Abstract:
The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition, the invention provides diagnostic kits for Mtb.
Abstract:
Methods for affecting body composition include the use of amylin or amylin agonist(s). Total body weight may be reduced, maintained or even increased; however, the body fat is reduced or body fat gain is prevented, while lean body mass is maintained or increased.
Abstract:
A variable cam timing system for an engine with at least one camshaft comprising: a housing, a rotor, and a controlled bypass. The housing has an outer circumference for accepting drive force and chambers. The rotor has a connection to a camshaft coaxially located within the housing. The housing and the rotor define at least one vane separating a chamber in the housing into advance and retard chambers. The vane is capable of rotation to shift the relative angular position of the housing and the rotor. The controlled bypass provides fluid communication between the chambers. When the valve is closed, the valve blocks passage between the chambers and when the valve is open fluid flows through the passage extending between the advance chamber to the retard chamber. A method for reducing the valve event is also disclosed.
Abstract:
HMGCo-A reductase inhibitor compounds useful as hypocholesterolemic and hypolipidemic compounds are provided. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.
Abstract:
The present invention relates to a piston adapted for reciprocal movement within the cylinders of an internal combustion engine. The piston includes a body having a crown formed at the uppermost margins of the body and a skirt, depending from the crown, adapted for relative sliding motion with respect to the cylinder. The piston further includes a coating bonded to the piston skirt so as to be juxtaposed between the skirt and the cylinder. The coating has a plurality of recesses formed thereon so as to define a predetermined pattern of recesses on the surface of the skirt that retains lubricant between the skirt and the cylinder wall. The coating may also direct lubricant along the outer circumference of the piston skirt during reciprocal movement of the piston within a cylinder. A method of applying the coating to the piston skirt is also disclosed.
Abstract:
Methods of rapidly generating and analyzing a plurality of polypeptides are disclosed. More specifically, libraries and arrays of polypeptides are assayed in order to determine their individual immunogenic effect. Based on the immunogenic effect of polypeptides, specific subunit vaccines can be developed.
Abstract:
A portable metal stud punching system has an alignment frame with an infeed alignment port in a first side and an outfeed alignment port in an opposite side. There is a punch and die positioned within the alignment frame. A length of metal stud is inserted through the infeed alignment port with one vertical side of the metal stud disposed between the punch and the die. A first hydraulic unit is attached to the punch and moves a first direction thereby inserting the punch into the die and punching a tab out of the vertical side of the metal stud. A second hydraulic unit moves the punch assembly in a direction perpendicular to the first direction of the first hydraulic unit. After the tab has been punched, the second hydraulic unit advances the metal stud by sliding the punch assembly a distance equal to the desired space between tabs. The punch is retracted by the first hydraulic unit and the punch assembly is returned to its original position by the second hydraulic unit.
Abstract:
Improved caching control for streaming media includes one or more cache control directives associated with streaming media content that can be used by a source of the streaming media content to identify how caching proxy servers are to handle the streaming media content. Upon receipt of the streaming media content, the caching proxy servers handle the content as indicated by the cache control directive(s).
Abstract:
The present invention provides compounds having the Formula I The present invention also provides pharmaceutical compositions comprising a compound of Formula I and methods of treatment of atherosclerosis, obesity, restenosis, coronary heart disease, hyperlipoproteinemia, hypercholesterolemia, and hypertriglyceridemia.