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公开(公告)号：US20230029805A1
公开(公告)日：2023-02-02
申请号：US17746798
申请日：2022-05-17
Applicant: Medlumics S.L.
Inventor： Juan SANCHO DURÁ , Sara MAS GÒMEZ , David GONZALEZ , Matthieu DUPERRON , Carlos SANZ MORENO , Jorge JIMENEZ , Alexandre ROMOSCANU
Abstract: Described herein are methods, devices, and support structures for assembling optical fibers in catheter tips and facilitating alignment and structural support. A method for assembling a plurality of optical fibers and lenses in a support structure for an ablation catheter includes providing a support structure with a proximal end, a body, and a distal end, the distal end including a plurality of alignment orifices or slits. A plurality of optical fibers are threaded through the alignment orifices or slits, such that each optical fiber is threaded through a corresponding alignment orifice or slit. An adhesive material is applied at each alignment orifice or slit to secure the optical fibers, and the plurality of optical fibers are then cleaved at the distal end to remove portions of the fibers extending out of the distal end. Finally, a lens is attached to each of the ends of the plurality of optical fibers.
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公开(公告)号：US11517199B2
公开(公告)日：2022-12-06
申请号：US16277863
申请日：2019-02-15
Applicant: Medlumics S.L.
Inventor： Eduardo Margallo Balbás , Alejandro Barriga Rivera , José Luis Rubio Guivernau , Santiago Jiménez Valero , Juan Lloret Soler
IPC: A61B5/00 , A61B17/00 , A61B5/02 , A61M25/09 , A61B1/00 , A61B1/07 , A61B18/18 , A61B17/22 , A61B18/00
Abstract: Embodiments for crossing an occlusion by controlling a guide with the aid of optical coherence tomography (OCT) data are described. Embodiments include transmitting one or more beams of radiation via one or more waveguides on a flexible substrate within a guide wire. One or more beams of scattered or reflected radiation may be received from a sample via one or more waveguides. Depth-resolved optical data of the sample may be generated based on the received beams of scattered or reflected radiation. The depth-resolved data may be used for determining at least one of a distance between the guide wire and a wall of the artery and a distance between the guide wire and an occlusion within the artery. A position of the guide wire within the artery may then be controlled based on the determined distance or distances.
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公开(公告)号：US20210212755A1
公开(公告)日：2021-07-15
申请号：US17148506
申请日：2021-01-13
Applicant: Medlumics S.L.
Inventor： Jorge JIMENEZ , David HERRANZ , James GREENE , Michael NAGY , Tyler PANIAN , Juan SANCHO , Matthieu DUPERRON
Abstract: Described herein is a system including a catheter, an optical circuit, a pulsed field ablation energy source, and a processing device. The catheter includes a proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. The optical circuit is configured to transport light at least partially from the proximal section to the distal section and back. The pulsed field ablation energy source is coupled to the catheter and configured to transmit pulsed electrical signals to a tissue sample. The processing device is configured to analyze one or more optical signals received from the optical circuit to determine changes in polarization or phase retardation of light reflected or scattered by the tissue sample, and determine changes in a birefringence of the tissue sample based on the changes in polarization or phase retardation.
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公开(公告)号：US20210077181A1
公开(公告)日：2021-03-18
申请号：US16950499
申请日：2020-11-17
Applicant: MEDLUMICS S.L.
Inventor： Eduardo Margallo Balbás , José Luis Rubio Guivernau , Santiago Jiménez Valero , Alejandro Barriga Rivera , Justo Contreras Bermejo , Juan Lloret Soler
Abstract: Systems and methods for performing RF ablation while monitoring the procedure using low coherence interferometry (LCI) data are described. A catheter includes a distal section, a proximal section, a multiplexer, and a sheath coupled between the distal section and the proximal section. The distal section includes one or more electrodes configured to apply RF energy to a portion of a sample in contact with the electrode. The distal section also includes a plurality of optical elements configured to transmit one or more beams of exposure radiation away from the distal section of the catheter. The proximal section includes an optical source configured to generate a source beam of radiation and a detector configured to generate depth-resolved optical data. The multiplexer is configured to generate the one or more beams of exposure radiation from the source beam of radiation.
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公开(公告)号：US10820806B2
公开(公告)日：2020-11-03
申请号：US16222284
申请日：2018-12-17
Applicant: Medlumics S.L.
Abstract: A medical instrument is described that includes an optical source, an optical fiber, and a waveguide patterned upon a substrate. The optical fiber receives radiation from the optical source and includes a first segment and a second segment. The second segment is rotated about an optical axis relative to the first segment. The waveguide receives radiation from the optical source and guides a beam of radiation. The waveguide includes a first waveguide segment designed to impart a first differential group delay on the beam of radiation and a second waveguide segment designed to impart a second differential group delay on the beam of radiation. A sum of the first differential group delay and the second differential group delay is substantially zero.
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Patent Agency Ranking
公开(公告)号：US20190192005A1
公开(公告)日：2019-06-27
申请号：US16222284
申请日：2018-12-17
Applicant: Medlumics S.L.
