
    发明申请
    MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME 审中-公开
    可以在水溶液中二维分离的单体及其使用方法

    公开(公告)号：US20140194383A1

    公开(公告)日：2014-07-10

    申请号：US14110056

    申请日：2012-04-09

    申请人： Francis Barany ,  Maneesh Pingle ,  Donald E. Bergstrom ,  Sarah F. Giardina ,  Lee Daniel Arnold

    发明人： Francis Barany ,  Maneesh Pingle ,  Donald E. Bergstrom ,  Sarah F. Giardina ,  Lee Daniel Arnold

    IPC分类号： C07D211/26 ,  C07F5/04

    CPC分类号： C07D211/26 ,  C07D405/06 ,  C07D409/06 ,  C07D491/107 ,  C07F5/025 ,  C07F5/04

    摘要： Described herein are monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.

    摘要翻译： 本文描述的是当在水性介质中与一种，两种，三种或更多种其它单体接触时，能够形成生物有用的多聚体的单体。 在一个方面，这样的单体可以能够在水性介质（例如体内）中结合另一单体以形成多聚体（例如二聚体）。 考虑的单体可以包括配体部分，连接体元件和连接配体部分和连接体元件的连接器元件。 在水性介质中，这样预期的单体可以经由每个连接体元件连接在一起，因此可以基本上同时调节一种或多种生物分子，例如调节蛋白质上或不同蛋白质上的两个或多个结合结构域。

    SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME
    34.
    发明申请
    SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME 审中-公开
    可在水溶液中多元化的SILYL单体及其使用方法

    公开(公告)号：US20140163229A1

    公开(公告)日：2014-06-12

    申请号：US14110060

    申请日：2012-04-09

    申请人： Francis Barany ,  Maneesh Pingle ,  Donald E. Bergstrom ,  Sarah F. Giardina ,  Lee Daniel Arnold

    发明人： Francis Barany ,  Maneesh Pingle ,  Donald E. Bergstrom ,  Sarah F. Giardina ,  Lee Daniel Arnold

    IPC分类号： C07F7/10

    CPC分类号： A61K31/695 ,  A61K47/55 ,  C07F7/10

    摘要： Described herein are silyl monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. Such multimer forming associations of monomers may be promoted by the proximal binding of the monomers to their target biomolecule(s). In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.

    摘要翻译： 本文描述的是当在水性介质中与一种，两种，三种或更多种其它单体接触时能够形成生物学上有用的多聚体的甲硅烷基单体。 单体的这种多聚体形成关联可以通过单体与其目标生物分子的近端结合来促进。 在一个方面，这样的单体可以能够在水性介质（例如体内）中结合另一单体以形成多聚体（例如二聚体）。 考虑的单体可以包括配体部分，连接体元件和连接配体部分和连接体元件的连接器元件。 在水性介质中，这样预期的单体可以经由每个连接体元件连接在一起，因此可以基本上同时调节一种或多种生物分子，例如调节蛋白质上或不同蛋白质上的两个或多个结合结构域。

    Palladium mediated reaction of organic disulfides with mercurated nucleic acid components
    35.
    发明授权
    Palladium mediated reaction of organic disulfides with mercurated nucleic acid components 失效
    钯介导的有机二硫化物与汞化核酸组分的反应

    公开(公告)号：US4983727A

    公开(公告)日：1991-01-08

    申请号：US179751

    申请日：1988-04-11

    申请人： Donald E. Bergstrom ,  Jeffrey A. Jenson

    发明人： Donald E. Bergstrom ,  Jeffrey A. Jenson

    IPC分类号： C07H19/06 ,  C07H19/16

    CPC分类号： C07H19/06 ,  C07H19/16

    摘要： A method of preparing C-5 substituted nucleotides by reacting a C-5 posit mercurated nucleoside with an alkyl or aryl disulfide in the presence of palladium(II) ion. The resulting new method for attaching linker arms to nucleic acids (DNA,RNA) provides a wide ranging reaction far more useful than those heretofore developed, and allows preparation of modified components with linking reactive functionality that allows usefulness as probes, therapeutics, and for DNA sequencing.

    摘要翻译： 一种通过在钯（II）离子存在下使C-5位甘氨酸核苷与烷基或芳基二硫化物反应制备C-5取代核苷酸的方法。 用于将连接臂连接到核酸（DNA，RNA）的所得新方法提供了比迄今开发的更广泛的反应，并且允许制备具有连接反应性官能团的改性组分，其允许作为探针，治疗剂和DNA的有用性 测序

    Apparatus for making debris-free nail collation
    39.
    发明授权
    Apparatus for making debris-free nail collation 有权
    无碎屑指甲整理的装置

    公开(公告)号：US08251686B1

    公开(公告)日：2012-08-28

    申请号：US12627866

    申请日：2009-11-30

    申请人： Isaac H. Heskel ,  Lawrence S. Shelton ,  Donald E. Bergstrom ,  Michael J. Christensen ,  Algis P. Suopys ,  Eldrige J. Presnell ,  Joseph J. Righter, Jr. ,  Richard W. Mrozik, Jr.

