公开(公告)号：US20230320592A1

公开(公告)日：2023-10-12

申请号：US18079667

申请日：2022-12-12

Applicant: Medlumics S.L.

Inventor： Juan SANCHO DURÁ ,  Sara MAS GÓMEZ ,  David GONZALEZ ,  Matthieu DUPERRON ,  Carlos SANZ MORENO ,  Jorge JIMENEZ ,  Alexandre ROMOSCANU ,  David HERRANZ ARAGONCILLO

IPC: A61B5/00 ,  A61B18/02 ,  A61B18/14 ,  A61B18/20 ,  A61B18/24

CPC classification number: A61B5/0084 ,  A61B5/0066 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/20 ,  A61B18/24 ,  A61B2090/309

Abstract: Described herein are systems and methods for performing optical signal analysis and lesion predictions in ablations. A system includes a catheter coupled to a plurality of optical fibers via a connector that interfaces with a computing device. The computing device includes a memory and a processor configured to receive optical measurement data of a portion of tissue from the catheter. The processor identifies one or more optical properties of the portion of tissue by analyzing the optical measurement data and determines a time of denaturation of the portion of tissue based on the one or more optical properties. A model is created to represent a correlation between lesion depths and ablation times using the time of denaturation, the one or more optical properties, and the predetermined period of time. A predicted lesion depth for a predetermined ablation time is generated using the model.

公开(公告)号：US20210212569A1

公开(公告)日：2021-07-15

申请号：US17148480

申请日：2021-01-13

Applicant: Medlumics S.L.

Inventor： Juan SANCHO DURÁ ,  Sara MAS GÓMEZ ,  David GONZALEZ ,  Matthieu DUPERRON ,  Carlos SANZ MORENO ,  Jorge JIMENEZ ,  Alexandre ROMOSCANU

IPC: A61B5/00 ,  A61B18/14 ,  A61B18/24 ,  A61B18/02 ,  A61B18/20

Abstract: Described herein are systems and methods for performing optical signal analysis and lesion predictions in ablations. A system includes a catheter coupled to a plurality of optical fibers via a connector that interfaces with a computing device. The computing device includes a memory and a processor configured to receive optical measurement data of a portion of tissue from the catheter. The processor identifies one or more optical properties of the portion of tissue by analyzing the optical measurement data and determines a time of denaturation of the portion of tissue based on the one or more optical properties. A model is created to represent a correlation between lesion depths and ablation times using the time of denaturation, the one or more optical properties, and the predetermined period of time. A predicted lesion depth for a predetermined ablation time is generated using the model.

公开(公告)号：US20230029805A1

公开(公告)日：2023-02-02

申请号：US17746798

申请日：2022-05-17

Applicant: Medlumics S.L.

Inventor： Juan SANCHO DURÁ ,  Sara MAS GÒMEZ ,  David GONZALEZ ,  Matthieu DUPERRON ,  Carlos SANZ MORENO ,  Jorge JIMENEZ ,  Alexandre ROMOSCANU

IPC: A61B18/18 ,  G02B6/26 ,  A61M25/00

Abstract: Described herein are methods, devices, and support structures for assembling optical fibers in catheter tips and facilitating alignment and structural support. A method for assembling a plurality of optical fibers and lenses in a support structure for an ablation catheter includes providing a support structure with a proximal end, a body, and a distal end, the distal end including a plurality of alignment orifices or slits. A plurality of optical fibers are threaded through the alignment orifices or slits, such that each optical fiber is threaded through a corresponding alignment orifice or slit. An adhesive material is applied at each alignment orifice or slit to secure the optical fibers, and the plurality of optical fibers are then cleaved at the distal end to remove portions of the fibers extending out of the distal end. Finally, a lens is attached to each of the ends of the plurality of optical fibers.

公开(公告)号：US20210212755A1

公开(公告)日：2021-07-15

申请号：US17148506

申请日：2021-01-13

Applicant: Medlumics S.L.

Inventor： Jorge JIMENEZ ,  David HERRANZ ,  James GREENE ,  Michael NAGY ,  Tyler PANIAN ,  Juan SANCHO ,  Matthieu DUPERRON

IPC: A61B18/14 ,  A61B18/12

Abstract: Described herein is a system including a catheter, an optical circuit, a pulsed field ablation energy source, and a processing device. The catheter includes a proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. The optical circuit is configured to transport light at least partially from the proximal section to the distal section and back. The pulsed field ablation energy source is coupled to the catheter and configured to transmit pulsed electrical signals to a tissue sample. The processing device is configured to analyze one or more optical signals received from the optical circuit to determine changes in polarization or phase retardation of light reflected or scattered by the tissue sample, and determine changes in a birefringence of the tissue sample based on the changes in polarization or phase retardation.