Abstract: A medical instrument is described that includes an optical source, an optical fiber, and a waveguide patterned upon a substrate. The optical fiber receives radiation from the optical source and includes a first segment and a second segment. The second segment is rotated about an optical axis relative to the first segment. The waveguide receives radiation from the optical source and guides a beam of radiation. The waveguide includes a first waveguide segment designed to impart a first differential group delay on the beam of radiation and a second waveguide segment designed to impart a second differential group delay on the beam of radiation. A sum of the first differential group delay and the second differential group delay is substantially zero.
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公开(公告)号：US10206584B2
公开(公告)日：2019-02-19
申请号：US14820255
申请日：2015-08-06
Applicant: Medlumics S.L.
Inventor： Eduardo Margallo Balbás , Alejandro Barriga Rivera , José Luis Rubio Guivernau , Santiago Jiménez Valero , Juan Lloret Soler
IPC: A61B5/00 , A61B5/02 , A61M25/09 , A61B1/00 , A61B1/07 , A61B18/18 , A61B17/00 , A61B17/22 , A61B18/00
Abstract: Systems and methods for controlling a guide with the aid of optical coherence tomography (OCT) data are described. A guide wire includes at least one optical fiber, a flexible substrate, and one or more optical elements. The at least one optical fiber transmits a source beam of radiation. The flexible substrate includes a plurality of waveguides. At least one of the plurality of waveguides transmits one or more beams of radiation away from the guide wire, and at least one of the plurality of waveguides receives one or more beams of scattered radiation that have been reflected or scattered from a sample. The multiplexer generates the one or more beams of exposure radiation from the source beam of radiation. The one or more optical elements at least one of focus and steer the one or more beams of radiation.
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公开(公告)号：US09829628B2
公开(公告)日：2017-11-28
申请号：US15448663
申请日：2017-03-03
Applicant: Medlumics S.L.
Inventor： Kirill Zinoviev , José Luis Rubio Guivernau
CPC classification number: G02B6/122 , G02B6/136 , G02B2006/12061 , G02B2006/12097 , G02B2006/12135 , G02B2006/12142 , G02F1/025
Abstract: A device and a method for manufacturing the device are presented. The device includes a ridge, a peninsula formation, and a conductive trace. The ridge is defined within a semiconducting material. The peninsula formation is also defined within the semiconducting material and is adjacent to the ridge such that a gap exists between an end face of the peninsula formation and a side wall of the ridge. The conductive trace bridges across the gap such that the conductive trace runs over a top surface of the peninsula and a top surface of the ridge.
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公开(公告)号：US09739940B2
公开(公告)日：2017-08-22
申请号：US15065126
申请日：2016-03-09
Applicant: Medlumics S.L.
Inventor： José Luis Rubio Guivernau , Juan Sancho Durá , Eduardo Margallo Balbás
CPC classification number: G02B6/122 , G02B6/12 , G02B6/12004 , G02B6/124 , G02B6/2861 , G02B6/29331 , G02B6/29332 , G02B6/29344 , G02B6/29352 , G02B2006/12104 , G02B2006/12142 , G02B2006/12147 , H01S5/1028
Abstract: A photonic integrated circuit is presented that includes a substrate, and a first and second waveguide patterned on the substrate. The first waveguide guides an input beam of radiation. The photonic integrated circuit also includes a coupling region, wherein the first and second waveguides each pass through the coupling region. One or more modulating elements are coupled to each of the first and second waveguides. The first waveguide and the second waveguide have a first facet and a second facet, respectively, and first and second reflections are generated at the first and second facets within the first and second waveguides, respectively. The one or more modulating elements coupled to each of the first and second waveguides are designed to adjust the phase of the first and second reflections before the first and second reflections pass through the coupling region.
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公开(公告)号：US09588291B2
公开(公告)日：2017-03-07
申请号：US14584592
申请日：2014-12-29
Applicant: Medlumics S.L.
Inventor： Kirill Zinoviev , José Luis Rubio Guivernau
CPC classification number: G02B6/122 , G02B6/136 , G02B2006/12061 , G02B2006/12097 , G02B2006/12135 , G02B2006/12142 , G02F1/025
Abstract: A device and a method for manufacturing the device are presented. The device includes a ridge, a peninsula formation, and a conductive trace. The ridge is defined within a semiconducting material. The peninsula formation is also defined within the semiconducting material and is adjacent to the ridge such that a gap exists between an end face of the peninsula formation and a side wall of the ridge. The conductive trace bridges across the gap such that the conductive trace runs over a top surface of the peninsula and a top surface of the ridge.
Abstract translation: 提出了一种用于制造该装置的装置和方法。 该装置包括脊，半岛形状和导电迹线。 脊部限定在半导体材料内。 半岛形成也限定在半导体材料内并且与脊相邻，使得在半岛形状的端面和脊的侧壁之间存在间隙。 导电迹线穿过间隙桥接，使得导电迹线在半岛的顶表面和脊的顶表面上延伸。
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