    发明人： Isaac H. Heskel ,  Lawrence S. Shelton ,  Donald E. Bergstrom ,  Michael J. Christensen ,  Algis P. Suopys ,  Eldrige J. Presnell ,  Joseph J. Righter, Jr. ,  Richard W. Mrozik, Jr.

    IPC分类号： B29C70/84

    CPC分类号： B29C70/74 ,  B29B13/02 ,  B29C35/045 ,  B29C2035/0811 ,  B29C2035/1616 ,  B29C2035/1691

    摘要： An apparatus for forming a plastic molded collated fastener assembly includes a conveyor for carrying a plurality of fasteners in a horizontal plane defining an upper surface and a lower surface, a preheater for preheating the plurality of nails and a plastic collation molding station. The molding station includes injection nozzles for applying molten plastic to the upper surface of the fasteners and to the lower surface of the fasteners. The station further includes forming wheels including a holding section to, in cooperation with the conveyor, secure the fasteners. The wheels include a forming section to mold the molten plastic to the fasteners to form a collation having a collar encircling the fasteners' shanks and a connecting portion extending between the collars. The apparatus includes at least one cooling spray nozzle to spray a cooling vapor onto the fasteners and collations and at least one cooling spray nozzle to spray a cooling vapor onto the forming wheels. An air chiller further cools the collations.

    摘要翻译： 一种用于形成塑料成型的整理的紧固件组件的装置包括用于在限定上表面和下表面的水平平面中承载多个紧固件的输送机，用于预热多个钉子的预热器和塑料整理成型台。 成型站包括用于将熔融塑料施加到紧固件的上表面和紧固件的下表面的注射嘴。 车站还包括形成轮，其包括保持部分，以与输送机协作，固定紧固件。 车轮包括成形部分，用于将熔融塑料模制成紧固件以形成具有环绕紧固件柄部的轴环和在轴环之间延伸的连接部分的对准。 该装置包括至少一个冷却喷嘴，用于将冷却蒸汽喷射到紧固件和排齐物上，以及至少一个冷却喷嘴以将冷却蒸汽喷射到成型轮上。 空气冷却器进一步冷却排序。

    DEBRIS-FREE PLASTIC COLLATING STRIP FOR NAILS
    40.
    发明申请
    DEBRIS-FREE PLASTIC COLLATING STRIP FOR NAILS 有权
    用于钉子的无破碎塑料收缩条

    公开(公告)号：US20080282529A1

    公开(公告)日：2008-11-20

    申请号：US12176722

    申请日：2008-07-21

    申请人： Lawrence S. Shelton ,  Paul J. Storiz ,  Michael Starozhitzky ,  Algis P. Suopys ,  Donald E. Bergstrom

    发明人： Lawrence S. Shelton ,  Paul J. Storiz ,  Michael Starozhitzky ,  Algis P. Suopys ,  Donald E. Bergstrom

    IPC分类号： B22D11/128

    CPC分类号： F16B15/08 ,  Y10T29/49982

    摘要： A fastener assembly is configured for use in an associated fastener driving tool for driving a fastener from the assembly into an associated substrate. The assembly includes a row of fasteners, each having a shank, arranged substantially parallel to each other. A collation system is formed from a plastic material that is molded onto and adhered to the fasteners. The plastic material is molded to define a collar portion substantially encircling the fastener shank and a connecting portion extending between and connecting adjacent collar potions. The plastic material is formulated from an adhesive polymer. When the fastener is driven from the driving tool, the collar portion remains adhered to the fastener such that the collar portion penetrates the substrate with the fastener.

    摘要翻译： 紧固件组件被构造成用于相关联的紧固件驱动工具中，用于将紧固件从组件驱动到相关联的基底中。 组件包括一排紧固件，每排紧固件具有基本上彼此平行布置的柄部。 对照系统由塑料材料形成，该塑料材料被模制并粘附到紧固件上。 塑料材料被模制以限定基本上环绕紧固件柄的套环部分和在相邻套环部分之间延伸并连接相邻套环部分的连接部分。 塑料材料由粘合剂聚合物制成。 当紧固件从驱动工具驱动时，套环部分保持粘附到紧固件上，使得套环部分用紧固件穿透衬底。