公开(公告)号：US10676501B2

公开(公告)日：2020-06-09

申请号：US13554930

申请日：2012-07-20

Applicant: Paul B. Savage

Inventor： Paul B. Savage

IPC: A61L27/14 ,  C07J41/00 ,  A61L27/52 ,  A61L27/54 ,  A61L31/14 ,  A61L31/16 ,  A61L27/34 ,  A61L29/08 ,  A61L29/14 ,  A61L29/16 ,  A61L31/10 ,  C07C211/00 ,  A61L27/18 ,  A61L29/04 ,  A61L31/04

Abstract: A hydrogel polymer includes a ceragenin compound. The ceragenin compound has a hydrophobicity/hydrophilicity that produces a release rate in a range of 0.1-100 μg/ml for at least 3 days.

公开(公告)号：US10657219B2

公开(公告)日：2020-05-19

申请号：US15960282

申请日：2018-04-23

Applicant: Brigham Young University

Inventor： Kelly Eric Bowman ,  Spencer Carter ,  Scott Jackson ,  Jessica Collyer ,  Scott Christensen ,  Abigail Christensen ,  Joanna Hugo ,  Jacob Wardell

IPC: G06F17/50 ,  G06Q10/10 ,  G06T19/20 ,  H04L29/08

Abstract: A method, executed by at least one processor, may include executing a first CAx application configured to enable a first user to edit a first 3D proprietary model comprising a plurality of features for a part that is to be manufactured, wherein the first 3D proprietary model is encoded in a first CAx format. The method may also include, executing a synchronization plugin module for the first CAx application and detecting, with the synchronization plugin module, a request by the first user to generate a first 2D manufacturing drawing and model corresponding to a selected view of the part that is to be manufactured. The method may also include initiating generation of a 2D collaborative model corresponding to the first 2D manufacturing model and initiating storage of the 2D collaborative model on a collaborative data store. A corresponding system and computer readable medium are also disclosed herein.

公开(公告)号：US20200078425A1

公开(公告)日：2020-03-12

申请号：US16493975

申请日：2018-03-14

Applicant: Brigham Young University

Inventor： Laura Clarke Bridgewater ,  Gongze Zhao

IPC: A61K35/76 ,  A61P3/04 ,  A61P29/00

Abstract: The present disclosure as disclosed in various embodiments relates to methods and compositions of treating obesity, inflammation, or obesity-associated metabolic disorders with bacteriophages and processes for preparing the compositions.

公开(公告)号：US10581893B2

公开(公告)日：2020-03-03

申请号：US15833693

申请日：2017-12-06

Applicant: BRIGHAM YOUNG UNIVERSITY ,  Washington State University

Inventor： Sean Warnick ,  Sandip Roy

IPC: H04L29/06 ,  G06F7/08

Abstract: Techniques of preventing sabotage attacks in cyber-physical systems involve automatically identifying links between nodes of a graph representing cyber-physical systems as vulnerable to sabotage attacks according to a vulnerability metric for each link. The vulnerability metric used depends on the particular sabotage attack used to determine the vulnerable links. Once a computer configured to design cyber-physical systems based on vulnerability to sabotage attacks receives data representing the graph, the computer enumerates the possible links between nodes of the graph along which a sabotage attack may be performed. For each of those links, the computer computes the vulnerability metric. The computer then ranks the links according to respective values of the vulnerability metric. Based on the ranking, a designer may then perform a mitigation analysis that results in changes to the graph to reduce the vulnerability at each node accessible to a malicious actor.

公开(公告)号：US10568893B2

公开(公告)日：2020-02-25

申请号：US14873013

申请日：2015-10-01

Applicant: Paul B. Savage ,  Carl Genberg

Inventor： Paul B. Savage ,  Carl Genberg

IPC: A61K31/575 ,  A61K45/06 ,  C07J41/00

Abstract: Methods of treating, reducing, or preventing a disease or symptom relating to a disease such as oral mucositis, gingivitis, periodontitis, gastric mucositis, inflammatory fibrosis, gastritis, colitis, ileitis, Crohn's disease, chronic inflammatory intestinal disease, inflammatory bowel syndrome, chronic inflammatory bowel disease, celiac disease, ulcerative colitis, a gastric ulcer, a peptic ulcer, a buccal ulcer, a nasopharyngeal ulcer, an esophageal ulcer, a duodenal ulcer, a gastrointestinal ulcer, an autoimmune disorder, inflammation associated with cancer, cancer treatment, or radiation, and/or pain that include: identifying a patient in need of treatment; and administering a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA), or a pharmaceutically acceptable salt thereof. Kits comprising such compositions and instructions on such methods are also contemplated herein.

公开(公告)号：US10430432B2

公开(公告)日：2019-10-01

申请号：US14738667

申请日：2015-06-12

Applicant: Brigham Young University

Inventor： Kelly Eric Bowman ,  Joshua Coburn ,  Ammon Hepworth ,  Charles Gregory Jensen ,  Jordan Johnson

IPC: G06F16/25 ,  H04L29/08 ,  G06Q10/10 ,  G06Q10/08

Abstract: An apparatus, method, and program product are disclosed for collaborative product lifecycle management. One apparatus includes a data processing module that receives product lifecycle management (“PLM”) data from multiple client applications in a collaborative environment. The PLM data may be in a client specific format. The apparatus includes a subscription module that receives one or more subscription requests from each client application. Moreover, the apparatus includes a conversion module that converts the PLM data from the client specific format to a generic format. The apparatus includes a storage module that stores the generic format of the PLM data. The conversion module may convert subscription data from the generic format to the client specific format. The subscription data may correspond to the PLM data stored in the generic format. The subscription module may provide the subscription data to the multiple client applications based on the one or more subscription requests.

公开(公告)号：US10402518B2

公开(公告)日：2019-09-03

申请号：US14139613

申请日：2013-12-23

Applicant: Brigham Young University

Inventor： Larissa Cannon ,  Charles Gregory Jensen ,  Thomas Trevor Nysetvold

IPC: G06F17/10 ,  G06F17/50

Abstract: A method for collaborative analysis pre-processing of electronic models of engineering objects includes assigning a first user to de-feature a model of an engineering object during a first session to provide a de-featured model of an engineering object, assigning a second user to conduct other FEA pre-processing operations on the model of the engineering object during a second session, and applying the other FEA pre-processing operations for the model of the engineering object to the de-featured model of the engineering object. Example of other FEA pre-processing operations include applying a material definition to a geometry, pre-meshing a geometry, initiating automated meshing of a geometry, validating automated meshing of a geometry, editing a mesh for a geometry, manually meshing a geometry, and defining one or more boundary conditions for a geometry. The second session and the first session may be conducted concurrently. A corresponding system and apparatus are also disclosed herein.

公开(公告)号：US20190212518A1

公开(公告)日：2019-07-11

申请号：US16353787

申请日：2019-03-14

Applicant: Brigham Young University

Inventor： Daniel Smalley

IPC: G02B7/00 ,  G02B26/10 ,  G02B26/12

CPC classification number: G02B7/005 ,  G02B26/105 ,  G02B26/127

Abstract: A method and system are disclosed for using circular symmetry to eliminate the angle limitations of an optical axis in a scanned aperture holography system. A Room-sized Holography System may be a scanned aperture holographic video display and may comprise a rotating platform, a telescope comprising a first lens and a second lens, and scanners at the Fourier plane where the focal length of the first lens and the second lens meet. The platform may rotate around an axis aligned with a spatial light modulator. When the platform rotates, the scanners rotate, thereby de-rotating a SAW image. The second lens may be a spherical reflective surface for redirecting light from the spatial light modulator, having passed through the first lens and reflected off a mirror-scanner, toward a user's eyes. The user may be on a chair above the spatial light modulator, wherein the chair is configured to rotate with the spatial light modulator.

公开(公告)号：US10346568B2

公开(公告)日：2019-07-09

申请号：US13946888

申请日：2013-07-19

Applicant: Brigham Young University

Inventor： Walter Edward Red ,  Charles Gregory Jensen ,  Prasad Weerakoon ,  Jingsi (James) Wu ,  Karl Merkley ,  Jared Briggs

IPC: G06F17/50

Abstract: A method for collaborative finite analysis may include obtaining an electronic model of an engineering object, assigning users one or more geometries for pre-analysis editing to provide assigned geometries for each user, and enabling each user to conduct pre-analysis editing of their assigned geometries concurrent with other users. The method may also include conducting finite analysis on the assigned geometries of a first user concurrent with conducting finite analysis on the assigned geometries of a second user. Examples of pre-analysis editing include removing features that are secondary to analysis, applying a material definition to a geometry, pre-meshing a geometry, initiating automated meshing of a geometry, validating automated meshing of a geometry, editing a mesh for a geometry, manually meshing a geometry, defining one or more loads associated with a geometry, and defining one or more boundary conditions for a geometry. A corresponding system and apparatus are also disclosed herein.

公开(公告)号：US20180375490A1

公开(公告)日：2018-12-27

申请号：US16032951

申请日：2018-07-11

Applicant: Brigham Young University

Inventor： Daniel Smalley

IPC: H03H9/02 ,  G02B6/122 ,  H01S3/094 ,  G02B6/02

Abstract: A method and system for using laser-induced structures to direct light to exit the bottom of a leaky mode device, and further to divide leaky mode light into multiple orders, and to implement one or more pulsing/strobing patterns such that a field of view is increased for a viewer, or the view zone is increased for a viewer. A leaky mode device may comprise a substrate, a surface acoustic wave (“SAW”) transducer, a waveguide having a higher refractive index than the substrate, an input region for input light, and laser induced structures such as grating. The SAW transducer may be positioned on a top surface of the substrate, and may be configured to emit a SAW wave to propagate across the substrate. The waveguide may be positioned below the SAW. The input wave region may be configured to couple light onto the waveguide. When light is coupled onto the waveguide, the refractive index may change such that the light in the waveguide exits the waveguide as leaky mode light and interacts with the laser-induced grating, which is below the waveguide. The laser-induced grating is configured to divide the leaky mode light into multiple orders, each bent at a different angle.